Clinical trials: Type 2 Diabetes, completed
Gastroparesis, Diabetes Mellitus
Effects of Sitagliptin on Gastric Emptying, Glycaemia and Blood Pressure in Type 2 Diabetes
The purpose of this study is to evaluate the acute effects of sitagliptin on postprandial glycemia, incretin hormones and blood pressure, and the relationship to gastric emptying, after a mashed potato meal in patients with type…
- Trial name
- NCT02324010
- Testing
- Sitagliptin
- Where
- Australia
- Volunteers
- 14 people
- Sponsor
- Royal Adelaide Hospital
Type2 Diabetes Mellitus
IRAPe, Irisin and IL-34 in Patients With Type 2 Diabetes
Aim: This study aimed to evaluate the role of extracellular part of insulin regulated aminopeptidase (IRAPe), IL-34, Irisin, and Visfatin in the development of insulin resistance in patients with type 2 diabetes mellitus.
- Trial name
- NCT04107259
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour University
Diabetes Mellitus, Type 2
An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin
The main purpose of this study is to assess the effects of 4 weeks each of daily treatment with canagliflozin 300 milligram (mg) versus sitagliptin 100 mg as treatment adjuncts to metformin (at stable dosages) on intrapatient…
- Trial name
- COMETA (NCT03267576)
- Testing
- Canagliflozin 300 mg, Sitagliptin 100 mg, Metformin
- Where
- 5 sites in Mexico
- Volunteers
- 64 people
- Sponsor
- Janssen Research & Development, LLC
Diabetes Mellitus Type II
EPA Supplementation on Vascular Inflammation, and Gene Expression of PON2 in Patients With Type II Diabetes Mellitus
The aim of this study is to determining of the effects of Eicosapentaenoic acid (EPA) supplementation on serum activities of Paraoxonase-1 and Homocystein thiolactonase, and serum levels of some indicators of vascular…
- Trial name
- NCT03258840
- Testing
- EPA Supplement
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Tehran University of Medical Sciences
Diabetes Mellitus, Type II
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Type 2 Diabetes Mellitus (T2DM) is a disease that interferes with the body's proper production and use of insulin, a hormone needed to convert sugar into usable energy.
- Trial name
- T2DM (NCT00577590)
- Testing
- Metformin, Rosiglitazone, Lovaza
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes Mellitus, Telenursing
Telecoaching of People With Type 2 Diabetes in Primary Care
The objective of the study is to analyze the effectiveness and the cost-effectiveness of telecoching in improving glyceamic control and other modifiable risk factors in patients with type 2 diabetes compared to usual care only.
- Trial name
- NCT01612520
- Testing
- telecoaching
- Volunteers
- 574 people
- Sponsor
- KU Leuven
Impaired Glucose Tolerance
Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D)
Lipotoxicity-causing fatty acid overexposure and accretion in lean tissues leads to insulin resistance and impaired pancreatic β-cell function - the hallmarks of T2D - contributing to associated complications such as heart…
- Trial name
- AGL11 (NCT02808182)
- Testing
- Nicotinic acid, [7,7,8,8-2H]-palmitate, [U-13C]-palmitate
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pre-Existing Type 2 Diabetes Mellitus
Self-management and Quality of Life in Individuals With Type 2 Diabetes Mellitus
The study was conducted in order to study the effect of the training given according to social-cognitive learning theory (SCLT) upon diabetes self-management and quality of life among type 2 diabetes mellitus individuals.
- Trial name
- NCT05983120
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetes Mellitus, Type 2
Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 Diabetes
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending-doses of TAK-875 in subjects with type 2 diabetes mellitus.
- Trial name
- NCT00949091
- Testing
- TAK-875
- Volunteers
- 60 people
- Sponsor
- Takeda
Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2
A Study to Compare the Effect on Heart Rhythm of 3 Days of GSK189075, Placebo, or Moxifloxacin in Healthy Adults
This study assesses for change in heart rhythm of healthy volunteers taking GSK189075 for 3 days at a normal dose and a higher than normal dose compared to placebo or to a single dose of moxifloxacin.
- Trial name
- NCT00532610
- Testing
- GSK189075
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes
Safety and Efficacy of Dapagliflozin in Triple Therapy to Treat Subjects With Type 2 Diabetes
The purpose of this study is to learn if BMS-512148 (Dapagliflozin) as part of a triple combination therapy can improve (decrease) hemoglobin A1c in patients with type 2 diabetes after 24 weeks of treatment compared to a 2 drug…
- Trial name
- NCT01646320
- Testing
- Dapagliflozin, Saxagliptin, Metformin immediate release (IR)
- Where
- 66 sites in United States, Czechia and 6 more
- Volunteers
- 320 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2, Ischemic Heart Disease
Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor
Type 2 diabetes mellitus (type 2 DM) is an important disease with increasing prevalence worldwide. More than 60% of diabetes patients die of CVD.
- Trial name
- NCT03178591
- Testing
- vildagliptin, Dapagliflozin
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Chiang Mai University
Type 2 Diabetes
Mobile Phone Support for Adults and Support Persons to Live Well With Diabetes
This study evaluates a mobile phone-delivered intervention (FAMS 2.0; Family/friend Activation to Motivate Self-care) designed to help adults with type 2 diabetes set and achieve self-care goals and improve the quality of…
- Trial name
- FAMS 2 (NCT04347291)
- Testing
- FAMS 2.0, Print Materials
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- Vanderbilt University Medical Center
Overweight and Obesity, Aging
NR Supplementation and Exercise
The number of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is increasing rapidly worldwide, reaching pandemic proportions.
- Conditions
- Overweight and Obesity, Aging, Type 2 Diabetes
- Trial name
- NCT04907110
- Testing
- Niagen, Exercise
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Type 2
Morphological Pancreatic Features in Diabetes Mellitus Type 2
Hypothesis: Type 2 diabetes mellitus is associated with pancreatic fibrosis that can be evaluated by minimally invasive imaging techniques.
- Trial name
- PANDIAM (NCT05762653)
- Testing
- Endoscopic ultrasound
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Type 2 Diabetes
Exercise Intensity and Type 2 Diabetics
The purpose of this study is to determine if a single session of aerobic exercise effectively controls the blood pressure (BP) of individuals with type 2 diabetes mellitus (T2DM) over the 24h of post-exercise period, and the…
- Trial name
- EIT2D (NCT01356953)
- Testing
- Aerobic exercise
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Catholic University of Brasília
Type 2 Diabetes Mellitus
Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes
Short-term intensive insulin therapy(SIIT) is able to reverse β cell dysfunction and induce glycemic remission in patients with newly diagnosed type 2 diabetes.
- Trial name
- NCT03194945
- Testing
- CSII followed by Lina+MET, CSII followed by Lina, CSII followed by MET
- Where
- China
- Volunteers
- 412 people
- Sponsor
- Sun Yat-sen University
Type2 Diabetes, Diabetes Mellitus, Type 2
Effects of Basic Carbohydrate Counting Versus Standard Outpatient Nutritional Education in Type 2 Diabetes
The aim of the study is to examine the health benefits of adding a concept in basic carbohydrate counting (BCC) to the routine outpatient nutritional education for adult patients with type 2 diabetes.
- Conditions
- Type2 Diabetes, Diabetes Mellitus, Type 2, Glucose Metabolism Disorders
- Trial name
- NCT03623139
- Testing
- Standard nutritional education, Basic carbohydrate counting
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Mellitus, Type 2
The Fruit and Vegetable Prescription Program Study
The Fruit and Vegetable Prescription Program Study is a pilot randomized controlled trial of patients with type 2 diabetes participating in a fruit and vegetable prescription program from a Federally Qualified Health Center in…
- Trial name
- NCT04597957
- Testing
- Fresh Rx Intervention group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Henry Ford Health System
Diabetes Mellitus Type 2
Effect of Androgel on Type 2 Diabetic Males With Hypogonadism
This is to study the effect of replacing testosterone on different inflammatory cells in type 2 diabetics with low testosterone levels.
- Trial name
- NCT00350701
- Testing
- androgel, androgel 10g
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University at Buffalo
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