Clinical trials: Type 2 Diabetes, completed
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Diabetes Mellitus, Type 2
Effects of Nutritional Products on Blood Glucose in Subjects With Type 2 Diabetes
To evaluate average daily blood glucose in subjects with type 2 diabetes following a Meal Plan including Diabetes-Specific products compared to average daily blood glucose in subjects following their usual diet.
- Trial name
- NCT00753181
- Testing
- Nutritional Formula, Usual diet, Diabetes Meal Plan with experimental diabetes-specific nutritional shake, diabetes specific cereal, and diabetes specific snack bars.
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Abbott Nutrition
Diabetes Mellitus, Type 2
Effect of AC2993 Compared With Insulin Glargine in Patients With Type 2 Diabetes Also Using Combination Therapy With Sulfonylurea and Metformin
This is a multicenter, comparator-controlled, open-label, randomized, two-arm, parallel trial to compare the effect of exenatide twice daily and insulin glargine on glycemic control, as measured by hemoglobin A1c (HbA1c).
- Trial name
- NCT00082381
- Testing
- Exenatide (AC2993), Insulin glargine
- Where
- 91 sites in United States, Australia and 11 more
- Volunteers
- 551 people
- Sponsor
- AstraZeneca
Type 2 Diabetes
Characteristics of Empagliflozin Initiators
Empagliflozin, a sodium glucose cotransporter 2 (SGLT-2) inhibitor, was launched in the United Kingdom (UK) in August 2014. It can be expected that patients initiating empagliflozin may differ in their characteristics from…
- Trial name
- NCT03050619
- Testing
- Empagliflozin, Other SGLT2 inhibitors, Other non-insulin GLDs
- Where
- Germany
- Volunteers
- 31,908 people
- Sponsor
- Boehringer Ingelheim
PreDiabetes, Overweight and Obesity
Family Diabetes Prevention Program Pilot Study
This study will examine the feasibility and acceptability of a family-oriented augmentation of the Diabetes Prevention Program lifestyle intervention (DPP), called the Family DPP.
- Conditions
- PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood
- Trial name
- NCT05358444
- Testing
- National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Breast Cancer, PreDiabetes
Diabetes Care for Breast Cancer Patients
The goal of this study is to find a new way to make diabetes care better for patients with breast cancer and diabetes who are currently receiving cancer treatment.
- Conditions
- Breast Cancer, PreDiabetes, Type 2 Diabetes
- Trial name
- NCT05565534
- Testing
- Nurse-practitioner led intervention
- Where
- 3 sites in United States
- Volunteers
- 74 people
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes Mellitus
A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the safety and potential effectiveness of CCX140-B in subjects with Type 2 diabetes mellitus.
- Trial name
- NCT01028963
- Testing
- pioglitazone, CCX140-B
- Where
- 28 sites in Australia, Czechia and 3 more
- Volunteers
- 159 people
- Sponsor
- Amgen
Chronic Periodontitis, Diabetes Mellitus
Low-level Laser Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
The aim of this study was to investigate the local effect of adjunct low-level laser therapy (LLLT) for the treatment of moderate to severe chronic periodontitis in type 2 diabetic patients.
- Trial name
- NCT02817152
- Testing
- Periodontal ultrasonic debridement, Debridement plus low-level laser therapy
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Diabetes Mellitus Type 2, Hypercholesterolemia
Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes
It is of interest how ezetimibe alone or in combination with statin may influence atherogenic dense Low Density Lipoprotein (dLDL) in patients with type 2 diabetes mellitus.
- Trial name
- EZE (NCT01384058)
- Testing
- ezetimibe, simvastatin, Ezetimibe 10/Simvastatin 20
- Where
- 2 sites in Germany
- Volunteers
- 41 people
- Sponsor
- University Hospital Freiburg
Type 2 Diabetes Mellitus
Sitagliptin Added-on to Insulin Study (0431-051)
A clinical study to determine the safety and efficacy of sitagliptin in patients with Type 2 Diabetes Mellitus who have inadequate glycemic control on insulin or insulin/metformin combination therapy.
- Trial name
- NCT00395343
- Testing
- sitagliptin phosphate
- Volunteers
- 641 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2, Insulin Resistance
Carnitine and Liver Mitochondria Fatty Acid Processing
This double-blind, placebo-controlled randomized trial will assess whether 14 days of oral carnitine supplementation modifies mitochondrial fatty acid processing in healthy young adults.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Obesity
- Trial name
- NCT03193125
- Testing
- L-Carnitine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sexual Dysfunction, Sexual Abstinence
Using of Testes' Shocker in Improving Sexual Activity
Using of testes' shocker in treating the sexual dysfunction.
- Conditions
- Sexual Dysfunction, Sexual Abstinence, Sexual Desire Disorder, Erectile Dysfunction
- Trial name
- NCT04662398
- Testing
- JT Device
- Where
- Iraq
- Volunteers
- 77 people
- Sponsor
- University of Baghdad
Diabetes Mellitus, Type 2
Study of Insulin Lispro in Participants With Inadequately Controlled Type 2 Diabetes
Evidence regarding optimal methods of insulin dose adjustment is lacking in the literature. The purpose of this study is to evaluate the efficacy and safety of two approaches to escalate prandial insulin therapy in participants…
- Trial name
- AUTONOMY (NCT01215955)
- Testing
- Insulin lispro, Glargine
- Where
- 76 sites in United States, Argentina and 13 more
- Volunteers
- 1,117 people
- Sponsor
- Eli Lilly and Company
Diabetes, Diabetes Mellitus, Type 2
Observational Study of Safety and Efficacy of Levemir® in Type 2 Diabetes
The study is conducted in Asia. The aim of this observational study is to evaluate the weight change from baseline while using Levemir® in subjects with type 2 diabetes mellitus under normal clinical practice conditions in India.
- Trial name
- DIABESITY (NCT00687063)
- Testing
- insulin detemir
- Where
- India
- Volunteers
- 10,008 people
- Sponsor
- Novo Nordisk A/S
Hypogonadism, Male, Diabetes Mellitus, Type 2
Study on Effects of Testosterone Replacement Therapy in Hypogonadal Type 2 Diabetic Patients" (SETH2)
Aim of the study was to investigate the effects of testosterone replacement therapy on components of metabolic syndrome, vascular function and morphology, grade of non-alcoholic fatty liver disease (NAFLD), bone mineral density…
- Conditions
- Hypogonadism, Male, Diabetes Mellitus, Type 2, Obesity
- Trial name
- SETH2 (NCT03792321)
- Testing
- Testosterone Undecanoate
- Volunteers
- 55 people
- Sponsor
- University Medical Centre Ljubljana
Diabetes Mellitus, Type 2
12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients
The objective is to investigate the efficacy, safety and pharmacokinetics of three different doses of BI 10773 compared to placebo given for 12 weeks in patients with type 2 diabetes mellitus with insufficient glycemic control.
- Trial name
- NCT00789035
- Testing
- BI 10773, metformin
- Where
- 74 sites in Argentina, Croatia and 11 more
- Volunteers
- 408 people
- Sponsor
- Boehringer Ingelheim
Macroalbuminuric Diabetic Nephropathy
Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus
Chronic kidney disease (CKD)has become a significant health problem worldwide. Strategies to decrease the rate of progression of this disease and reduce the number of patients needing dialysis or renal transplantation are…
- Trial name
- NCT00419835
- Testing
- enalapril, losartan
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo
Type 2 Diabetes Mellitus
The Practical Evidence of Antidiabetic Combination Therapy in Korea
This study evaluate the efficacy and safety of alogliptin and pioglitazone combination therapy in comparison with either alogliptin or pioglitazone on glucose control in the metformin-treated type 2 diabetic patients in Korea.
- Trial name
- PEAK (NCT02231021)
- Testing
- alogliptin, Pioglitazone, alogliptin + pioglitazone
- Where
- South Korea
- Volunteers
- 216 people
- Sponsor
- Kun-Ho Yoon
Diabetes Mellitus, Type 2
Exploratory Study to Access the Metabolic Effects of Ranolazine in Subjects With Type 2 Diabetes Mellitus When Added to Ongoing Non-insulin Antidiabetic Therapy
This study enrolled participants with inadequately controlled type 2 diabetes mellitus (T2DM) despite non-insulin antidiabetic therapy in addition to diet and exercise, and would have benefited from additional control of blood…
- Trial name
- NCT01163721
- Testing
- Ranolazine
- Where
- 9 sites in United States
- Volunteers
- 80 people
- Sponsor
- Gilead Sciences
Diabetic Neuropathies
Role of Synchronized Lifestyle Modification Program in Insulin Dependent Diabetic Peripheral Neuropathy Patients
This study aims to determine the role of Synchronized Lifestyle modification program along with Physiotherapy on the symptoms of DPN in patients on insulin therapy.
- Trial name
- NCT04813133
- Testing
- Synchronized Lifestyle Modification Program, Synchronized Lifestyle Modification Program and Physiotherapy, Physiotherapy
- Where
- Pakistan
- Volunteers
- 216 people
- Sponsor
- Riphah International University
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