Clinical trials: Type 2 Diabetes Mellitus
Periodontitis, Diabetes
Effect of Non Surgical Treatment of Periodontitis on Diabetes Control
The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients.
- Trial name
- PARODIA1 (NCT02745015)
- Testing
- non-surgical periodontal treatment
- Where
- Cameroon
- Volunteers
- 45 people
- Sponsor
- Yaounde Central Hospital
Insulin-requiring Type 2 Diabetes Mellitus
Establishing Cardiovascular Biomarkers to Define Preferred Lantus® Use
The aim of this study is to observe changes in cardiovascular biomarkers during treatment with Lantus in patients with Type 2 Diabetes mellitus.
- Trial name
- NCT01500850
- Testing
- nph insulin, human insulin, Insulin Glargine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- ikfe-CRO GmbH
Diabetes Mellitus, Type 2, Ischemic Heart Disease
Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor
Type 2 diabetes mellitus (type 2 DM) is an important disease with increasing prevalence worldwide. More than 60% of diabetes patients die of CVD.
- Trial name
- NCT03178591
- Testing
- vildagliptin, Dapagliflozin
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Chiang Mai University
T2DM (Type 2 Diabetes Mellitus)
A Study of RAY1225 in Participants With Type 2 Diabetes
The main purpose of this study is to learn more about the Tolerability of RAY1225 in participants with type 2 diabetes mellitus. The study will also explore the efficacy of RAY1225.
- Trial name
- NCT06254274
- Testing
- RAY1225
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Diabetic Nephropathies, Diabetes Mellitus, Type II
Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy
Background The relationship between long-term heavy lead exposure and chronic interstitial nephropathy is well recognized in the previous literatures.
- Trial name
- NCT00237952
- Testing
- EDTA chelating agents
- Where
- 2 sites in China
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes, Heart Disease
The Effect of Alcohol on ABCA1 Expression and Lipid Metabolism
The purpose of this study is to investigate the effects of red wine on ABCA1 levels
- Trial name
- NCT00558935
- Testing
- Red Wine
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Diabetes Mellitus, Type II
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Type 2 Diabetes Mellitus (T2DM) is a disease that interferes with the body's proper production and use of insulin, a hormone needed to convert sugar into usable energy.
- Trial name
- T2DM (NCT00577590)
- Testing
- Metformin, Rosiglitazone, Lovaza
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes, Nephropathy
A Research Study to Evaluate the Renal (Kidney) Protective Effects of Losartan in Patients With Non-insulin Dependent Diabetes (0954-147)(COMPLETED)
Evaluate the effect of Losartan in reducing kidney disease in patients with Non-insulin Dependent Diabetes and Nephropathy (kidney damage that usually accompanies late stage Diabetes Mellitus).
- Trial name
- NCT00308347
- Testing
- MK0954, losartan / Duration of Treatment: mean 3.4 years
- Volunteers
- 1,513 people
- Sponsor
- Organon and Co
Gait, Unsteady, Aerobic Exercise
Neuromuscular Adaptations to Exercise In Patients With Type 2 Diabetes Mellitus
The aim of this study is to compare the effects of high intensity interval exercise and moderate intensity continuous exercise on basic gait parameters in patients with type 2 diabetes mellitus.
- Trial name
- NCT04068285
- Testing
- Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Pamukkale University
Diabetes Mellitis Type 2
A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects
This is a dose block-randomized, double-blind, placebo-controlled, single/multiple dosing, dose-escalation study. The study is designed to describe the relationship between multiple doses and pharmacokinetic/pharmacodynamic…
- Trial name
- NCT00961025
- Testing
- DA-1229
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Dilated Cardiomyopathy, Type 2 Diabetes
Myocardial Metabolism in Patients With Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is characterized by a metabolic shift from fat to carbohydrates and failure to increase myocardial glucose uptake in response to workload increments.
- Trial name
- NCT02440217
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Type 2 Diabetes Mellitus (T2DM), Psychological Distress
Effectiveness of a Diabetes Self-Management Program Among Ethnic Minority Elderly in Rural Thailand
Type 2 diabetes is a serious health condition that affects many older adults from ethnic minority communities in Northern Thailand.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Psychological Distress, Hyperglycemia
- Trial name
- DSM-EME (NCT07669389)
- Testing
- Diabetes Self-Management Education (DSME) Program, Usual Care
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Taipei Medical University
Insulin Resistance, Chronic Heart Failure
Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
The aim of the study is to evaluate the effect of metformin on myocardial function, insulin resistance and selected metabolic markers in patients with type 2 diabetes and heart failure (HF+DM+) in a cross-over, randomized…
- Trial name
- CARMET (NCT01690091)
- Testing
- Metformini hydrochloridum (Siofor 1000 tbl, Berlin)
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Diabetes
A Feasibility Study to Assess Critical Aspects of Fluorescence Affinity Sensor (FAS) Performance and Safety Over Several Hours
The goal of this clinical research study is to learn about a new minimally invasive glucose monitoring device called Fluorescence Affinity Sensor (FAS).
- Trial name
- FAS (NCT01065948)
- Testing
- Subcutaneous glucose monitoring device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- BioTex, Inc.
Obesity, Diabetes Mellitus, Non-Insulin-Dependent
Obese Patients With Type 2 Diabetes
To assess the effect on weight loss and weight maintenance over a period of one year when prescribed with a hypocaloric diet in obese patients with Type 2 Diabetes
- Conditions
- Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Obesity in Diabetes
- Trial name
- RIO-Diabetes (NCT00029848)
- Testing
- Rimonabant (SR141716)
- Where
- 55 sites in United States, Argentina and 9 more
- Volunteers
- 1,045 people
- Sponsor
- Sanofi
Type 2 Diabetes
Clinical Outcomes of Exenatide Versus Basal Insulin
This is a retrospective cohort study based on Clinical Practice Research Datalink (CPRD) database analysis to compare therapy effectiveness, and cost between exenatide and basal insulin in patients with type 2 diabetes.
- Trial name
- NCT02987348
- Testing
- exenatide once weekly, exenatide twice daily, basal insulin
- Where
- United Kingdom
- Volunteers
- 18,000 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Impact of Telehealth Education in Diabetes Patients
The goal of this clinical trial is to to evaluate the effectiveness of continuity of in-hospital care with the application of a structured telemonitoring protocol in self-care activities in patients with type 1 or type 2 Diabetes…
- Trial name
- NCT05696015
- Testing
- Standard education, Ampiled Education
- Volunteers
- 200 people
- Sponsor
- Hospital Israelita Albert Einstein
Hypertension, Type 2 Diabetes Mellitus (T2DM)
Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal
The goal of this clinical trial is to evaluate whether a multifaceted community-based intervention, comprising 1) screening and lifestyle counseling by female community health volunteers (FCHVs); community health workers in…
- Conditions
- Hypertension, Type 2 Diabetes Mellitus (T2DM), Tobacco Smoking
- Trial name
- SCALE NCD (NCT06740708)
- Testing
- SCALE-NCD
- Where
- Nepal
- Volunteers
- 2,100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetes Mellitus, Type 1
Evaluation of the Safety Use of the InsuPatch Device in Daily Life Conditions
The study is an open-label, randomized, two-period crossover study. Up to one hundred and twenty (120) subjects with type 1 diabetes mellitus (T1DM) who use the MiniMed paradigm insulin pump, who meet the inclusion/exclusion…
- Trial name
- Daily Life (NCT01283425)
- Testing
- InsuPatch
- Where
- 8 sites in United States, Israel
- Volunteers
- 147 people
- Sponsor
- Insuline Medical Ltd.
Type 2 Diabetes
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
The purpose of this study is to try and achieve similar glycemic control in general non-Intensive Care Unit (non-ICU) patients with Type 2 Diabetes with exenatide alone or in combination with basal insulin as compared to…
- Trial name
- NCT02455076
- Testing
- Exenatide, Glargine, Rapid-acting insulin analogs
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University