Clinical trials: Type 2 Diabetes Mellitus 1
Weight Loss
Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)
This study is one of two planned Phase 3 studies to support the weight management indication for VK2735 Oral in obese (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27kg/m2) adults with at least one weight-related comorbidity without type…
- Trial name
- NCT07868835
- Testing
- VK2735
- Volunteers
- 560 people
- Sponsor
- Viking Therapeutics, Inc.
Diabetes Mellitus, Type 2, Obesity
Epigenetics of Muscle Insulin Resistance
The investigators are trying to understand the role of DNA (deoxyribonucleic acid) methylation in insulin resistance in skeletal muscle and blood tissues.
- Trial name
- NCT03259984
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Type 2 Diabetes Mellitus
Efficacy and Safety of Twice-Daily Insulin Lispro Low Mixture Compared to a Once-Daily Long Acting Insulin Comparator in Patients Who Have Been Using One or More Oral Antihyperglycemic Agents Without Insulin
The purposes of this study are to determine: 1. If patients taking insulin lispro LM with metformin will have better overall control of their blood sugar than patients taking a long acting insulin comparator with metformin. 2.
- Trial name
- NCT00036504
- Testing
- Insulin Lispro low mixture
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
Feasibility of Non-invasive Glucose Monitoring by Using Photothermal Deflectometry
This study aims to evaluate the feasibility of non-invasive glucose monitoring by using photothermal deflectometry in the interstitial fluid of the skin on the wrist of subjects with diabetes mellitus type 1 and 2.
- Conditions
- Diabetes Mellitus Type 2, Diabetes Mellitus Type 1, Healthy
- Trial name
- NCT06088615
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Diamontech AG
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
A diagnosis of gestational diabetes mellitus (GDM)has significant implications for the future health of the mother. GDM is often the culmination of years of unrecognized and unmodified diabetes risk factors that lead to overt and…
- Conditions
- Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT01234649
- Testing
- Metformin XR plus liraglutide
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Woman's
Diabetes Mellitis Type 2
A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects
This is a dose block-randomized, double-blind, placebo-controlled, single/multiple dosing, dose-escalation study. The study is designed to describe the relationship between multiple doses and pharmacokinetic/pharmacodynamic…
- Trial name
- NCT00961025
- Testing
- DA-1229
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Diabetes Mellitus, Type 1, Type 2
Omnipod® SmartAdjust 2.0 System Compared to the Omnipod® 5 System in Individuals With Type 1 or Type 2 Diabetes
The goal of this multi-center, randomized, cross-over study is to evaluate the safety and effectiveness of the Omnipod 5 SmartAdjust 2.0 System in individuals with type 1 or type 2 diabetes.
- Trial name
- STRIVE (NCT06865989)
- Testing
- Omnipod 5 SmartAdjust 2.0 System, Omnipod 5 System
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Insulet Corporation
Type 1 or 2 Diabetes
Therapeutic Education of the Patients Diabetics Imprisoned at the Paris Jail
A lot of data show that therapeutic education is beneficial for diabetic patients. In the French jails, there are very few programs of therapeutic education while this population is usually precarious with no access at care…
- Trial name
- EPRIDIA (NCT02159417)
- Testing
- Therapeutic Education
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus, T1D
Simultaneous Measurement and Responsive Treatment - Part 2
This research study is testing an investigational dual-port insulin patch pump that integrates a continuous glucose monitor (CGM) in adults with type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus, T1D, Type 1 Diabetes, T1DM
- Trial name
- SMART02 (NCT07655076)
- Testing
- DPP System (Insulin Pump and Continuous Glucose Monitoring Platform)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- ClinSurge Research
Type 1 Diabetes, Organ Transplantation
Islet Cell Transplantation in Patients With Type I Diabetes With Previous Kidney Transplantation
This single center phase 2 clinical trial, is designed for confirming the efficacy and safety of sequential islet allotransplantation with steroid free immunosuppression in patients with previous kidney transplantation.
- Conditions
- Type 1 Diabetes, Organ Transplantation, Immunosuppression
- Trial name
- NCT01123187
- Testing
- islet transplantation
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Lille
Diabetes
Feasibility Study of a Novel Subcutaneous Continuous Glucose Monitoring System in Diabetics
Mono-centre, open label (unblinded). 8 patients + 2 potential replacements. Duration up to 9 weeks: up to 6 weeks screening (42 days), 2 weeks of treatment (14 days, depending on sensor functionality) and 1 week of follow up (7…
- Trial name
- FiberSense (NCT06867965)
- Testing
- BellySense
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- EyeSense GmbH
Type 1 Diabetes Mellitus
Pharmacodynamics, Pharmacokinetics, and Safety of ASP1941 in Patients With Type 1 Diabetes Mellitus
The objective of this study is to assess pharmacodynamics, pharmacokinetics, and safety of ASP1941 in patients with type 1 diabetes mellitus when administered once daily (q.d.) for 2 weeks.
- Trial name
- NCT02529449
- Testing
- ASP1941
- Where
- 11 sites in Japan
- Volunteers
- 43 people
- Sponsor
- Astellas Pharma Inc
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Comparison of Three Lancing Devices Regarding Capillary Blood Volume and Lancing Pain Intensity.
A randomized single-blind study with the use of three lancing devices equipped with personal lancets. Every device will be studied for three lancet sizes: 28G, 30G, and 33G with the minimum and maximum puncture depth setting.
- Trial name
- NCT03479619
- Testing
- Lancing device A, Lancing device B, Lancing device C
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- HTL-Strefa S.A.
Type 2 Diabetes
Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion
The present study is a phase I, single-centre, double-blind, randomized, cross-over (3 treatments, 3 treatment periods and 6 sequences), stratified (background medication: metformin vs.
- Trial name
- NCT02749032
- Testing
- Mixed meal test, Vildagliptin, Sitagliptin
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Michael A. Nauck
Type 1 Diabetes, Type 2 Diabetes
User Evaluation of the MiniMed 620G and 640G Insulin Pumps
This six center international study will include two United Kingdom National Health Service centers, two centers in Melbourne, Australia and one center each in Denmark and Spain.
- Trial name
- NCT01726621
- Testing
- Medtronic MiniMed 620G or 640G Insulin Pump
- Where
- 6 sites in Australia, Denmark and 2 more
- Volunteers
- 55 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Evaluation of the GlucoTrack, Non-Invasive Glucose Monitoring Device
The purpose of this study is to demonstrate the performance of the GlucoTrack device (non invasive device) in measuring blood glucose levels
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Gestational Diabetes
- Trial name
- NCT00433758
- Testing
- GlucoTrack
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Integrity Applications Ltd.
Diabetes Mellitus, Type 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes
The primary objective of the current study was to investigate the safety and tolerability of BI 1356 BS following administration of multiple rising oral doses of 1 mg, 2.5 mg, 5 mg, and 10 mg over 12 days in male patients with…
- Trial name
- NCT02183350
- Testing
- BI 1356 BS - single rising dose
- Volunteers
- 47 people
- Sponsor
- Boehringer Ingelheim
Obesity, Morbid, Diabetes Mellitus, Type 2
Impact of an Increased Restrictive Factor of One Anastomosis Gastric Bypass on Metabolic Outcomes Type 2 Diabetes.
The purpose of the study is to evaluate the effect of an increased restrictive factor of one gastric anastomosis (OAGB) using a "FundoRing" fundoplication on metabolic outcomes in type 2 diabetes mellitus.
- Trial name
- NCT06176443
- Testing
- One anastomosis gastric bypass with combined fundoplication, One anastomosis gastric bypass without combined fundoplication
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Diabetes Mellitus, Type 2
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)
This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to semaglutide taken once a week in people with type 2 diabetes.
- Trial name
- COMBINE 2 (NCT05259033)
- Testing
- IcoSema, Semaglutide 1 mg
- Where
- 193 sites in United States, Brazil and 13 more
- Volunteers
- 683 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Early Detection of Type 1 Diabetes
T1D is an autoimmune disease characterized by the presence of autoantibodies usually assayed separately on venous blood. The use of a combined test on capillary blood using a blotting paper would facilitate the immunological…
- Trial name
- PREDIDIA (NCT06984185)
- Testing
- combined assay on capillary blotting paper
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Hospices Civils de Lyon
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.