Clinical trials: Type 2 Diabetes Mellitus Remission
Type2 Diabetes
Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy
To evaluate the long-term remission rate of short-term intensive insulin (STII) therapy in newly diagnosed type 2 diabetes outpatients and investigate the predictors contributing to the remission rate.
- Trial name
- NCT03030300
- Testing
- Novolin 30R;Pioglitazone;Metformin
- Where
- 3 sites in China
- Volunteers
- 170 people
- Sponsor
- Qianfoshan Hospital
Type 2 Diabetes
REMIssion of Type 2 Diabetes Between Intermittently Scanned Continuous Glucose Monitoring and Capillary Blood Glucose Monitoring When Added to Low-calorie Meal Replacement and Diabetes Self-management Education
The goal of the study is to evaluate the effectiveness of intermittently scanned continuous glucose monitoring compared to capillary blood glucose monitoring among people with type 2 diabetes initiating low calorie meal…
- Trial name
- REMIT2D isCGM (NCT07157384)
- Testing
- Low calorie meal replacement plan, Diabetes self management education, Intermittently scanned continuous glucose monitoring
- Where
- 6 sites in Canada
- Volunteers
- 176 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Type 2 Diabetes Mellitus
Remission Through Early Monitored Insulin Therapy - Duration Month
REMIT-DM is a feasibility pilot study where participants will be recruited soon after their diagnosis of type 2 diabetes to be placed immediately on insulin therapy for maximum of four weeks with titrations of insulin guided by…
- Trial name
- REMIT-DM (NCT03670641)
- Testing
- Glargine, Lispro, Dexcom G6
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sandra Sobel
Type 2 Diabetes
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Type 2 diabetes mellitus is a chronic metabolic disorder characterized by progressive deterioration in the function of the pancreatic beta-cells, which are the cells that produce and secrete insulin (the hormone primarily…
- Trial name
- NCT01755468
- Testing
- Intermittent insulin therapy, Continuous metformin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Mount Sinai Hospital, Canada
Type 2 Diabetes, Obesity
Diabetes Data-Assisted Remission Trial (DDART)
The study team will study the efficacy of a high intensity medical weight loss intervention paired with a digital platform to create weight loss and induce remission of type 2 diabetes mellitus (T2DM) compared to a diabetes…
- Trial name
- NCT04663061
- Testing
- Medical weight loss, Diabetes education, Continuous glucose monitoring
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Type 2, Bariatric Surgery
Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial
In this study, the effects of SG with DJB and SG alone for the treatment of type 2 diabetes mellitus (T2DM) will be compared in patients other than the two groups at both extremes who are expected to show excellent effects of…
- Conditions
- Diabetes Mellitus, Type 2, Bariatric Surgery, Surgical Procedures, Operative, Asians
- Trial name
- NCT05211375
- Testing
- Duodenojejunal bypass, Sleeve gastrectomy
- Where
- South Korea
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
PreDiabetes, Prediabetic State
Henagliflozin's Impact on Prediabetes Remission
This clinical trial evaluates the effectiveness of Henagliflozin combined with lifestyle interventions for managing patients with prediabetes.
- Conditions
- PreDiabetes, Prediabetic State, Type 2 Diabetes, Glucose Metabolism Disorders
- Trial name
- NCT06448130
- Testing
- Henagliflozin 5mg, Henagliflozin 10mg
- Where
- 50 sites in China
- Volunteers
- 984 people
- Sponsor
- Shandong Provincial Hospital
Diabetes Mellitus, Type 2, Obesity
Who Will Benefit From Bariatric Surgery for Diabetes?
A study investigating the influence of fat distribution, genetic susceptibility markers for type 2 diabetes (T2DM) and fat distribution, epigenetic and transcriptomic changes and gut hormone responses to a mixed meal on diabetes…
- Trial name
- NCT03842475
- Testing
- Roux-en-Y gastric bypass (RYGB)
- Where
- United Kingdom
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Type 2 Diabetes
Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy
Whether GLP-1 receptor agonists sequential therapy in newly diagnosed type 2 diabetic patients can further improve glycemic control, diabetes remission rate and β-cell function after the short-term insulin intensive therapy.
- Trial name
- T2DMRS (NCT02129985)
- Testing
- Exenatide, Metformin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- xiaolong zhao
Type 2 Diabetes (T2DM)
Remission Evaluation of Metabolic Interventions in Type 2 Diabetes in Primary Care (REMIT-Prime)
The Remission Evaluation of Metabolic Interventions in Type 2 diabetes (REMIT) program incorporates a non-surgical-remission-inducing therapeutic approach, pairing health coaching with physician-led pharmacotherapy.
- Trial name
- REMIT-Prime (NCT07665567)
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McMaster University
Diabetes Mellitus, Type 2
Effect of Short-Term Intensive Insulin Sequential Exenatide Therapy in Newly Diagnosed Type 2 Diabetic Patients
The randomized, controlled trial is to investigate and evaluate the effects of short-term continuous subcutaneous insulin infusion (CSII) sequential exenatide therapy on β-cell function, long-term glycemic control and glycemic…
- Trial name
- NCT01776788
- Testing
- insulin lispro injection, exenatide injection, insulin lispro injection
- Where
- China
- Volunteers
- 156 people
- Sponsor
- The First Affiliated Hospital of Xiamen University