Clinical trials: Type 2 Diabetes Prevention
Diabetes Mellitus Type 2
(Cost-)Effectiveness of SLIMMER Diabetes Prevention Intervention
The overall aim of the project is to evaluate the (cost-)effectiveness of the SLIMMER diabetes prevention intervention in Dutch primary health care.
- Trial name
- SLIMMER (NCT02094911)
- Testing
- Combined lifestyle intervention, Usual care group
- Where
- Netherlands
- Volunteers
- 316 people
- Sponsor
- Wageningen University
Type 2 Diabetes
Qingdao Diabetes Prevention Project
Qingdao Diabetes Prevention Project aims to translate the trial experience to communities with specific objectives to: raise the public awareness of diabetes and diabetes risk factors promote healthy lifestyle of the entire…
- Trial name
- QDDPP (NCT01053195)
- Testing
- Lifestyle counseling
- Where
- China
- Volunteers
- 276,793 people
- Sponsor
- University of Helsinki
Pre-diabetes, Obesity
Effect of Diet and Physical Activity on Incidence of Type 2 Diabetes
Type-2 diabetes is one of the fastest growing chronic diseases worldwide. This trend is mainly driven by a global increase in the prevalence of obesity.
- Trial name
- PREVIEW (NCT01777893)
- Testing
- High protein/ high intensity physical activity (HP-HI), High protein / moderate intensity physical activity (HP-MI), Moderate protein/ high intensity physical activity (MP-HI)
- Where
- 9 sites in Australia, Bulgaria and 6 more
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Anne Birgitte Raben
Type 2 Diabetes Mellitus
Diabetes Prevention and Control in the Workplace: A Pilot Study
This worksite program for Onondaga County employees is a pilot research study aimed at decreasing the risk of developing diabetes (or improving metabolic control for adults with diabetes).
- Trial name
- NCT00739336
- Testing
- Diabetes Prevention and Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Prediabetes / Type 2 Diabetes
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
The study team will invite participants with prediabetes or mild diabetes (HbA1c 5.7-7.0) to join a 5-year research study that will define subphenotypes of type 2 diabetes based on underlying physiology (eg insulin resistance…
- Trial name
- NCT06682351
- Testing
- Metformin, GLP-1A, MED
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus, Nutritional and Metabolic Diseases
Nutritional Prevention of Diabetes Mellitus Type 2
This study investigates the influence of red meat and fibers on glucose metabolism and body fat composition in subjects at increased risk for type 2 diabetes.
- Conditions
- Type 2 Diabetes Mellitus, Nutritional and Metabolic Diseases, Liver Fat, Insulin Sensitivity
- Trial name
- NUPREDM (NCT03231839)
- Testing
- Caloric restriction, no red meat, Increased fiber intake
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- University Hospital Tuebingen
Type 2 Diabetes Mellitus
Evaluation of the Educational Program of Diabetes Mellitus: Focus on Empowerment
With health education, patients will have knowledge of the disease and may modify their attitudes to diabetes. Have a different behavior, will perform self-management of their health.
- Trial name
- NCT02132338
- Testing
- The Education Health Program
- Where
- Brazil
- Volunteers
- 191 people
- Sponsor
- Federal University of Minas Gerais
Diabetes Mellitus, Type 2, Metabolic Syndrome
A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians
The goal of the proposed research is to identify effective patient-centered strategies to prevent diabetes in high-risk populations in real world settings.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT02266576
- Testing
- Standard DPP, Enhanced DPP
- Where
- 2 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetes
Computer Based Intervention for Type 2 Diabetes in Youth
Interactive multimedia programs have been demonstrated to produce substantial change in children's dietary behaviors. This SBIR-Phase 2 protocol will evaluate the two video game interventions designed to change diabetes related…
- Trial name
- NCT00570466
- Testing
- Video Games, Web and DVD knowledge
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes
Avoiding Diabetes After Pregnancy Trial in Moms
Mothers with previous gestational diabetes mellitus (GDM) represent a population at higher risk of future Type 2 diabetes mellitus (T2DM), which is preventable through lifestyle modification.
- Trial name
- ADAPT-M (NCT01918345)
- Testing
- Home-based Physical Activity Program with Health Coach, Home-based Low-GI Diet Program with Health Coach
- Where
- 5 sites in Canada
- Volunteers
- 345 people
- Sponsor
- Women's College Hospital
Prediabetic State
Effectiveness of a Nurse-led Personalized Telephone Intervention on Lifestyle Changes in Diabetes Prevention.
A randomized, 9-months, parallel-group study comparing the effectiveness of a nurse-led telephone personalized lifestyle intervention versus automated SMSs on nutritional and physical activity advice in the reduction of fasting…
- Trial name
- PREDIPHONE (NCT04735640)
- Testing
- nurse-led teleconsultation, SMS
- Where
- Spain
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Metabolic Syndrome
Metabolic Syndrome Risk Factor in IGT: STOP-NIDDM Trial
The aim of the study was to analyse the independent and joint effects of the components of the metabolic syndrome (MetS) on the incidence of diabetes in people with impaired glucose tolerance (IGT) and to assess the effect of…
- Trial name
- NCT00629213
- Testing
- acarbose
- Where
- Germany
- Volunteers
- 1,429 people
- Sponsor
- GWT-TUD GmbH
Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus: New Approaches to Optimize Medical Care in General Practice
Patients with type-2 diabetes mellitus have an higher risk developing secondary disorders. In an epidemiological longitudinal study of about 1.150 patients with type 2 diabetes mellitus we investigate determinants and predictors…
- Trial name
- DIANA (NCT00742547)
- Testing
- Telephone counseling
- Where
- 37 sites in Germany
- Volunteers
- 204 people
- Sponsor
- German Cancer Research Center
Prevention of Developing Type 2 Diabetes
Life Without Diabetes
The aim of the study 'Live - without diabetes' is to investigate the effects of increased physical activity on a daily basis with or without (high intense interval training) HIIT (short and intense: 3 minutes per week) during 12…
- Trial name
- NCT02212665
- Testing
- High intense interval training, Increased daily activity detected by the pedometer, Increased daily activity detected by the pedometer+HIIT
- Where
- Denmark
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Type 2 Diabetes Mellitus (T2DM), Recurrent Urinary Tract Infections
Cranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 Diabetes
The purpose of this prospective, single-arm feasibility study was to evaluate the operational feasibility, tolerability, safety, and exploratory clinical outcomes of an oral supplement combining standardized cranberry…
- Trial name
- NCT07832409
- Testing
- Cranberry Proanthocyanidins and Lactobacilli
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- National Institute of Endocrinology, Georgia
Impaired Fasting Glucose, Impaired Glucose Tolerance
Type 2 Diabetes Mellitus Prevention Ukraine
Development, implementation and evaluation of the effectiveness of lifestyle recommendations for the prevention of type 2 diabetes in rural population of Ukraine
- Conditions
- Impaired Fasting Glucose, Impaired Glucose Tolerance, Type 2 Diabetes
- Trial name
- T2DPUA (NCT04283201)
- Testing
- Physical activity, Macronutrient modification
- Where
- Ukraine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Komisarenko Institute of Endocrinology and Metobolism
Pre-diabetes, Overweight
Genetic Counseling and Lifestyle Change for Diabetes Prevention
This study will examine the impact diabetes genetic counseling on patient motivation and disease prevention behaviors among subjects with pre-diabetes.
- Conditions
- Pre-diabetes, Overweight, Metabolic Syndrome
- Trial name
- GC/LC (NCT01034319)
- Testing
- Diabetes Genetic Counseling, No genetic counseling
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Prediabetes
Prevention of Type 2 Diabetes Mellitus by Changes in Diet
investigators evaluated the efficacy of two types of diet with different macronutrients, on prevention or delaying the onset of type 2 diabetes in subjects with either impaired fasting glucose (IFG) or impaired glucose tolerance…
- Trial name
- NCT02250066
- Testing
- Diet
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Ilam University of Medical Sciences
Type 2 Diabetes Mellitus
Secondary Prevention in Type 2 Diabetes: Comparison of Two Different Resistance Exercise Training Protocols
Skeletal muscle accounts for up to 40% of the total body weight and is responsible for approximately 75% of the whole body insulin-stimulated glucose uptake.
- Trial name
- NCT01218256
- Testing
- Physical exercise training
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Paracelsus Medical University
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC