Clinical trials: Type 2 Diabetes Prevention
Diabetes Mellitus, Type 2
Potential Effectiveness of the Diabetes Prevention Program in the Peri-urban Area of Bamako, Mali
The proposed research is an innovative adaptation of the Centers for Disease Control and Prevention's (CDC) Diabetes Prevention Program "Power to Prevent" program, which will be developed and piloted in the low-income peri-urban…
- Trial name
- PPD-Mali (NCT05260879)
- Testing
- Diabetes prevention program
- Where
- 6 sites in Mali
- Volunteers
- 440 people
- Sponsor
- University Clinical Research Center, Mali
Type 2 Diabetes, Pre-diabetes
Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance
The incidence rate of type 2 diabetes in Thai populations is high and increasing every year. Cardiovascular disease is the main complication of this disease, which has been defined as an important cause of death among Diabetic…
- Conditions
- Type 2 Diabetes, Pre-diabetes, Insulin Resistance, Cardiovascular Risk
- Trial name
- NCT01052025
- Testing
- Curcumin
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1, NAFLD - Nonalcoholic Fatty Liver Disease
Kuwait Adult Diabetes Epidemiological Multidisciplinary (KADEM) Program
Kuwait and the Gulf Region lack large longitudinal studies that identify risk factors dictating the onset of prediabetes and the progression to diabetes.
- Conditions
- Diabetes Mellitus Type 2, Diabetes Mellitus Type 1, NAFLD - Nonalcoholic Fatty Liver Disease, PreDiabetes
- Trial name
- KADEM (NCT06115876)
- Where
- Kuwait
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Obesity, Diabetes Mellitus, Type 2
Multicomponent Intervention on Lifestyle, Anthropometric Measurements, Glycemic Control and Quality of Life in Patients Obese People With Type II Diabetes
The main objective of this study will be to evaluate the effectiveness of a multicomponent intervention on nutritional recommendations and physical activity on glycemic control in obese patients with Type II Diabetes (DM2) in…
- Trial name
- Diabesity (NCT06222775)
- Testing
- Group session 1, Group session 2, Group session 3
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Castilla-La Mancha Health Service
Type 2 Diabetes (T2DM), Obesity & Overweight
Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study
The goal of this pilot clinical trial is to examine how receipt of ingredients for a Mediterranean diet (with or without nutrition classes) impacts Type 2 Diabetes Mellitus risk factors among adults in the US South.
- Trial name
- OLIVE Pilot (NCT07509502)
- Testing
- Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Prediabetic State
Mobile App for Risk Reduction of Type 2 Diabetes
The aim of this feasibility study is to investigate whether a full scale RCT on the efficacy of a mobile app for risk reduction on type 2 diabetes can be conducted in the way it is planned or whether it needs to be modified.
- Trial name
- NCT06117098
- Testing
- Mobile application, Group-based lifestyle intervention at a Healthy Lifestyle Centre + mobile application", Group-based lifestyle intervention
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo Metropolitan University
Type2 Diabetes
Personalized Follow-up Program in the Type 2 Diabetes Prevention
In France, the global prevalence of diabetes was estimated to 5% of the population in 2016, the type two diabetes (DT2) corresponding to 90% of cases.
- Trial name
- PROXIPART (NCT04907760)
- Testing
- Personalized care program
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Coronary Disease, Arteriosclerosis
Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial
The purpose of this study is to determine the effects of low-dose aspirin for the primary prevention of vascular events in patients with type 2 diabetes in Japan.
- Conditions
- Coronary Disease, Arteriosclerosis, Diabetes Mellitus, Type 2
- Trial name
- NCT00110448
- Testing
- Aspirin, No aspirin
- Where
- 2 sites in Japan
- Volunteers
- 2,539 people
- Sponsor
- Kumamoto University
Type 2 Diabetes, Obesity
Prevention of Weight Gain in Adult Patients With Type 2 Diabetes Treated With Pioglitazone
The purpose of the study is to investigate the effectiveness of three lifestyle treatment programs varying in level of intensiveness on prevention of pioglitazone-induced weight gain and to measure the composition of the change…
- Trial name
- NCT00737347
- Testing
- Lifestyle modification
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gestational Diabetes, Type 2 Diabetes
Relationship Between Gestational Diabetes and Type 2 Diabetes
The overall objective of this research project is to study the impact of preventive practices on the T2D-related risk profile among women with and without prior GDM and their children exposed and unexposed to GDM.
- Trial name
- GDM (NCT01340924)
- Where
- Canada
- Volunteers
- 450 people
- Sponsor
- Laval University
Diabetic Foot
Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients
Following a prior observation that a brief structured group educational intervention is effective for the prevention of diabetic foot ulcers in high-risk patients, but that the efficacy decreases over the time, this study is…
- Trial name
- NCT03555656
- Testing
- Repeated intervention, Single session
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Type 2 Diabetes Mellitus
Diabetes in Europe - Prevention Using Lifestyle, Physical Activity and Nutritional Intervention in Catalonia
Public health strategy on type2 diabetes prevention in primary health care. European coordinated project (DE-PLAN) adapted to Catalonia (DE-PLAN-CAT).
- Trial name
- DE-PLAN-CAT (NCT01519505)
- Testing
- Lifestyle intervention
- Where
- Spain
- Volunteers
- 2,082 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Diabetes
Life Style Modifications Prevents Type 2 Diabetes in Asian Indians
Three year prospective randomised controlled trial in IGT subjects to study the effect of metformin and lifestyle modification in preventing the conversion to diabetes
- Trial name
- NCT00279240
- Testing
- Metformin
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.V. Hospital for Diabetes
Diabetes Mellitus, Type 2
Prevention of Type 2 Diabetes Mellitus in Children
This is a pilot study to examine the short-term effects of supervised exercise on metabolic risk factors for type 2 diabetes mellitus in children from a population that is at high risk for this disease.
- Trial name
- NCT00073268
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prediabetic State, Pre Diabetes
Effectiveness of the Brazilian Diabetes Prevention Program
The aim of this multicenter, randomized controlled trial is to assess the effectiveness of the Brazilian Diabetes Prevention Program (delivered face-to-face or via e-health) in preventing type 2 diabetes (T2D) in at least 1,305…
- Trial name
- PROVEN-DIA (NCT06426277)
- Testing
- PROVEN-DIA Hybrid Lifestyle Intervention, Usual Care Lifestyle Guidance, TelePROVEN-DIA Lifestyle Intervention
- Where
- 2 sites in Brazil
- Volunteers
- 1,305 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Type 2 Diabetes
Well-child Visit Video Project
The purpose of this study is to determine if incorporating videos on the importance of minimizing infant sugar-containing beverage (SCB) consumption into well-child visit protocols increases parents' SCB-related knowledge and…
- Trial name
- NCT05011292
- Testing
- Educational Video about SCB, Survey on child feeding and related knowledge and practices, Educational Video other than SCB
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Emory University
Ischemic Stroke, Peripheral Artery Disease
Diabetic Artery Obstruction: is it Possible to Reduce Ischemic Events With Cilostazol?
Investigation of the clinical efficacy and safety of dual antiplatelet therapy with clopidogrel and cilostazol versus clopidogrel alone in preventing ischemic vascular events in patients with type 2 diabetes and symptomatic…
- Conditions
- Ischemic Stroke, Peripheral Artery Disease, Diabetes Mellitus, Type 2
- Trial name
- DORIC (NCT02983214)
- Testing
- Clopidogrel, Cilostazol
- Where
- Greece
- Volunteers
- 826 people
- Sponsor
- University of Ioannina
Type 2 Diabetes, Obesity
Effects of Caloric Restriction in Obesity and Type 2 Diabetes
The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complications in overweight/obese type 2 diabetic…
- Trial name
- CRESO2 (NCT01930136)
- Testing
- Calorie restriction (25%), Ad libitum health diet
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Postprandial Hyperglycemia, Type 2 Diabetes
Development of Anti-Diabetic Nutraceuticals From Legume Seed Coats
This open-label clinical trial aims to evaluate whether daily consumption of soup prepared from boiled water extracts of selected legume seed coats, seasoned with salt and spices, improves glycemic regulation in individuals with…
- Conditions
- Postprandial Hyperglycemia, Type 2 Diabetes, Metabolic Syndromes
- Trial name
- NCT07688694
- Testing
- Legumes seed soup
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- JSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH
Type 2 Diabetes Mellitus, Behavior
Ready to Act - Health Education in People With Hyperglycaemia
A pre-randomized study in primary health care was designed to investigate health education in a subpopulation extracted from general practitioners (GPs) in one Danish county in the treatment arm of the ADDITION…
- Trial name
- NCT01945645
- Testing
- Ready to act
- Where
- Denmark
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of Aarhus