Clinical trials: Type 2 Diabetes Prevention
Gestational Diabetes
Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes
Obese women with history of gestational diabetes are in great danger to develop type 2 diabetes (T2D) within 5-10 years after delivery.
- Trial name
- Liragest (NCT04324229)
- Testing
- Liraglutide 6 MG/ML [Victoza]
- Where
- Finland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Diabetes Mellitus Type 2
Individualized Lifestyle Intervention in Subjects With Prediabetes
The purpose of this prospective randomized multicenter intervention study is to determine whether in the prevention of Diabetes an intensified lifestyle intervention is superior to a conventional lifestyle intervention in high…
- Trial name
- PLIS (NCT01947595)
- Testing
- intensified lifestyle intervention, normal lifestyle intervention, Single lifestyle advice
- Where
- 7 sites in Germany
- Volunteers
- 1,145 people
- Sponsor
- University Hospital Tuebingen
Type 2 Diabetes
Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes
The investigators' general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities…
- Trial name
- iHealth-T2D (NCT02949739)
- Testing
- Intensive lifestyle modification
- Where
- United Kingdom
- Volunteers
- 5,244 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diabete Type 2
Assessment of Personalized Follow-up in Prevention of Type 2 Diabetes
In France, the overall prevalence of diabetes was estimated at 5% of population in 2016, type 2 diabetes (T2DM) corresponding to 90% of cases.
- Trial name
- Proxipart (NCT05325710)
- Testing
- Study nurse intervention
- Where
- France
- Volunteers
- 230 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Diabetic Nephropathy, Diabetic Retinopathy
Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria
This is a prospective, multicenter, randomized, double blind, placebo-controlled and a prospective observational study. This study will be conducted at 15 study centers in various European countries.
- Trial name
- PRIORITY (NCT02040441)
- Testing
- Spironolactone, Standard care
- Where
- 15 sites in Belgium, Czechia and 8 more
- Volunteers
- 1,777 people
- Sponsor
- Peter Rossing
Type2 Diabetes, Life Style
STOP DIABETES - Knowledge-based Solutions
The aim of the Stop Diabetes - Knowledge based solutions (StopDia) consortium project (University of Eastern Finland, National Institute for Health and Welfare, and Technical Research Centre of Finland) is to develop and test…
- Conditions
- Type2 Diabetes, Life Style, Diet Habit, Physical Activity
- Trial name
- StopDia (NCT03156478)
- Testing
- Digital lifestyle intervention group, Combined digital and face-to-face lifestyle intervention group
- Where
- Finland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Type2 Diabetes
PilAm Go4Health Weight Loss Program to Prevent Heart Disease
This is a pilot randomized controlled trial intervention to improve lifestyle behaviors (physical activity and health diet) for Filipino Americans with type 2 diabetes on metformin.
- Trial name
- NCT02290184
- Testing
- PilAm Go4Health Weight-loss Program, Active Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Type 2 Diabetes
Chronotherapy with Low-dose Aspirin for Primary Prevention
Brief summary: Aspirin (ASA) has been shown to provide marked benefits in primary and secondary prevention of cardiovascular events.
- Trial name
- CARING (NCT00725127)
- Testing
- aspirin
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Diabetes Mellitus Type 2, Obesity
Local Measures to Prevent Diabetes in the Værnes Region.
This is a development project involving four different municipalities in Central Norway. The aim is to identify adults with overweight and with an increased risk of developing diabetes mellitus type 2, then to prevent the disease…
- Trial name
- VEND-RISK (NCT01135901)
- Testing
- Behavioural change programme
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Norwegian University of Science and Technology
PreDiabetes, Metabolic Syndrome, Protection Against
Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting
DPPFit is a Healthy Lifestyle Intervention designed to reformat the effective strategies of the Diabetes Prevention Program (NDPP) into a tool for use in a primary care setting.
- Trial name
- DPPFit (NCT04564586)
- Testing
- DPPFit
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Augusta University
Type 1 Diabetes
Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes
In this placebo controlled study the investigators aim to investigate the effects of vitamin D supplementation in subjects with new onset of type 1 diabetes on immunological, endocrine and metabolic parameters.
- Trial name
- NCT01390480
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Medical University of Graz
Obesity
Effectiveness of Individualized Exercise Program, Combined With a Balanced Diet on the Evolution of Body Fat
The purpose of this study is to evaluate the efficacy of 3 of physical exercise training programs, with a supplementation in fruits and vegetables, on body composition.
- Trial name
- LIPOXmax-RUN (NCT01464073)
- Testing
- LIPOXmax, 60% VO2peak, Good Medical Practices
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Gestational Diabetes Mellitus in Pregnancy
The Role of Non-Alcoholic Fatty Liver Disease in Gestational Diabetes
The thought is that Non-Alcoholic Fatty Liver Disease (NAFLD) plays a key role in the progression to prediabetes/T2DM in those with a history of Gestational Diabetes (GDM).
- Trial name
- NCT01855386
- Testing
- Subjects with Gestational Diabetes, Controls without Gestational Diabetes
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Florida
Diabetes Mellitus, Type 2, Heart Failure
Randomised Trial of Health Coaching in Secondary Prevention of Diabetes and Heart Disease
A randomised trial with individual patients as units of observation will be carried out. Health coaching is used to modify health behaviour and thus improve disease control and health status, as well as use of health care…
- Conditions
- Diabetes Mellitus, Type 2, Heart Failure, Coronary Disease
- Trial name
- TerVa (NCT00552903)
- Testing
- Health coaching
- Where
- Finland
- Volunteers
- 1,500 people
- Sponsor
- Paijat-Hame Hospital District
Obese Adults, BMI/Body Composition
Precision Lifestyle Medicine Program for IFHAS Participants
The goal of this clinical trial is to evaluate whether a precision lifestyle medicine intervention can improve cardiometabolic health in Emirati adults aged 25 to 50 years living in Abu Dhabi with obesity (BMI 30-35 kg/m²) who…
- Conditions
- Obese Adults, BMI/Body Composition, Cardiometabolic Risk, Cardiovascular Disease Risk
- Trial name
- NCT07742917
- Testing
- Precision Lifestyle Medicine Program, Standard IFHAS Care
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Institute for Healthier Living Abu Dhabi
Diabetes Mellitus, Type 2, Cardiovascular Disease
Olmesartan Medoxomil in Diabetes Mellitus
This is a study in diabetic patients with at least one additional cardiovascular risk factor and normoalbuminuria prior to randomization.
- Conditions
- Diabetes Mellitus, Type 2, Cardiovascular Disease, Kidney Disease
- Trial name
- NCT00185159
- Testing
- Olmesartan medoxomil
- Where
- Germany
- Volunteers
- 4,449 people
- Sponsor
- Sankyo Pharma Gmbh
Type 2 Diabetes, Obesity
Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment
The purpose of this study was to evaluate the effectiveness of a school-to-home education program for it's ability to increase knowledge about, and ability to prevent type two diabetes in children and parents.
- Trial name
- DvtENERGY (NCT00542113)
- Testing
- DvtProgram ENERGY, DvtProgramENERGY
- Where
- 2 sites in United States
- Volunteers
- 1,703 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Type 2 Diabetes
Personalised Exercise Training in Adolescents With Type 2 Diabetes for the Early Prevention of Beta Cell Dysfunction
Exercise training is a key component in the prevention and treatment of various chronic diseases such as Type 2 diabetes (T2DM). Adaptations and effects that occur with exercise training differ according to exercise protocols.
- Trial name
- PT4DEEP (NCT05344768)
- Testing
- aerobic exercise, high-intensity interval exercise training, resistance exercise training
- Volunteers
- 120 people
- Sponsor
- Yasemin Çırak
Diabetes Mellitus, Diabetes Mellitus, Type 2
A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program
A pilot study titled "A Virtual Cardiometabolic Health Program for African Immigrants (The Afro-DPP Program) will be conducted to address the cardiometabolic of community-dwelling African immigrants who have multiple…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension
- Trial name
- NCT05144737
- Testing
- The Diabetes Prevention Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2, PreDiabetes
The Effect of 360 Video and MAPS on Enrollment in the DPP
We will conduct a three-armed randomized, clinical trial to test the incremental effectiveness of Mobile 360° Video and Motivation and Problem Solving in motivating individuals with Prediabetes to enroll in the Diabetes…
- Trial name
- NCT04746781
- Testing
- Mobile 360° Video intervention, Motivation and Problem Solving (MAPS), Risk notification/education
- Where
- United States
- Volunteers
- 818 people
- Sponsor
- University of Utah