Clinical trials: Type 2 Diabetes Prevention
Prediabetes
Prevention of Type 2 Diabetes With Vitamin D Supplementation
PREVENT-WIN study has three components. The work plan will have the following S\&T components. Component 1: Cross-sectional Study Cross-sectional study will be of 1.5 years where 400 women from rural will be screened randomly for…
- Trial name
- PREVENT-WIN (NCT02513888)
- Testing
- vitamin D + diet and lifestyle
- Where
- India
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Type 2 Diabetes
Prevention of Heart Failure in Type 2 Diabetes by Exercise Intervention
Global longitudinal strain emerged as an important predictive marker that could be assessed during echocardiography. It enabled the detection of subclinical myocardial systolic dysfunction, without observable reductions in…
- Trial name
- PROTECTION (NCT05023538)
- Testing
- Cycling
- Where
- 2 sites in Belgium
- Volunteers
- 182 people
- Sponsor
- Hasselt University
Diabetes
Study of a Postpartum Diabetes Prevention Program for Hispanic Women
The overall goal of this randomized controlled trial is to test the efficacy of a culturally and linguistically modified, individually-tailored lifestyle intervention to reduce risk factors for type 2 diabetes and cardiovascular…
- Trial name
- NCT01679210
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Cardiovascular Diseases, Diabetes Mellitus Type 2
"Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"
This study aims to test the feasibility of a new systematic screening program to allow the early detection of individuals aged 50 years at risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) in the resident…
- Trial name
- JAC_AST (NCT07344701)
- Testing
- Screening program
- Where
- 2 sites in Italy
- Volunteers
- 2,951 people
- Sponsor
- Marche Region Regional Health Agency
Diabetes Mellitus, Type 2, Obesity
Lifestyle Modification for Type 2 Diabetes Prevention in Overweight Youth
The number of youth with Type 2 diabetes (T2D) is rising in the population, which is a concerning public health trend. There has been little research testing ways to prevent the development of this disease in children who are at…
- Trial name
- NCT01610219
- Testing
- Lifestyle Modification for Type 2 Diabetes Prevention, Nutrition and Physical Activity
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetes Mellitus Type 2
CDRM Study: Computer-assisted Diabetes Risk Management-for Secondary and Tertiary Prevention of T2DM Complications
The CDRM study will evaluate a newly developed approach to improve management and secondary prevention in diabetes care. The research will explore the impact of an medical care intervention via a computer-assisted diabetes risk…
- Trial name
- CDRM_DMP (NCT01556529)
- Testing
- risk profile information, standard DMP care
- Where
- Germany
- Volunteers
- 405 people
- Sponsor
- Philipps University Marburg
Diabetes Mellitus, Type 2, Coronary Artery Disease
SGLT-2 Inhibitors in Prevention of Post-procedural Renal and Cardiovascular Complications aFter PCI Among Patients With Diabetes Mellitus and Coronary Artery Disease: a Prospective, Randomized, Pilot Study (SAFE-PCI)
Patients with type 2 diabetes mellitus (DM) have higher risk of major cardiovascular events (MACE) and renal disfunction. The Sodium-glucose cotransporter-2 inhibitors (iSGLT2) reduces hyperglycemia in patients with type 2 DM and…
- Conditions
- Diabetes Mellitus, Type 2, Coronary Artery Disease, Acute Kidney Injury
- Trial name
- SAFE-PCI (NCT05037695)
- Testing
- empagliflozin 25 MG
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Type 2 Diabetes Mellitus, Prediabetes
Effect of Iron Reduction by Phlebotomy for Type 2 Diabetes
High tissue iron is a risk factor for diabetes even within the broad normal range of normal human values. In order to demonstrate the benefits of reducing iron on glucose homeostasis and to better define the parameters for larger…
- Trial name
- NCT02468037
- Testing
- Phlebotomy
- Volunteers
- 12 people
- Sponsor
- University of Utah
Prediabetes, Type 2 Diabetes (T2DM)
Vitamin D and Type 2 Diabetes - Treat-To-Target
This study tests whether taking a weekly dose of vitamin D, with the dose adjusted to reach a target blood vitamin D level, can help control blood sugar levels in adults at high risk of developing type 2 diabetes (prediabetes).
- Trial name
- D2d-TTT (NCT07448974)
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Tufts Medical Center
Overweight, Obesity
PROTeIn-rich Meals to Control Glucose
The overall aim is to identify the dietary pattern for prevention and treatment of type 2 diabetes. The specific aim of this pilot project is to compare effects of two diets with different diurnal distribution of carbohydrates…
- Conditions
- Overweight, Obesity, Prediabetes, Type 2 Diabetes
- Trial name
- PROTIME (NCT06382480)
- Testing
- Diet with specific macronutrient composition.
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- German Institute of Human Nutrition
Type 2 Diabetes, Pre-Diabetes
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
The goal of this study is to address the risk of diabetes among men by creating a Diabetes Prevention Program (DPP) tailored to men.
- Trial name
- Power-Up (NCT04104243)
- Testing
- Men-Tailored DPP (Power-Up)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Albert Einstein College of Medicine
Cardiovascular Diseases, Type 2 Diabetes
Primary Prevention With the Lifestyle Tool
In this study participants will be randomized to use a digital lifestyle tool over three years or to a control group without access to the tool.
- Trial name
- NCT05309850
- Testing
- Lifestyle tool
- Where
- Sweden
- Volunteers
- 90,000 people, healthy volunteers welcome
- Sponsor
- Region Skane
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Type 2 Diabetes Mellitus ;Obesity,High Triglycerides；TCM
Chinese Medicine Treatment of Obesity With Type 2 Diabetes, Dyslipidemia
With metformin for the control, evaluate the safety and efficacy of Jiangtangtiaozhi decoction in treatment of obesity with type 2 diabetes, dyslipidemia
- Trial name
- NCT01471275
- Testing
- Metformin, Jiangtangtiaozhi decoction
- Where
- 8 sites in China
- Volunteers
- 450 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Type 2 Diabetes Mellitus
Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium Hydrochloride and Berberine on lowering glucose in patients with type 2 diabetes mellitus and to detect the potential mechanism.
- Trial name
- NCT02084004
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
Type 1 Diabetes, Hypoglycemia
Pen-Administered Low-Dose Dasiglucagon for Prevention and Treatment of Hypoglycemia in People With Type 1 Diabetes
The aim of the study is to evaluate the efficacy, safety and feasibility of outpatient-utilization of low-dose dasiglucagon administered via a multi-dose reusable pen injector in preventing and treating mild hypoglycemia in…
- Trial name
- NCT04764968
- Testing
- Dasiglucagon
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Steno Diabetes Center Copenhagen
Impaired Glucose Tolerance
Vitamin D for the Prevention of Diabetes Type 2
The prevalence of type 2 diabetes is increasing, which for most societies has considerable consequences not only regarding health but also economy.
- Trial name
- NCT00685594
- Testing
- cholecalciferol
- Where
- Norway
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Type 2 Diabetes Mellitus
Tertiary Prevention in Type II Diabetes Mellitus in Canary Islands Study
Objective: To improve health outcomes of patients with type 2 diabetes mellitus (T2DM) by influencing disease self-management through lifestyle modification and by helping primary care professionals to improve health care…
- Trial name
- INDICA (NCT01657227)
- Testing
- Intervention to patients, Intervention to professionals, Usual care
- Where
- Spain
- Volunteers
- 2,334 people
- Sponsor
- Servicio Canario de Salud
Diabetes Mellitus, Type 2
Call-2-Health: Preventing Type II Diabetes
It is estimated that 30 million U.S. adults will have type 2 diabetes by 2050. Contributing to this national trend is the obesity epidemic.
- Trial name
- C2H (NCT01827826)
- Testing
- Telephonic intervention to prevent Diabetes Mellitus, Type 2
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente