Clinical trials: Type 2 Diabetes Prevention
Diabetes Mellitus, Type 2
Diabetes Prevention Programming for Women With a History of Gestational Diabetes
The purpose of this study is to offer women with a history of gestational diabetes access to diabetes prevention programming; their children 10 and older can participate.
- Trial name
- NCT03971838
- Testing
- Positive Outcomes for Women
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Indiana University
Pre Diabetes, Obesity
Community Based DPP Program for Hispanic/Latino Females
Is well known that obesity is increasing in the United States (US) and particularly among Hispanic/ especially in in socially disadvantaged groups.
- Trial name
- NCT04052815
- Testing
- Diabetes prevention program culturally tailored
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loyola University
Pre-diabetes
More Health Less Diabetes
The "More Health, Less Diabetes" project is a hybrid randomized controlled trial to prevent type 2 diabetes in individuals at risk through structured exercise and lifestyle education.
- Trial name
- MHLD (NCT07079722)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Lactose Intolerance, Lactose Intolerant
Milk for Diabetes Prevention
Individuals with lactase non-persistence (LNP; determined by a functional variant in the LCT gene [rs4988235, GG genotype]) are susceptible to lactose intolerance in adulthood due to deficiency of lactase, the enzyme which…
- Conditions
- Lactose Intolerance, Lactose Intolerant, Lactase Persistence, Pre-Diabetes
- Trial name
- NCT06513026
- Testing
- Lactose-Containing Milk, Lactose-Free Milk
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Albert Einstein College of Medicine
Type 2 Diabetes
Taking Action Together- A Diabetes Prevention Program
The purpose of this study was to determine whether once-weekly exposure to a program that fostered self-esteem building, and improvements in nutrition and physical activity behaviors would reduce risk of type 2 diabetes in…
- Trial name
- TAT (NCT01039116)
- Testing
- High Intensity, Low Intensity
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, Berkeley
Obesity, Type 2 Diabetes
Probiotics as a Novel Approach to Modulate Gut Hormone Secretion and Risk Factors of Type 2 Diabetes and Complications
The investigators aim to test the hypothesis that Lactobacillus Reuteri-enriched microbiota improves insulin sensitivity and glucose tolerance in obese healthy and obese type 2 diabetes patients by improving gut hormone secretion…
- Trial name
- NCT01250106
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Type 2 Diabetes
Diabetes Prevention in Clinical Practice.
We randomize individuals with impaired glucose tolerance to one of three arms for degree of physical activity: 1. Continue with your current life style; 2. Ordinary life activities for increased physical activity; 3.
- Trial name
- DIAVIP (NCT01834378)
- Testing
- Low intensity intervention, High intensity intervention.
- Volunteers
- 96 people
- Sponsor
- Göteborg University
Diabetes Mellitus, Schizophrenia
Diabetes Prevention Program in Schizophrenia [DPPS]
Diabetes is 2-5 times more common in schizophrenia and it is a preventable; but the current diabetes prevention guidelines are not suitable for implementation in the severely mentally ill population.
- Trial name
- NCT00182494
- Testing
- Modified diabetes prevention protocol & Metformin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Hamilton Health Sciences Corporation
Diabetes Mellitus, Type 2, Obesity
Impact of a Regional Program Agir Sur Sa SantE
The prevention and control of lifestyle-related non-communicable chronic diseases, including diabetes, obesity and cardiovascular disorders, that share common risk factors, has now become a major focus of the World Health…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- NCT02478853
- Testing
- Implementation of a new regional care framework
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus, Type 2
Long-term Study of Nateglinide+Valsartan to Prevent or Delay Type II Diabetes Mellitus and Cardiovascular Complications
This study is a test of the safety and effectiveness of two drugs, one for diabetes and one for hypertension, in keeping patients with high lab values of glucose from progressing to frank diabetes and developing cardiovascular…
- Trial name
- Navigator (NCT00097786)
- Testing
- Valsartan 160 mg + nateglinide 60 mg
- Where
- 38 sites in United States, Argentina and 36 more
- Volunteers
- 9,306 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes, Obesity
Lifestyle Intervention in Obese Non-diabetic Adults With a Family History of Diabetes.
The aim of this study is to investigate weather gradual weight loss achieved with healthy lifestyle changes influence hormonal factors affecting appetite and blood glucose control in obese people without presence of diabetes.
- Trial name
- NCT00993603
- Testing
- 8-month group lifestyle programme
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Royal Bournemouth Hospital
Diet, Food and Nutrition
Metabolomics-Driven Insights Into Ultra-Processed Foods
The goal of this dietary intervention study in generally healthy adults is to develop new ways to use blood samples to measure the common types of highly processed foods and beverages that people eat on a regular basis.
- Trial name
- NCT07717970
- Testing
- UPF Test Diet A: Starchy, refined grains, UPF Test Diet B: Meat, fish, and bread products, UPF Diet C: Dairy products, including cheese and cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Prediabetes / Type 2 Diabetes
Health Assessment of Low Glycaemic Index - High Protein Rice to Enhance Glycemic Control Through Nutrition
Type 2 Diabetes (T2D) represents a critical public health challenge in Singapore, with prevalence projected to reach one million residents by 2050.
- Trial name
- HARVEST (NCT07663123)
- Testing
- Functional rice variaties
- Volunteers
- 225 people
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Diabetes Mellitus, Type 2
BeWell24: Smartphone-based Diabetes Prevention in the VA
Type 2 diabetes (T2D) is a national epidemic and current lifestyle programs and medications are not effectively managing the crisis.
- Trial name
- NCT03202277
- Testing
- BeWell24 smartphone app, Health education app
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Arizona State University
PreDiabetes
The YMCA Healthy Lifestyle Program for Prediabetes
The goal of this 26 week randomized controlled clinical trial is to learn if using a real time continuous glucose monitor (CGM) in a healthy lifestyle program for adults with prediabetes at the YMCA can improve glucose levels…
- Trial name
- Y-HELP (NCT06841796)
- Testing
- Real time continuous glucose monitor (Stelo)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Young Men's Christian Association of the Blue Water Area
Type 2 Diabetes Mellitus
Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes
Gestational diabetes is also a strong risk factor for the development of diabetes mellitus at a later stage of life in previous GDM woman.
- Trial name
- NCT00265746
- Testing
- Metformin, Lifestyle intervention - diet, physical activity
- Sponsor
- Medical University of Lodz
Hypertension, Diabetes Mellitus, Type 1
Community Models for Hypertension and Diabetes Care for Refugees
The project will investigate and improve a community health worker (CHW) based model for non-communicable disease (NCD) care in a humanitarian emergency.
- Conditions
- Hypertension, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Comorbidities and Coexisting Conditions
- Trial name
- NCT04229667
- Testing
- Improved Community Health Volunteer (CHV) program
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Rescue Committee
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Diabetes Prevention Among Post-partum Women With History of Gestational Diabetes
The purpose of the STAR-MAMA intervention is to develop a patient-tailored telephone-base counseling intervention for young Latino women who are at high risk of diabetes.
- Trial name
- Star-Mama (NCT02240420)
- Testing
- Life Style Counseling (Star-Mama)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, San Francisco
Postoperative Delirium (POD)
Intranasal Insulin for Postoperative Delirium in Older Patients With T2DM
Postoperative delirium (POD) is highly prevalent in older patients with type 2 diabetes mellitus (T2DM). Cerebral insulin resistance is considered a key pathophysiological mechanism underlying this association.
- Trial name
- NCT07720479
- Testing
- Insulin, human
- Volunteers
- 210 people
- Sponsor
- Weidong Mi
Prediabetic State, Life Style
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
Nearly half of adults in the United States have or are at risk of developing type 2 diabetes. The overall goal of this community-engaged research is to examine the efficacy of an innovative couple-based lifestyle intervention to…
- Conditions
- Prediabetic State, Life Style, Intervention Study, Social Support
- Trial name
- PT2T (NCT06690788)
- Testing
- Individual intervention condition (PreventT2), Couple-based intervention condition (PreventT2 Together; couple-based adaptation of 2021 PreventT2; approved by the CDC in November 2022 as an Alternate Curriculum for use in the NDPP)
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Utah