Clinical trials: Type 2 Diabetes Prevention
PreDiabetes, Prediabetic State
Small Steps for Big Changes - Recipe for Health
The purpose of this study is to evaluate changes in HbA1c levels, diet, weight and waist circumference in Small Steps for Big Changes (SSBC) diabetes prevention program participants two year after program completion compared to…
- Trial name
- RFH (NCT05962983)
- Testing
- Small Steps for Big Changes Program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of British Columbia
Type 2 Diabetes
High-amylose Barley (HIAMBA) in the Regulation and Prevention of Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of naturally produced high-amylose barley (Lean-baking barley®) on the postprandial glucose-metabolism in subjects…
- Trial name
- NCT04702672
- Testing
- 100% wheat (control), 100% Lean-baking barley®, 100% regular barley
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 2 Diabetes, Arteriosclerosis
PräVaNet - Structured, Intersectoral, Multiprofessional, Digitized Program to Optimize Cardiovascular Prevention
PräVaNet is a prospective, 1:1 randomized, controlled trial to investigate the efficacy of a new, digitalized prevention strategy ("ePrevention") in cardiovascular high-risk patients with type 2 diabetes mellitus in the…
- Conditions
- Type 2 Diabetes, Arteriosclerosis, Arterial Hypertension, Lipid Metabolism Disorders
- Trial name
- PräVaNet (NCT05887180)
- Testing
- PräVaNet-Intervention
- Where
- Germany
- Volunteers
- 209 people
- Sponsor
- Charite University, Berlin, Germany
Diabetes Mellitus, Type 2, Family Health
Family-based Prevention of Diabetes Through Eating Habits and Physical Activity
Introduction: Type 2 diabetes represents a growing health risk for the society. An easy-access and low-cost intervention for the whole family will be developed to help families with (at risk of) type 2 diabetes maintain…
- Conditions
- Diabetes Mellitus, Type 2, Family Health, Health Behavior, Healthy Lifestyle
- Trial name
- GO_EASY (NCT05694351)
- Testing
- Healthy meals and physical activity in families with type 2 diabetes
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Slagelse Hospital
Pre-Diabetes, Metabolic Syndrome
Integrating Lifestyle Therapy for Diabetes Prevention Into Primary Care
An educational intervention in the General Medicine Clinic aimed at both primary care providers (PCPs) and their patients with metabolic syndrome/pre-diabetes (MetSyn/PDM).
- Conditions
- Pre-Diabetes, Metabolic Syndrome, Type 2 Diabetes
- Trial name
- NCT00853801
- Testing
- Lifestyle intervention and provider feedback
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Cook County Health
Diabetes Mellitus, Type 2, PreDiabetes
iCan Diabetes Self-management and Prevention Program
The purpose of this study is to test the feasibility and preliminary efficacy of the iCan Diabetes Self-Management and Prevention Support Group using a single arm clinical trial.
- Trial name
- NCT05571436
- Testing
- iCan Diabetes Self-management and Prevention Support Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Cardiovascular Diseases, Cardiovascular Risk Factor
The Use of Icosapent Ethyl on Vascular Progenitor Cells in Individuals With Elevated Cardiovascular Risk
IPE-PREVENTION is a prospective, randomized, 3-month long, open-label study. A total of 70 individuals with elevated cardio-metabolic risk and heightened triglyceride levels, and who are on stable statin therapy will be…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Triglycerides High, Diabetes Mellitus, Type 2
- Trial name
- IPE-PREVENTION (NCT04562467)
- Testing
- Icosapent Ethyl 1000 MG Oral Capsule [Vascepa]
- Where
- 3 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Obesity
Study of Impact of Behavioral Intervention- Exercise, Nutrition, Education- on Body Mass Index (BMI)
This study will evaluate the impact a behavioral intervention can have on BMI. The researchers anticipate the intervention group will experience a decrease in BMI of approximately five points.
- Trial name
- NCT00132132
- Testing
- Behavioral education program
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Lymphoma, Diabetes Mellitus, Type 2
Validation of Insulin Protocol for Glucocorticoid-induced Hyperglycemia in Diabetic Oncology Patients
There are no guidelines for the management of glucocorticoid- (henceforth steroid) induced elevated blood sugars (henceforth hyperglycemia).
- Conditions
- Lymphoma, Diabetes Mellitus, Type 2, Hyperglycemia
- Trial name
- NCT02012465
- Testing
- Insulin protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes (T2DM)
Implementing WHO HEARTS-D Guidelines in Bangladesh for Diabetes Control and Prevention
Type-2 diabetes (T2D) is rising at an alarming rate in the low- and middle-income countries (LMIC). This rapid increase in the T2D burden has a particular impact on cities, where more than half the LMIC populations currently live…
- Trial name
- T2D IR (NCT07155902)
- Testing
- The community-to-facility integrated strategy
- Volunteers
- 5,000 people
- Sponsor
- Florida International University
Diabetes Mellitus, Type 2, PreDiabetes
Sardine-enriched Diet for Prevention Type 2 Diabetes
The hypothesis formulated is that 200 g of sardine on a weekly basis will have a favourable impact avoiding the natural development of the pathology due to changes in the biochemical profile, the anthropometrics, inflammatory…
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Diet Habit, Diabetes
- Trial name
- NCT03557541
- Testing
- Sardine, Control
- Where
- Spain
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Overweight Children With Type 2 Diabetes Risk
Prevention of Diabetes in Overweight/Obese Preadolescent Children
Background: The global pandemic obesity has led to increased risk for prediabetes and type 2 diabetes (T2D). Objectives: (i) To evaluate the effect of a 22 weeks multidisciplinary intervention program including exercise on T2D…
- Trial name
- PREDIKID (NCT03027726)
- Testing
- lifestyle and psycho-educational program, Exercise plus lifestyle and psycho-educational program
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of the Basque Country (UPV/EHU)
PreDiabetes, Insomnia
Cognitive Behavioral Sleep Intervention for Prevention of Type 2 Diabetes
The proposed study aims to evaluate if improving sleep could enhance the intensive lifestyle intervention for improving weight loss and glycemic control in prediabetic individuals who have insomnia with short sleep duration.
- Conditions
- PreDiabetes, Insomnia, Sleep Deprivation
- Trial name
- NCT04457440
- Testing
- Intensive Lifestyle Intervention, Intensive Lifestyle Intervention enhanced with Cognitive Behavioral Sleep Intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 36 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Type 2, Prediabetic State
PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment
The PRuDENTE study proposes to assess if metformin therapy a viable, efficient and cost-effective intervention to decrease the incidence of type 2 diabetes (DMT2) in adult subjects with obesity and pre-diabetes in Mexico City.
- Trial name
- PRuDENTE (NCT03194009)
- Testing
- Metformin, Lifestyle intervention
- Where
- Mexico
- Volunteers
- 3,060 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Type 2 Diabetes
P4 Approach in Diabetes Type 2
The study aims to assess the impact of the P4 approach on established markers of glucose metabolism in type 2 diabetics. Secondary objectives are examination of the changes in physical characteristics, quality of life and the…
- Trial name
- P4P-Hillegom (NCT02196350)
- Testing
- Intervention A: Diet, Intervention B: Exercise, Intervention C: Diet and Exercise
- Where
- 9 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- W.J. Pasman
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 2
Health Mindset as a Driver of Efficacy of a Diabetes Prevention Program in the Blackfeet Community
The overall goal of this project is to understand whether the established Diabetes prevention program works to reduce diabetes risk by shifting mindsets about health.
- Trial name
- NCT04571723
- Testing
- Diabetes Prevention Program, Health Mindset modified diabetes prevention program
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Montana State University
PreDiabetes
Precision Medicine for Preventing Type 2 Diabetes: a Step Forward
The prevalence of type 2 diabetes (T2D) has been rising rapidly with an increased burden to the healthcare system. As such T2D prevention is highly recommendable, and, theoretically, it can definitely be successful.
- Trial name
- PRE-MED2 (NCT05147961)
- Testing
- Digital Health, Standard care
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Diabetes Mellitus, Type 2, Hypertension
TRANSforming InTerprofessional Cardiovascular Prevention in Primary Care
The TRANSIT program is a program to TRANSform InTerprofessional clinical practices to improve cardiovascular prevention in primary care.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Dyslipidemias, Cholesterol, LDL
- Trial name
- TRANSIT (NCT01418716)
- Testing
- Facilitation, Passive diffusion
- Where
- Canada
- Volunteers
- 759 people
- Sponsor
- Fonds de la Recherche en Santé du Québec