Clinical trials: Type 2 Diabetes Risk
Type 2 Diabetes, Obstructive Sleep Apnea (OSA)
Screening for Obstructive Sleep Apnea in High-risk Patients in a Danish Rural Population: A Pilot Feasibility Study
Background: Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent collapse of the upper airway during sleep, resulting in intermittent hypoxia and fragmented sleep.
- Trial name
- NCT07778121
- Testing
- Home Sleep Apnea Test
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Diabetes Mellitus, Non-Insulin-Dependent, Glucose Intolerance
Diabetes Prevention Program
The Diabetes Prevention Program is a nationwide clinical study to answer the question: Can Type 2 diabetes (also called noninsulin-dependent or adult-onset diabetes) be prevented or delayed? The study has recruited volunteers…
- Trial name
- NCT00004992
- Testing
- Intensive lifestyle, Metformin
- Where
- United States
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus
Impact of Self-care Education Program in Patients With Type 2 Diabetes in Primary Care in the Basque Country
Main objective:To evaluate the effectiveness of the "Diabetes Self-Management Programme" (DSMP) on the metabolic control, cardiovascular risk reduction, quality of life and self-efficacy in adult patients with type 2 diabetes…
- Trial name
- NCT01642394
- Testing
- Diabetes Self-Management Program
- Where
- Spain
- Volunteers
- 594 people
- Sponsor
- Osakidetza
Cardiovascular Diseases, Hypercholesterolemia
The Combined Portfolio Diet and Exercise Study
The purpose of this study is to determine whether a dietary portfolio of cholesterol-lowering foods (viscous fibres, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA)…
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- PortfolioEx (NCT02481466)
- Testing
- Portfolio diet and structured exercise, DASH-like diet and structured exercise, Portfolio diet and routine exercise
- Where
- 4 sites in Canada
- Volunteers
- 232 people
- Sponsor
- Unity Health Toronto
Obesity, Mild, Obesity, Morbid
Predictors of Bariatric Surgery Weight Loss
The aim of the observational cross-sectional study is to determine the prevalence and correlates of disordered eating among candidates for bariatric surgery in the BariPredict cohort.
- Conditions
- Obesity, Mild, Obesity, Morbid, Diabete Mellitus, Diabetes Mellitus, Type 2
- Trial name
- BariPredict (NCT06480058)
- Where
- Kuwait
- Volunteers
- 376 people
- Sponsor
- Kuwait University
Pediatric Obesity, Type 2 Diabetes
A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in Children
The purpose of this study was to determine if a family-focused lifestyle intervention helps to improve the health status, behaviors, and adjustment of overweight children.
- Conditions
- Pediatric Obesity, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- FBI (NCT01146314)
- Testing
- Family Focused Lifestyle Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Nemours Children's Clinic
Insulin Sensitivity, Lipid Metabolism
Effects of Potato Resistant Starch Intake on Insulin Sensitivity, Related Metabolic Markers and Satiety
The objective of this study is to assess whether intake of baked and then chilled potatoes over a 24-h period, compared to intake of isocaloric, carbohydrate (CHO)-matched foods low in fiber and resistant starch (RS), will…
- Conditions
- Insulin Sensitivity, Lipid Metabolism, Resistant Starch, Potato
- Trial name
- NCT03689738
- Testing
- Potato (Resistant Starch), CHO-matched (Low-fiber, RS-free)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Diabetes Mellitus, Type 2, Hypoglycemia
Safer Aging With Diabetes Monitoring
Older adults with type 2 diabetes are at higher risk for severe hypoglycemia and its related complications (including hospitalization and death) when taking insulin.
- Trial name
- SAGE (NCT06296485)
- Testing
- SAGE Group Sessions, Usual Care
- Where
- 6 sites in United States
- Volunteers
- 360 people
- Sponsor
- Kaiser Permanente
Type 2 Diabetes Mellitus
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes mellitus using metformin.
- Trial name
- NCT00097500
- Testing
- exenatide, Insulin glargine, Metformin
- Where
- 3 sites in Finland, Netherlands and 1 more
- Volunteers
- 69 people
- Sponsor
- AstraZeneca
Prediabetes / Type 2 Diabetes
Diabetes Prevention in Hispanic Adults Using Constant Glucose Monitors
The purpose of the study is twofold: to see the impact of your environmental stress on daily glucose changes and to create an intervention using CGM to potentially decrease risk for diabetes.
- Trial name
- NCT06864728
- Testing
- Video Diabetes Education, In person or virtual diabetes education
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas at Austin
Type 2 Diabetes Mellitus (T2DM), Atherosclerosis
Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes
Patients with type 2 diabetes and cardiovascular risk factors are at increased risk of cardiovascular events. Therefore, a multi-center prospective randomized study will be conducted to compare the efficacy and safety of…
- Trial name
- Cilo-Asa (NCT07719894)
- Testing
- Cilostazol, Aspirin
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Seoul National University Bundang Hospital
Acute Coronary Syndrome, Type 2 Diabetes
A Phase 2 Study to Determine the Effects of BXT-51072 in Diabetic Patients Undergoing Angioplasty (PCI)
The purpose of this study is to determine the safety and feasibility of BXT-51072 as a cardioprotective agent in diabetics undergoing elective angioplasty / percutaneous intervention (PCI), a procedure to "open" coronary…
- Trial name
- NCT00320502
- Testing
- BXT-51072
- Where
- 4 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Synvista Therapeutics, Inc
Atherosclerosis, Cardiovascular Disease
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab compared with placebo in adults who have elevated hsCRP and at increased…
- Conditions
- Atherosclerosis, Cardiovascular Disease, Obesity, Hypertension
- Trial name
- CLARITY-CRP (NCT07783802)
- Testing
- Clazakizumab
- Where
- 46 sites in United States, Argentina and 2 more
- Volunteers
- 120 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
Freestyle Libre and Hospital Admissions in Type 2 Diabetes
This study aims to investigate the utility of a combination of structured nurse led intervention and the use of Freestyle libre in adults with type 2 diabetes who have suffered an episode of severe hypoglycaemia in terms of…
- Trial name
- STRATUS (NCT04997512)
- Testing
- Freestyle libre, Nurse led structured intervention - hypoglycaemia education and diabetes treatment modification modification
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Leeds
Discriminate Obese Children at Risk for Diabetes.
Circulating microRNAs for Discriminating Obese Preschoolers at Risk of Diabetes
Childhood obesity certainly increases susceptibility to type 2 diabetes (T2D) in adulthood. Recently, microRNAs (miRNAs) are closely related to various diseases and have been suggested as valuable biomarkers.
- Trial name
- NCT02843139
- Where
- China
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Type 2 Diabetes Mellitus
Exenatide Once Weekly, Cardiovascular Risk and Type-2 Diabetes
The glucagon-like peptide 1 (GLP-1) agonist exenatide represents an effective therapy in patients with type 2 diabetes mellitus (T2DM), which also seems to have some important non-glycemic effects.
- Trial name
- NCT02380521
- Testing
- Exenatide once weekly (BYDUREON™)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Palermo
Aerobic Exercise, Strength Training
Home-Based Circuit Training in Overweight/Obese Older Adult Patients With Knee Osteoarthritis and Type 2 Diabetes
Background: Obesity and type 2 diabetes mellitus (T2DM) are considered two of the most prevalent metabolic diseases linked to the onset of knee pain caused by osteoarthritis.
- Conditions
- Aerobic Exercise, Strength Training, Glycemic Control, Blood Pressure
- Trial name
- NCT06309654
- Testing
- 12-week home-based circuit training (HBCT), Standard of care (CONT)
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Low Density Lipoprotein Cholesterol Goal Achievement
of PATient Education Related to CV Risk factOrs in Type 2 Diabetes Mellitus(Patrol).
An observational, non-interventional, multi-centre study to provide further information on the utility of test for a predictive marker by investigating the current prevalence of high sensitivity CRP (hs-CRP) testing and…
- Trial name
- DART (NCT00925717)
- Where
- 22 sites in South Korea
- Volunteers
- 4,045 people
- Sponsor
- AstraZeneca
Overweight, Glucose Intolerance
Diabetes Prevention In Estrie
This study compared the efficacy at one year of an interdisciplinary approach including individual counseling and group seminars versus group seminars alone to induce weight loss in subjects at high risk of developing type 2…
- Trial name
- NCT00991549
- Testing
- interdisciplinary intervention or meeting-seminars
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus Type 2, Sarcopenia
A Theory-based Home-based Multi-component Exercise Training Among Older Adults With Type 2 Diabetes Mellitus
The goal of this clinical trial is to learn if a theory-based home-based multi-component exercise training works to prevent sarcopenia in older adults with type 2 diabetes mellitus.
- Trial name
- NCT06393244
- Testing
- a theory-based home-based multi-component exercise training
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cheng Li