Clinical trials: Type 2 Diabetic Kidney Disease
Renal Insufficiency and Diabetes Mellitus
Prevention of Renal Failure in People Followed for Type 2 Diabetes in General Practice
This work will make it possible to identify the nephron loss of type 2 diabetic patients in the western region and to better define in general practice the impact of the elements put in place to reduce this loss and to raise…
- Trial name
- PENEDIAB (NCT05749679)
- Testing
- training and audit, Routine care
- Volunteers
- 360 people
- Sponsor
- University Hospital, Lille
Type 2 Diabetes With Renal Manifestations
Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals
Predictors of Chronic Kidney Disease among Type 2 Diabetic Patients in Assiut University Hospitals.
- Trial name
- Ckd&dm (NCT05847400)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Diabetic Nephropathies
Effect of Low Protein Diet in Preventing the Progression of Diabetic Nephropathy
Diabetic nephropathy is the leading cause of chronic kidney disease all the world in spite of progress in new treatment for diabetes and anti hypertensive drugs.
- Trial name
- LPD (NCT00448526)
- Testing
- low protein diet
- Sponsor
- Kanazawa Medical University
Diabetes Mellitus, Type 2
Study to Assess the Optimal Renoprotective Dose of Aliskiren in Hypertensive Patients With Type 2 Diabetes and Incipient or Overt Nephropathy
This study will assess the optimal renoprotective dose of Aliskiren in hypertensive type 2 diabetes patients with incipient or overt nephropathy
- Trial name
- NCT00464776
- Testing
- Aliskiren
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Novartis
Type 2 Diabetes, Microvascular Function
The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes
Patients with type 2 diabetes have an increased risk of developing vascular complications. Microvascular dysfunction might be caused by the increased production of methylglyoxal under hyperglycaemic conditions.
- Conditions
- Type 2 Diabetes, Microvascular Function, Retinopathy, Diabetic, Nephropathy, Diabetic
- Trial name
- PYRAMID (NCT06376240)
- Testing
- Pyridoxamine 300mg per day
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Diabetic Nephropathy
Expression Analysis of Urinary Exosome in Type 2 Diabetic Kidney Disease and Evaluation of Its Clinical Diagnostic Value
Expression analysis of urinary exosome miR-136-5p in type 2 diabetic nephropathy and evaluation of its clinical diagnostic value
- Trial name
- NCT06123871
- Testing
- Grouping based on previous laboratory results, no intervention.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yipeng Liu
Diabetic Nephropathies, Diabetes Mellitus, Type II
Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy
Background The relationship between long-term heavy lead exposure and chronic interstitial nephropathy is well recognized in the previous literatures.
- Trial name
- NCT00237952
- Testing
- EDTA chelating agents
- Where
- 2 sites in China
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Kidney Disease, Diabetic Nephropathy
A Study in Participants With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in participants with kidney disease due to diabetes.
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathy, Diabetic Glomerulosclerosis
- Trial name
- NCT01113801
- Testing
- LY2382770
- Where
- 78 sites in United States, Australia and 5 more
- Volunteers
- 417 people
- Sponsor
- Eli Lilly and Company
Diabetic Kidney Disease
Antiproteinuric Effects of Liraglutide Treatment
The purpose of the study is to determine the effect of Liraglutide on albuminuria in type 2 diabetes.
- Trial name
- LIRALBU (NCT02545738)
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Olmesartan Medoxomil and Diabetic Nephropathy
Evaluation of several olmesartan dosages compared to losartan on proteinuria, renal function and inflammatory markers in patients with diabetic nephropathy
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Proteinuria, Renal Disease
- Trial name
- NCT00362960
- Testing
- Olmesartan medoxomil, Losartan
- Where
- 27 sites in Czechia, Estonia and 5 more
- Volunteers
- 300 people
- Sponsor
- Sankyo Pharma Gmbh
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis
To evaluate the efficacy of fasiglifam 50 mg once daily compared to placebo on glycemic control as measured by glycosilated haemoglobin (HbA1c) over a 16-week treatment period in participants with Type 2 Diabetes Mellitus (T2DM)…
- Trial name
- NCT02015780
- Testing
- Fasiglifam, Antihyperglycemic therapy
- Where
- 30 sites in United States, Bulgaria and 5 more
- Sponsor
- Takeda
Diabetes Type 2, Weight Gain
Effects of Insulin Detemir and NPH Insulin on Renal Handling of Sodium, Fluid Retention, and Weight in Type 2 Diabetic Patients
Hypothesis: Changing type 2 patients treatment from Insulin Insulatard to Insulin Detemir will increase their excretion of sodium in the urine and thereby decrease their extracellular volume and body weight.
- Trial name
- Le-Na (NCT00742976)
- Testing
- Insulin Detemir; Insulin Insulatard, Insulin Detemir, Insulin Insulatard
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes
The pathophysiology of diabetes is multifactorial. Beyond genetic susceptibility loci, a lot of acquired risk factors are involved in the development and progression of the disease.
- Trial name
- LEDA (NCT02895113)
- Testing
- Aspirin
- Where
- Italy
- Volunteers
- 418 people
- Sponsor
- University of Roma La Sapienza
Diabetic Kidney Disease, Cognitive Function
Metabolism of Low Carbohydrate and Ketogenic Diet
This study will assess the preliminary efficacy of a lifestyle intervention including low-carb/ketogenic diet and exercise, enhanced by self-monitoring through health technologies on weight and diabetes outcomes (Glucose, HbA1c)…
- Conditions
- Diabetic Kidney Disease, Cognitive Function, Weight Loss, Diabetic Control
- Trial name
- NCT05071287
- Testing
- mHealth + low-fat diet, mHealth + low-carb/ketogenic diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Type 2 Diabetes Mellitus, DM Nephropathy
Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy
Disease management using a multidisciplinary team to achieve and maintain optimal metabolic and cardiovascular risk factors control in Type 2 diabetic patients with nephropathy reduces the incidence of end stage renal disease…
- Trial name
- NCT00309127
- Testing
- Multidisciplinary team care
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Type 2
The Effects of Lipoic Acid on Glycaemic Control in Type 2 Diabetes
Hypothesis: that lipoic acid supplements taken orally will improve control of blood sugar levels in people with type 2 diabetes.
- Trial name
- NCT00398892
- Testing
- Lipoic acid
- Where
- United Kingdom
- Sponsor
- University of Edinburgh
Heart Failure, Type 2 Diabetes Mellitus
SGLT2 Inhibition in Combination With Diuretics in Heart Failure
The RECEDE-CHF trial is a single centre phase IV, randomised, double-blind, placebo-controlled, crossover trial conducted in NHS Tayside, Scotland comparing empagliflozin 25mg, to placebo in patients with Type 2 Diabetes and mild…
- Trial name
- RECEDE-CHF (NCT03226457)
- Testing
- Empagliflozin 25mg, Frusemide
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- University of Dundee
Diabetic Kidney Disease (DKD), Type 2 Diabetes
A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney Disease
We are conducting this clinical trial to find out whether Guominkang-a traditional Chinese herbal formula-is safe and effective for people with diabetic kidney disease (DKD).
- Conditions
- Diabetic Kidney Disease (DKD), Type 2 Diabetes, Albuminuria
- Trial name
- NCT07907965
- Testing
- Guominkang Granules, Standard Antihypertensive, Antidiabetic, and Lipid-Lowering Regimen
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Beijing University of Chinese Medicine
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy
The purpose of this study is to evaluate the effect of FG-3019 on diabetic kidney disease or diabetic nephropathy.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Diabetic Kidney Disease
- Trial name
- NCT00913393
- Testing
- FG-3019
- Where
- 28 sites in United States
- Volunteers
- 46 people
- Sponsor
- Kyntra Bio