Clinical trials: Type 2 Diabetic Patients
Diabetes Mellitus, Type 2
Post-authorisation Safety Study in Patients With Type 2 Diabetes to Assess the Risk of Liver Injury, Kidney Injury, Urinary Tract and Genital Infections, and Diabetic Ketoacidosis in Patients Treated With Empagliflozin, Compared to DPP-4 Inhibitors
Empagliflozin (Jardiance), a highly potent and selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2), was approved in Europe in May 2014 for the treatment of type 2 diabetes mellitus (T2DM) to improve glycaemic…
- Trial name
- NCT02864914
- Testing
- Empagliflozin, DPP-4 inhibitors
- Where
- United Kingdom
- Volunteers
- 333,580 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
Triglyceride-Glucose Index in Diabetic Nephropathy in Type 2diaberes Mellitus Patients
The aim of the present study is to investigate the associations between the TyG index and diabetic nephropathy in patients with type2 DM .
- Trial name
- NCT05602532
- Volunteers
- 100 people
- Sponsor
- Assiut University
Type2 Diabetes
Identification and Validation of Noninvasive Biomarkers of the Diagnosis and Severity of NASH in Type 2 Diabetics
Metabolic diseases of the liver are silent affections whose morbidity is important. About 70% of patients with type 2 diabetes (T2D) are concerned.
- Trial name
- Quid-Nash (NCT03634098)
- Testing
- new quantitative imaging techniques with contast products, blood sample, second generation tests
- Where
- France
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes
Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone
The purpose of this study is to assess the safety and effectiveness of KRP-104 on glycemic control in patients with type 2 diabetes inadequately controlled on metformin alone.
- Trial name
- Synergy104 (NCT00995345)
- Testing
- KRP-104
- Where
- 45 sites in United States, Argentina and 5 more
- Volunteers
- 403 people
- Sponsor
- ActivX Biosciences, Inc.
Type 2 Diabetes
Improving Adherence and Commitment to Treatment in Diabetic Patients
In the IMPACT project, the investigators want to improve adherence and commitment to treatment.
- Trial name
- NCT02530840
- Testing
- medical team, peers group, SMS notification
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Clalit Health Services
Diabetes Mellitus, Type 2
Closed Loop Glucose Control in Patients With Type 2 Diabetes
This is a proof of concept safety study of an artificial intelligence based closed loop glucose control system designed for use in the intensive care unit setting.
- Trial name
- NCT05386849
- Testing
- FUSION closed loop glucose control system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ideal Medical Technologies
STEMI, No-Reflow Phenomenon
Insulin Resistance and Its Association With no Reflow Phenomenon After Primary PCI in Type II Diabetic STEMI Patients.
To investigate the relationship between the TyG index, coronary lesion complexity assessed by the SYNTAX score, and the development of the no-reflow phenomenon in STEMI patients with T2DM.
- Conditions
- STEMI, No-Reflow Phenomenon, Diabetic Patient
- Trial name
- NCT07706335
- Testing
- PCI
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetic Patient (Type 1,2, MODY, Secondary) or With Corticosteroid-induced Diabetes Following Initiation of Corticosteroid Treatment
Tele-expertise in Patients With Diabetes Hospitalized for Covid-19 Infection
Diabetes is a major factor of morbi-mortality in Covid-19 infection. Currently, steroid therapy is required in patients under oxygen therapy. This treatment is associated with hyper glycaemia in patients with diabetes.
- Trial name
- COVIDEX (NCT04726163)
- Testing
- Continuous blind glucose measurement device (Free style Pro)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetes (DM), Diabetic Ketoacidosis
Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes
Diabetic ketoacidosis (DKA) is increasingly recognized in adults with "ketone-prone" type 2 diabetes. In many of these patients, the pancreas can still make insulin but becomes temporarily "stunned" during severe, prolonged high…
- Conditions
- Diabetes (DM), Diabetic Ketoacidosis, Ketosis Prone Diabetes, Hyperglycaemia (Diabetic)
- Trial name
- NCT07167693
- Testing
- Arginine hydrochloride, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- David K Carroll
Diabetes Mellitus, Type 2
Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED)
The purpose of this study is to determine if the addition of ezetimibe 10 mg daily to ongoing 20 mg simvastatin daily will reduce LDL Cholesterol to a greater extent than increasing the dose of simvastatin to 40 mg daily in Type…
- Trial name
- NCT00551876
- Testing
- MK0653, ezetimibe / Duration of Treatment: 30 Weeks, Comparator : ezetimibe (+) simvastatin / Duration of Treatment: 30 Weeks
- Volunteers
- 214 people
- Sponsor
- Organon and Co
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Taiwan
This study is conducted in Asia. The aim of this observational study is to evaluate the current status of diabetes management, control, and complications in diabetic subjects in Asia.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare Asia (NCT00887874)
- Testing
- No treatment given
- Where
- Taiwan
- Volunteers
- 2,370 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2, Cardiovascular Diseases
The Cardio-Metabolic Clinic
This study aims to investigate whether a Cardio-Metabolic Clinic can protect the cardiovascular health of patients with both diabetes and cardiovascular disease.
- Trial name
- ProtecT-2-D (NCT06203860)
- Testing
- Cardio-Metabolic Clinic
- Where
- Denmark
- Volunteers
- 1,600 people
- Sponsor
- Odense University Hospital
Diabetic Patients Type 1 and 2, Podologic Grade From 0 to 3
Transient Thermal Behavior and Diabetic Foot
In our study, the investigators propose to analyze the transient thermal responses taken at the level of the sole of the foot, following the application of a cold stimulus.
- Trial name
- PICOTE (NCT03872089)
- Testing
- Infrared Thermography
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus
Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus
This is a safety and dose finding efficacy study to evaluate the effects of BGP-15 over the dose range of 100 mg/day to 400 mg/day.
- Trial name
- NCT01069965
- Testing
- BGP-15 100 mg QD, BGP-15 100 mg BID, BGP-15 200 mg QD
- Where
- 30 sites in United States, Germany and 1 more
- Volunteers
- 196 people
- Sponsor
- N-Gene Research Laboratories, Inc.
Diabetes Mellitus, Type 2
BI 1356 (Linagliptin) in Combination With Metformin and a Sulphonylurea in Type 2 Diabetes
The objective of the current study is to investigate the efficacy, safety and tolerability of BI 1356 (5 mg once daily) compared to placebo given for 24 weeks as add-on therapy to metformin in combination with a sulphonylurea in…
- Trial name
- NCT00602472
- Testing
- linagliptin
- Where
- 100 sites in Argentina, Belgium and 9 more
- Volunteers
- 1,058 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
New Patient Support Program in Type 2 Diabetes
Non-profit observational study on the role of the community pharmacist and the "pharmacy of services" in the case management of the diabetic patient
- Trial name
- NCT03752567
- Testing
- Follow up
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Farmacia La Regina s.r.l.
Osteoarthritis
GLP1 Analogues and the Risk of Osteoarthritis
Assessing the effects of GLP1 RA Vs SGLT2 Inhibitors vs. Standard of care in joint pain, physical function, stiffness, and improving Quality of Life for patients with type 2 diabetes.
- Trial name
- NCT07360457
- Testing
- GLP-1 analog, SGLT2 inhibitor, Antidiabetic
- Volunteers
- 390 people
- Sponsor
- Beni-Suef University
Diabetes, Diabetes Mellitus, Type 2
An Observational Study in Type 2 Diabetic Patients on Oral Antidiabetic Drugs and Basal Insulin in Near East Countries
This study is conducted in Asia. The aim of this observational study is to investigate the safety and efficacy of insulin detemir as add-on therapy in type 2 diabetic patients who are using oral antidiabetic drugs.
- Trial name
- BO2NE (NCT00842192)
- Testing
- insulin detemir
- Where
- 4 sites in Israel, Jordan and 2 more
- Volunteers
- 2,155 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Empagliflozin in Chinese Female and Male Patients With Type 2 Diabetes Mellitus
the pharmacokinetics, pharmacodynamics and safety and tolerability of single and multiple oral doses of BI 10773 at low dose once daily (q.d.) and high dose q.d.
- Trial name
- NCT01316341
- Testing
- BI10773
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Boehringer Ingelheim
Diabetes, Stress
Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus
General anesthesia can be considered as a combination of hypnosis, antinociception and immobility. Explore the effect of three kinds of anesthesia,that is the total intravenous anesthesia, inhalation anesthesia and inhalation and…
- Conditions
- Diabetes, Stress, Anesthesia
- Trial name
- NCT01963546
- Testing
- different types of anesthesia, Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command