Clinical trials: Type 2 Diabetic Patients
DKA
Early Administration of Insulin Glargine in Patients With Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a medical emergency that is associated with significant morbidity and mortality for both patients with type I and type II diabetes.
- Trial name
- NCT06007508
- Testing
- Insulin Glargine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- HealthPartners Institute
Type 2 Diabetes
Basal Insulin for Type 2 Diabetes Patients Treated in Outpatient Clalit Clinics
Treatment of diabetes mellitus type II with basal insulin, for patients treated in Clalit outpatient clinics that are not adequately controlled with current treatment.
- Trial name
- Lapas II (NCT00726674)
- Where
- Israel
- Volunteers
- 1,229 people
- Sponsor
- Sanofi
Diabetic Nephropathy
"Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes"
Chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) is a major cause of morbidity, commonly associated with persistent albuminuria and progressive renal decline.
- Trial name
- NCT07598864
- Testing
- Dapagliflozin +Finerenone arm, Dapagliflozin arm
- Where
- Bangladesh
- Volunteers
- 88 people
- Sponsor
- Chittagong Medical College
Diabetes Mellitus Type 2
A Clinical Trial Assessing The Impact Of Inhaled Insulin On Glucose Control In Patients With Type 2 Diabetes Mellitus
To assess the impact on glucose control by inhaled insulin in patients with type 2 diabetes who are not well controlled on 2 or more oral anti-diabetic agents
- Trial name
- NCT00282971
- Testing
- Inhaled Insulin (Exubera), Standard of Care
- Where
- 64 sites in Canada, France and 5 more
- Volunteers
- 354 people
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
Surgical Treatment of Non-obese Type 2 Diabetic Patients With Duodenal Exclusion
Diabetes reversion is observed after bariatric surgeries even before significant weight loss could explain it, mainly in predominantly malabsorptive procedures (98,9% for biliopancreatic diversion or duodenal switch), followed by…
- Trial name
- NCT00566358
- Testing
- Duodenal exclusion surgery
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- University of Campinas, Brazil
Obesity, Type 2 Diabetes Mellitus
Surgical Treatment in Diabetic Patients With Grade 1 Obesity
There will be a randomized clinical trial, non-blind, 3-arm treatment (medical, surgical, gastric bypass and ileal transposition surgery with and sleeve), which will be conducted in a single center - S.B.S.
- Trial name
- NCT01857076
- Testing
- Gastric bypass surgery, Surgical ileal transposition with sleeve, Clinical
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Hospital Sirio-Libanes
Controlled Type 2 Diabetic Patients With Periodontitis
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
The present randomized placebo-controlled trial aims to evaluate and compare the clinical and radiographic efficacy of subgingivally delivered 0.05% zoledronate gel and 1% metformin gel as adjuncts to minimally invasive…
- Trial name
- NCT07753317
- Testing
- All participants will receive MINST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Diabetic Neuropathies
A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain
The objective of this study is to investigate the safety and efficacy of an investigational drug, V3381, for the treatment of diabetic peripheral neuropathic (DPN) pain (pain in one's feet and legs, or even in one's hands and…
- Trial name
- NCT00375960
- Testing
- V3381
- Where
- 6 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Vernalis (R&D) Ltd
Diabetes Mellitus, Type 2
Pharmacokinetics and Pharmacodynamics Trial With Linagliptin (BI 1356) 5mg in African American Type 2 Diabetic Patients
The objective of this trial is to investigate the pharmacokinetics and pharmacodynamics of linagliptin (BI 1356) 5 mg administered orally in patients with Type 2 diabetes mellitus of African American origin.
- Trial name
- NCT00935220
- Testing
- linagliptin QD (once daily) for 7 days
- Where
- 6 sites in United States
- Volunteers
- 41 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
Effects of Artificial Sweeteners on Glucose Metabolism in Patients With Type 2 Diabetes
To investigate the effects of artificial sweeteners on glucose metabolism in newly diagnosed type 2 diabetic patients
- Trial name
- SWEETS (NCT04185662)
- Testing
- sucralose
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Diabetic Macular Edema, Type 1 Diabetes Mellitus
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease
The primary objective of the study is to determine if treatment with high-dose aflibercept (HD) at intervals of 12 or 16 weeks provides non-inferior best corrected visual acuity (BCVA) compared to aflibercept dosed every 8 weeks.
- Conditions
- Diabetic Macular Edema, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
- Trial name
- PHOTON (NCT04429503)
- Testing
- aflibercept, High-dose aflibercept
- Where
- 138 sites in United States, Canada and 6 more
- Volunteers
- 660 people
- Sponsor
- Regeneron Pharmaceuticals
Diabetes Mellitus, Type 2
Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020)
The purpose of the study is to assess how MK0767, compared to Metformin, performs in lowering blood glucose levels in patients whose Type II diabetes is not controlled by diet and exercise.
- Trial name
- NCT00543361
- Testing
- MK0767, Comparator: metformin
- Volunteers
- 382 people
- Sponsor
- Merck Sharp & Dohme LLC
Type II Diabetes
Educational Intervention Targeting Statin Therapy and Compliance in Diabetic Patients
The objective of the study is to measure changes in compliance to statin therapy in patients with type 2 diabetes after an educational intervention.
- Trial name
- STADIA (NCT04499846)
- Testing
- Therapeutic education
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Lille Catholic University
Diabetes Mellitus, Type 2, Pre Diabetes
Relationship Between HbA1c Level, Sleep Quality and Sleep Duration
The study will be conducted during the period of, January 2019 - August 2019 with pre-diabetic participants on a NHS England funded National Diabetes Prevention Program (NDPP) with a clinically diagnosed Haemoglobin A1c (HbA1c)…
- Conditions
- Diabetes Mellitus, Type 2, Pre Diabetes, Sleep Disorder
- Trial name
- NCT04032561
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Hertfordshire
Diabetes Mellitus, Type 2
Improving the Care of Diabetic Patients: A Randomized Trial of a Family Physician Office-Based Chronic Disease Care Model for Patients With Type 2 Diabetes
The purpose of the study is to determine the efficacy of a family physician practice-based model of chronic disease management (CDM) based in Primary Care Networks (PCN's) that is integrated with the Capital Health Regional…
- Trial name
- NCT00789282
- Testing
- multidisciplinary approach, multifactorial approach - for enhanced care group, reflects current patterns of care
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Alberta
Type 2 Diabetes
Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients
The aim of this study is to evaluate the effect of vildagliptin on copeptin in comparison to glimepiride, and whether copeptin could be used as a marker for the efficacy of vildagliptin in type 2 diabetes mellitus patients, and…
- Trial name
- NCT06068686
- Testing
- Vildagliptin 50 MG, Glimepiride 3 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Damanhour University
Obesity, Diabetes Mellitus, Type 2
Effect of BAriatric Surgery Versus Optimal Medical Therapy on Cardiovascular Health and Atherosclerosis in Obese, Type II Diabetic Patients
To assess the impact of weight loss due to bariatric surgery, as compared to the effect of optimal medical therapy alone on endothelial function, subclinical atherosclerosis, cardiovascular autonomic function in obese patient…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Atherosclerosis
- Trial name
- BASTA (NCT02331420)
- Testing
- Gastric bypass, Medical therapy
- Volunteers
- 58 people
- Sponsor
- Catholic University of the Sacred Heart
Type 2 Diabetes Mellitus
JanUmet Before Insulin Lantus In Eastern Population Evaluation Program (JUBILEE) In Type 2 Diabetic Patients
To evaluate the efficacy and safety of a new treatment regimen of metformin plus sitagliptin (Janumet) followed by a long-acting basal insulin (Lantus) treatment compared to the usual treatment regimen of metformin followed by…
- Trial name
- JUBILEE (NCT01269996)
- Testing
- Janumet, Lantus, metformin, gliclazide, protaphane
- Where
- Hong Kong
- Volunteers
- 71 people
- Sponsor
- Chinese University of Hong Kong
Obesity
A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients
The purpose of this study is to determine if CP-945,598 is effective in the treatment of obesity in type 2 diabetic patients.
- Trial name
- NCT00391196
- Testing
- CP-945,598, CP-945,598 Treatment B
- Where
- 91 sites in United States, Argentina and 9 more
- Volunteers
- 975 people
- Sponsor
- Pfizer
Type 2 Diabetes
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
The overarching hypothesis of this study is that vildagliptin (vilda) as add on therapy to metformin (met) in Egyptian type 2 diabetic obese patient will produce an equal, if not better, glycemic control and will reduce…
- Trial name
- NCT07077525
- Testing
- Dapagliflozin + Metformin, Vildagliptin + Metformin
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Al-Azhar University