Clinical trials: Type 2 Respiratory Failure
Acute Hypercapnic Respiratory Failure
High Pressure Non Invasive Ventilation in Hypercapnic Respiratory Failure
High pressure NIV is a pressure limited ventilation, stating IPAP pressure at 20 cmH2O and gradually increasing pressure up to 30 cmH2O according to patient tolerance.
- Trial name
- NCT04362787
- Testing
- High pressure non invasive ventilation in acute hypercapnic respiratory failure
- Volunteers
- 52 people
- Sponsor
- Assiut University
Respiratory Failure With Hypercapnia
Listen to a Audio Book
This study investigates how listening to audiobooks affects agitation scores and respiratory parameters (like breathing rate, depth, and oxygen saturation) in patients receiving non-invasive mechanical ventilation (NIMV) for…
- Trial name
- NCT06944093
- Testing
- audio book
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Multiple Myeloma
A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg
1. Planned enrollment period One year (The planned number of patients to be enrolled is set to 400 patients.) Since all patients who are prescribed with Pomalyst are registered in RevMate®, enrollment using the Registration Form…
- Trial name
- NCT02921828
- Where
- 2 sites in United States, Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Obesity Hypoventilation Syndrome (OHS)
HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS
1. Assessment of benefits of HVNI in management of obesity hypoventilation syndrome complicated with acute hypercapnic respiratory failure. 2.
- Trial name
- NCT05805293
- Testing
- High-Velocity Nasal Insufflation Therapy, Non-Invasive Ventilation
- Volunteers
- 56 people
- Sponsor
- Assiut University
Pressure Ulcer, Noninvasive Positive Pressure Ventilation
The ROTAtional-USE of Interface STUDY
In this trial investigators will explore if a protocolized rotational use of interfaces i.e., masks, during noninvasive positive pressure ventilation (NPPV) compared to standard care is clinically effective and cost-effective in…
- Conditions
- Pressure Ulcer, Noninvasive Positive Pressure Ventilation, Acute Hypercapnic Respiratory Failure
- Trial name
- ROTA-USE (NCT05513508)
- Testing
- Protocolized rotational use of interfaces, Standard of care
- Where
- Italy
- Volunteers
- 478 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Chronic Respiratory Failure, Acute Respiratory Failure
Automated Oxygen Titration With the EMILY.AI Device in a Respiratory Intermediate Care Unit
This study evaluates EMILY.AI, an investigational (non-CE-marked) smart oxygen valve that automatically adjusts the oxygen flow delivered to a patient, second by second, according to oxygen saturation (SpO2), heart rate and…
- Conditions
- Chronic Respiratory Failure, Acute Respiratory Failure, Hypoxemic Respiratory Failure, Hypercapnic Respiratory Failure
- Trial name
- NCT06952816
- Testing
- Emily.AI, Manual oxygen titration
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Aether Tech S.L.
Ventilatory Failure
Non-invasive Ventilator Modems: a Qualitative Study
Advances in technology has meant that domiciliary non-invasive (NIV) devices can be remotely monitored via modems in patients' homes. Possible benefits and challenges of modem technology have yet to be established.
- Trial name
- NCT03905382
- Testing
- Qualitative
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Acute on Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome (OHS)
"Post-acute Pickwick Study" (Postacute-Pick-2020)
We propose to carry out a large multicentric, multinational, randomized controlled trial with two phases (two sequential randomized controled trials) to answer two questions: 1) Should hospitalized patients with recently…
- Trial name
- NCT04317326
- Testing
- "Lifestyle modifications" group (Control), Automatic NIV, CPAP treatment group
- Sponsor
- Juan F. Masa
Acute Respiratory Failure, Hypercapnic Respiratory Failure
Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation
This study compares a volume targeted pressure support non-invasive ventilation with an automatic PEP regulation (AVAPS-AE mode) to a pressure support non-invasive ventilation (S/T mode) in patients with acute hypercapnic…
- Conditions
- Acute Respiratory Failure, Hypercapnic Respiratory Failure, Respiratory Acidosis, Obesity
- Trial name
- VONIVOO (NCT04131660)
- Testing
- AVAPS-AE mode during NIV, S/T mode during NIV
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Rouen
Type II Respiratory Failure, Hypercapnic Respiratory Failure
Post-Extubation High-Flow Nasal Cannula Versus Non-Invasive Ventilation in Type II Respiratory Failure
Acute hypercapnic respiratory failure is characterized by elevated arterial carbon dioxide levels and commonly occurs in patients with chronic respiratory diseases.
- Trial name
- NCT06918288
- Testing
- High-Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
COPD, Chronic Hypercapnic Respiratory Failure
Intelligent Volume Assured Pressure Support to Improve Sleep Quality and Respiratory Events in Patients With Non Invasive Ventilation
Aim of this prospective randomized trial is to compare non invasive ventilation (NIV) with pressure control (BiPAP-ST) to volume assured pressure support (iVAPS) with regards to sleep quality and alveolar ventilation in patients…
- Trial name
- NCT01986413
- Testing
- pressure controlled ventilation BIPAP ST, volume assured pressure support IVAPS, NIV
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV