Clinical trials: Type I Diabetes Mellitus
Type 1 Diabetes Mellitus, Diabetes Self-Management
Health Promotion Model-Based Education and Motivational Interviewing for Parents of Children With Type 1 Diabetes
This quasi-experimental study will aim to evaluate the effects of Health Promotion Model-based education and motivational interviewing on diabetes self-management and quality of life among parents of children diagnosed with type…
- Conditions
- Type 1 Diabetes Mellitus, Diabetes Self-Management, Quality of Life, Health Promotion Model (HPM)
- Trial name
- HPM-T1D-MI (NCT07212218)
- Testing
- Health Promotion Model-Based Education and Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Saglik Bilimleri Universitesi
Type 1 Diabetes, Type 2 Diabetes
Understanding and Optimizing Care for Young Adults With Type 1 and Type 2 Diabetes Mellitus Transitioning to Adult Care
In this study, we will determine the feasibility of an innovative care model for young adults with diabetes and compare the primary and secondary outcomes in the innovative model to those in the usual care model for adult…
- Trial name
- NCT05229718
- Testing
- Diabetes Collaborative Care Model for Young Adults, Usual Care Model
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts General Hospital
Diabetic Neuropathies
Eye-tracking-based Artificial Intelligence Detects Abnormalities of the Oculomotor System in Type 1 Diabetes
Abnormalities of the oculomotor system may represent an early sign of diabetic neuropathy and are currently poorly studied. The investigators designed an eye-tracking-based test to evaluate the oculomotor function in patients…
- Trial name
- EyekonT1D (NCT04608890)
- Testing
- Eye-tracking video test
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Diagnosis and Physiopathology of Insulin Allergy
Insulin allergy (IA) is still observed even with recombinant human insulin and insulin analogs. Obviously, the usual attitude facing an allergy, i. e.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hypersensitivity, Immediate Hypersensitivity
- Trial name
- Allerdiab (NCT01407640)
- Testing
- Allergy tests
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Taiwan
This study is conducted in Asia. The aim of this observational study is to evaluate the current status of diabetes management, control, and complications in diabetic subjects in Asia.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare Asia (NCT00887874)
- Testing
- No treatment given
- Where
- Taiwan
- Volunteers
- 2,370 people
- Sponsor
- Novo Nordisk A/S
Cutaneous Melanoma
Expression of IL4 Induced Gene 1 in Patients With Cutaneous Melanoma: Value in Prognosis and/or in Predictive Response to Immune Checkpoint Inhibitors
To characterize and quantify immune cells expressing the Interleukine 4 induced gene 1 (IL4I1) immunosuppressive enzyme in the blood and in tissue of melanoma patients (primary tumor, sentinel lymph nodes and cutaneous…
- Trial name
- ENZYMELA (NCT04253080)
- Testing
- Blood sample, Cutaneous melanoma biopsy
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus
A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd also known as retogatein compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous…
- Trial name
- DIAGNODE-3 (NCT05018585)
- Testing
- Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Colecalciferol 2000 IU
- Where
- 60 sites in United States, Czechia and 7 more
- Volunteers
- 321 people
- Sponsor
- Diamyd Medical AB
Eating Disorders, Type 1 Diabetes
Eating Disorder Prevention Program for Women With T1D
This study aims to test the effectiveness of an evidence-based eating- disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05264376
- Testing
- Diabetes Body Project, Educational Control
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
A Single-Blind, Placebo-Controlled, Dose-Ranging Trial of Oral HDV-Insulin in Patients With Type 2 Diabetes Mellitus
A study designed to determine the appropriate doses of Oral HDV Insulin at meal times.
- Trial name
- NCT00521378
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Diasome Pharmaceuticals
Diabetes, Diabetes Mellitus, Type 1
Comparison of Insulin Detemir Plus Insulin Aspart With Insulin NPH Plus Human Soluble Insulin in Subjects With Type 1 Diabetes
This trial is conducted in Europe and South America. The aim of this trial is to compare the glycaemic control of insulin detemir plus insulin aspart with that of insulin NPH plus human soluble insulin in subjects with type 1…
- Trial name
- NCT01486940
- Testing
- insulin detemir, insulin aspart, insulin NPH
- Where
- 75 sites in Argentina, Croatia and 13 more
- Volunteers
- 598 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes Mellitus
Dapagliflozin Evaluation in Patients With Inadequately Controlled Type 1 Diabetes
The purpose of this study is to determine if adding dapagliflozin to insulin is a safe and effective therapy to improve glycemic control in patients with type 1 diabetes.
- Trial name
- DEPICT 2 (NCT02460978)
- Testing
- Dapagliflozin
- Where
- 136 sites in United States, Argentina and 11 more
- Volunteers
- 815 people
- Sponsor
- AstraZeneca
Type I Diabetes
Monitoring of Nocturnal Hypoglycemia Using EarlySense Monitoring Device
This study observes the continuous measurement of breathing patterns, heart rate, restlessness, and tremor in sleep using the EarlySense ES 16 device as a tool in the management of hypoglycemia in pediatric type I diabetes…
- Trial name
- NCT00361608
- Testing
- EarlySense ES 16
- Where
- Israel
- Sponsor
- EarlySense Ltd.
Type 1 Diabetes
A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes
This study aims to compare inpatient glycemic control by measuring the percentage of time in the range of 70-180 mg/dl and the frequency of hypoglycemia between Dexcom G7 Continuous Glucose Monitoring (CGM) and Point of Care…
- Trial name
- NCT06752928
- Testing
- Dexcom G7 rtCGM, Capillary Blood glucose Testing (POC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Telemedicine Continuous Remote Monitoring of Adults With Uncontrolled Diabetes Mellitus
The purpose of this single center observational study is to determine the effect of continuous remote continuous glucose monitor (CGM) reporting coupled with a telemedicine intervention (Tele-CGM program) on levels of HbA1C in…
- Trial name
- TELEMTRRDM (NCT05161793)
- Testing
- Tele-Monitor DM
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of Southern California
Diabetes Mellitus, Insulin-Dependent
Randomized Clinical Trial to Assess the Effectiveness of the GlucoWatch Biographer
This study will evaluate the safety and effectiveness of a continuous glucose monitor in children with Type 1 diabetes mellitus (T1DM).
- Trial name
- NCT00069628
- Testing
- GlucoWatch® G2™ Biographer (GW2B), Continuous Glucose Monitoring System (CGMS)
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research
Diabetes Mellitus, Type 1
DBLG1 System With TERUMO MEDISAFE WITH Insulin Pump Trial
This study conducted in 90 adults living with type 1 diabetes is an interventional single-arm open-label before/after multicentric national study conducted as a clinical investigation according to the law EU 2017/745 art. 62.
- Trial name
- BETTER (NCT05628532)
- Testing
- Use of the DBLG1 system
- Where
- 10 sites in France
- Volunteers
- 90 people
- Sponsor
- Diabeloop
Type 1 Diabetes, Exercise
Exercise-induced Glycemic Variations and Hybrid Closed-loop Systems
Type 1 diabetes is characterized by high risk of hypoglycemia and associated fear of hypoglycemia. Hypoglycemia risk is higher during and after physical activity, especially aerobic activity of long duration.
- Trial name
- SAFE-T1D (NCT05736263)
- Testing
- Moderate intensity exercise, High intensity interval exercise, Combined exercise
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Type 1 Diabetes Mellitus
Phipps Conservatory's 5210 Let's Move Pittsburgh and Impact on Youth With T1D
Managing T1D requires a demanding regimen to keep blood sugars in control and stay healthy. Despite recent advances, this remains extremely challenging for children and their families, who usually report having the most…
- Trial name
- NCT07780487
- Testing
- Virtual cooking classes, Routine Diabetes Care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Pittsburgh
Type 1 Diabetes
Closing the Loop in Adolescents During Non-compliance Behaviours
The ultimate goal of the investigators ongoing research is the development of a closed-loop system for insulin delivery, which can help people with type 1 diabetes (T1D) attain a tight glucose control avoiding the risk of…
- Trial name
- NCT01629277
- Testing
- Closed-loop, standard insulin pump
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Cambridge
Type 1 Diabetes Mellitus
Reducing the Risk of Metabolic Decompensation in Diabetic Adolescents by Supervised School Administration of Insulin
This is a pilot study to examine and compare the efficacy of supervised injections of long acting insulins degludec and glargine to protect youth with poorly controlled type 1 diabetes (T1D) from development of ketones.
- Trial name
- NCT03400501
- Testing
- Insulin Degludec, Insulin Glargine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Yale University
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