Clinical trials: Type II Diabetes Mellitus
Type 2 Diabetes
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
The objective of this study is to evaluate the efficacy and safety of teneligliptin 20 mg orally administered once daily for 24 weeks compared with placebo in patients with type 2 diabetes mellitus who have inadequate glycemic…
- Trial name
- TERA 305 (NCT05504226)
- Testing
- Teneligliptin (as Teneligliptin Hydrobromide) 20 Mg Oral Tablet
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Handok Inc.
Diabetes Mellitus, Type 2
A Clinical Study to Assess the Safety, Tolerability, and Activity of Oral SRT2104 Capsules Administered for 28 Days to Subjects With Type 2 Diabetes Mellitus
Randomized, placebo-controlled, parallel-group, double-blind, multiple-dose, activity and safety clinical study of SRT2104 administered orally once daily for 28 consecutive days.
- Trial name
- NCT01018017
- Testing
- SRT2104
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes Mellitus, Health Behavior
The Together on Diabetes Intervention - a Realist Evaluation
The Danish healthcare system is universal and free of charge for Danish citizens, as all healthcare services are financed by general taxes.
- Conditions
- Type 2 Diabetes Mellitus, Health Behavior, Delivery of Health Care
- Trial name
- NCT04722289
- Testing
- Together on Diabetes
- Volunteers
- 20 people
- Sponsor
- Center for Diabetes, Copenhagen Municipality
Type 2 Diabetes
A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus
The purpose of this clinical research study is to learn if BMS-512148 is effective in controlling blood sugar levels as determined by HbA1c and fasting plasma glucose in patients who have been diagnosed with Type 2 diabetes.
- Trial name
- NCT00263276
- Testing
- dapagliflozin, metformin
- Where
- 144 sites in United States, Canada and 2 more
- Volunteers
- 389 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2
Pilot Trial of the Nutrition-Supported Diabetes Education Program
This is a pragmatic, pilot randomized controlled trial (RCT) of the Nutrition-Supported Diabetes Education Program (NU-DSMP). This study will test the feasibility and preliminary impact of providing diabetes-tailored food support…
- Trial name
- NU-DSMP (NCT05067452)
- Testing
- Food support, Case-management
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2
A Multi-center 12-week Study of HMS5552 in T2DM
This study evaluates the safety, tolerability, efficacy and population PK of HMS5552 in type 2 diabetic adult subjects,there will be 5 groups ,4 groups will receive HMS5552,while 1 will receive placebo.
- Trial name
- NCT02561338
- Testing
- HMS5552
- Where
- China
- Volunteers
- 258 people
- Sponsor
- Hua Medicine Limited
Type 2 Diabetes
18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)
Saxagliptin is a new investigational medication being developed for treatment of type 2 diabetes. This study is designed to assess the efficacy and tolerability of saxagliptin in addition to metformin and compare to sitagliptin…
- Trial name
- NCT00666458
- Testing
- saxagliptin, sitagliptin
- Where
- 87 sites in Argentina, Belgium and 7 more
- Volunteers
- 822 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Non-Insulin-Dependent, Dyslipidemia
Safety Study of BMS-816336 in Healthy Male Subjects
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics following single oral doses of BMS-816336 in healthy male subjects.
- Trial name
- NCT00979368
- Testing
- BMS-816336
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Type 2 Diabetes Patients
A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients
PF-04620110 is a novel compound proposed for the treatment of Type 2 diabetes mellitus. The primary purpose of this trial is to evaluate the safety and tolerability, and pharmacodynamics, of multiple oral doses of PF-04620110 in…
- Trial name
- NCT01298518
- Testing
- PF-04620110
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Pfizer
Type 2 Diabetes
LINK-IT: Leveraging vIdeos and commuNity Health worKers to Improve Diabetes OuTcomes
The overall goal of this study is to examine the efficacy of the video-based Diabetes Self-Management Education and Support (DSMES) (hereafter VIDEO), or the video-based DSMES+community health worker (CHW) intervention (hereafter…
- Trial name
- LINK-IT (NCT06319716)
- Testing
- Video-Based Diabetes Self-Management Education and Support (DSMES), Community Health Worker (CHW) Support
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes Mellitus
A Study to Test MK-0941 in Adults With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0941-018)
The purpose of this study is to test the effect MK-0941 as add-on therapy for adults taking insulin for Type 2 Diabetes.
- Trial name
- NCT00824616
- Testing
- MK-0941, Insulin
- Volunteers
- 68 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes Mellitus
Effects of Low- or High-glycemic Index Diets on Metabolic and Inflammatory Responses in Diabetics
Background/Aims: Verify the effects of glycemic index (GI) on body composition, and on inflammatory and metabolic markers concentrations.
- Trial name
- NCT02383784
- Testing
- Low GI index diet, High GI diet
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of Vicosa
Diabetes Mellitus, Type 2
Dining With Diabetes in Pennsylvania
Penn State Extension's Dining with Diabetes program is an evidence-based community education program for people with or at risk for type 2 diabetes.
- Trial name
- DWD (NCT04080960)
- Testing
- Lifestyle modification education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Penn State University
Diabetes Mellitus, Type 2, Insulin Resistance
Production of Free Fatty Acids From Blood Triglycerides
The overall hypothesis of these studies is that circulating triglycerides, coming primarily from fat in the diet, are an important source of free fatty acids.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Dyslipidemias
- Trial name
- NCT00911482
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mitochondria, Metformin
Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy
he goal of this clinical trial is to compare the mitochondrial redox effects of imeglimin versus metformin monotherapy in adults with newly diagnosed Type 2 diabetes mellitus who are treatment-naive.
- Trial name
- MIRROR-DM (NCT07436182)
- Testing
- Imeglimin, Metformin 1000 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Mansoura University
Type 2 Diabetes
Study on the Feasibility of Community Doctors Guided by Specialists to Use Basic Insulin
At present, one of the reasons for the low blood sugar control rate in China is related to the late use of basic insulin and insufficient dose adjustment.
- Trial name
- NCT04553380
- Testing
- basic insulin
- Volunteers
- 150 people
- Sponsor
- Shenzhen Second People's Hospital
Diabetes Mellitus Type 2, Infection
Automated Insulin Delivery Versus Daily Injections for Hospital Diabetes Care
Aim The investigators aim to investigate if automated insulin delivery systems (AID) improve in-hospital glycemic and clinical outcomes in patients with type 2 diabetes compared to standard-of-care with a pen-basal-bolus insulin…
- Conditions
- Diabetes Mellitus Type 2, Infection, CGM
- Trial name
- NCT07645079
- Testing
- automated insulin delivery system, GlucoTab, Control-arm
- Where
- 2 sites in Austria, Denmark
- Volunteers
- 92 people
- Sponsor
- Steno Diabetes Center Copenhagen
Pre-diabetes
Therapeutic Innovation in Type 2 DIABetes (IT-DIAB)
The main objective of the study is to follow prospectively a cohort of patients with pre-diabetes to understand the pathophysiological mechanisms involved in switching from pre-diabetes to type 2 diabetes and to identify new…
- Trial name
- IT-DIAB (NCT01218061)
- Testing
- Pre-diabetes screening
- Where
- France
- Volunteers
- 366 people
- Sponsor
- Nantes University Hospital
Diabetes Mellitus, Gastroparesis
Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People
The purpose of this study is to determine the effects of the drug lixisenatide on blood sugar levels, stomach emptying, blood pressure and heart rate, release of gut hormones and blood flow in the gut after a glucose drink in…
- Trial name
- Lixi (NCT02308254)
- Testing
- Lixisenatide
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Catecholamine; Overproduction, Catecholamine; Secretion
Sympathetic Activity and Cardiometabolic Complications
Recent studies on catecholamine physiology have shown a direct correlation with arterial hypertension, overcoming the exclusive role in the diagnosis and follow-up of chromaffin tumors.
- Conditions
- Catecholamine; Overproduction, Catecholamine; Secretion, Metabolic Syndrome, Hypertensive Heart Disease
- Trial name
- SYMPACT (NCT04495231)
- Where
- Italy
- Volunteers
- 1,380 people
- Sponsor
- University of Turin, Italy