Clinical trials: Type II Diabetes Mellitus
Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
ED Diabetes Screening and Outpatient Care - Aim 3
This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate…
- Trial name
- NCT05899023
- Testing
- Telehealth Bridge Visits, Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Cardiovascular Diseases, Heart Diseases
Lifestyle Modification Program to Reduce Risk of Coronary Heart Disease in Latina Women With Diabetes
The Viva Bien! trial will comprehensively evaluate a multiple risk factor intervention (diet, physical activity, stress management, social support, and smoking cessation) in a randomized effectiveness trial, which will be offered…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT00233259
- Testing
- Mediterranean Diet, Physical Activity, Stress Management
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Oregon Research Institute
Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)
The purpose of the study is to compare how sitagliptin and glipizide lower blood glucose levels in participants with moderate or severe renal insufficiency.
- Trial name
- NCT00509262
- Testing
- Sitagliptin, Glipizide
- Volunteers
- 426 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2, Hypertension
Arterial Ablation for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities
This study is assess the safety and performance of the Neurotronic Infusion catheter for treatment of patients with Type 2 Diabetes (T2DM) and hypertension.
- Trial name
- NECTAR III (NCT05363761)
- Testing
- Neurotronic Infusion Catheter
- Where
- 3 sites in Panama, Paraguay
- Volunteers
- 50 people
- Sponsor
- Neurotronic, Inc.
Diabetes Mellitus Type 2
Advance Health Mobile APP for the Self Management of Diabetes type2
Digital health using mobile health (mHealth) tools, such as telehealth and text messaging, and or mobile Apps can improve blood glucose levels in patients with type 2 diabetes.
- Trial name
- NCT06614283
- Testing
- Diabetes self management @ click
- Where
- Pakistan
- Volunteers
- 1,600 people
- Sponsor
- Universiti Putra Malaysia
Type 2 Diabetes
To Assess Safety, Tolerability, Pharmacokinetics/Pharmacodynamics and the Effect of Fasting After Single Oral Doses of AZD5658 in Type 2 Diabetes
The purpose of this study is to investigate the safety and tolerability of AZD5658 following ascending single oral doses in Type 2 Diabetics. It will also estimate the maximum tolerated dose.
- Trial name
- NCT01176097
- Testing
- AZD5658
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Hypertension Associated, Type II Diabetes Mellitus
Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension
The purpose of this study is to evaluate the efficacy and safety of Atenas association in the treatment of type 2 diabetes mellitus and hypertension
- Trial name
- ATENAS (NCT05144360)
- Testing
- Atenas
- Sponsor
- EMS
Diabetes Mellitus, Type 2
A Double-Blind, Randomized, Parallel, Comparative Study to Evaluate the Efficacy and Safety of an Antidiabetic Agent Repaglinide for the Treatment of Type 2 Diabetes Mellitus Patients
The purpose of this study is to determine whether a new-brand of repaglinide is effective in the treatment of type 2 diabetes patients.
- Trial name
- NCT00336310
- Testing
- Repaglinide
- Where
- 2 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng-Kung University Hospital
Type 2 Diabetes Mellitus
Vildagliptin Compared to Gliclazide as Dual Therapy With Metformin in Muslim Patients With Type 2 Diabetes Fasting During Ramadan
To evaluate vildagliptin as compared to gliclazide, given in combination with metformin in Muslim patients with type 2 diabetes fasting during Ramadan.
- Trial name
- STEADFAST (NCT01758380)
- Testing
- Vildagliptin, Gliclazide, Metformin
- Where
- 68 sites in Denmark, Egypt and 14 more
- Volunteers
- 557 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus
Diabetes Effects on Long-Term Implant Survival and Success
This study is designed to understand the impact of glycemic control in patients with type 2 diabetes on dental implants under long-term function.
- Trial name
- NCT02282046
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Type 2 Diabetes Mellitus
Pilot Study of the Effects of Erythritol on Endothelial Function in Patients With Type 2 Diabetes Mellitus
The study will determine whether acute and chronic consumption of a beverage containing erythritol will improve endothelial function in patients with type 2 diabetes mellitus.
- Trial name
- NCT01609088
- Testing
- Erythritol-containing beverage
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston University
Cardiovascular Diseases, Metabolic Syndrome
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Obesity, Prediabetes
- Trial name
- NCT07106879
- Testing
- Blood Work
- Where
- United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Clindove Research LLC
Type 2 Diabetes, Overweight (BMI > 25)
HIIE and Abdominal Fat Mass in DT2 Postmenopausal Women
Postmenopausal women, as men, are more prone to central or android obesity. Abdominal fat mass is associated with an increase of cardiovascular diseases (CVD).
- Conditions
- Type 2 Diabetes, Overweight (BMI > 25), Postmenopausal Women
- Trial name
- NCT02352246
- Testing
- Physical activity programs steady-state exercise (SSE) program, Physical activity programs high intensity intermittent exercise (HIIE)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Type 2 Diabetes Mellitus
Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin
The purpose of this study is to demonstrate the safety and tolerability of dutogliptin over 52 weeks.
- Trial name
- NCT00998686
- Testing
- dutogliptin, sitagliptin
- Where
- 44 sites in United States, Argentina and 4 more
- Volunteers
- 650 people
- Sponsor
- Phenomix
Diabetes Mellitus, Type 2
A Study to Compare the Effect of Giving Dulaglutide Using an Auto-injector Versus a Manual Syringe
The study involves 2 injections of 1.5 milligrams (mg) dulaglutide, 1 given by a pre-filled manual syringe, the other given by an auto-injector. Injections will be separated by a minimum 28-day washout period.
- Trial name
- NCT01524770
- Testing
- Dulaglutide
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus (T2DM)
A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
The main purpose of this study is to assess the dose-response relationship of maridebart cafraglutide on glucose control compared with placebo.
- Trial name
- NCT06660173
- Testing
- Maridebart Cafraglutide
- Where
- 96 sites in United States, Austria and 12 more
- Volunteers
- 409 people
- Sponsor
- Amgen
Diabete Type 2, Obesity & Overweight
Artichoke By-products Rich in Hydroxycinnamic Acids and Mediterranean Diet for Type 2 Diabetes Prevention.
The ARTI-UP study evaluates whether daily consumption of a supplement made from artichoke by-products, rich in hydroxycinnamic acids (HCAs), in combination with an energy-restricted Mediterranean diet (erMeDiet), can improve…
- Conditions
- Diabete Type 2, Obesity & Overweight, Insulin Resistance Syndrome
- Trial name
- ARTI-UP (NCT07415720)
- Testing
- Artichoke by-product capsules, Energy-restricted Mediterranean diet (erMeDiet), Physical activity
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Diabetes Mellitus, Type 2
Effectiveness of Glucose Control, β Cell Function in Response to Short-term Insulin Pump Therapy in Type 2 Diabetes
The purpose of this study is to investigate and evaluate the significance of intravenous glucose tolerance test in assessment of β-cell function improvement after short course of intensive insulin therapy, trying to illustrate…
- Trial name
- NCT03509324
- Testing
- Insulin LISPRO
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Sun Yat-sen University
Obesity, Overweight
A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes
This study will investigate the safety and efficacy of once daily oral treatment with orforglipron compared with placebo on body weight in adult participants with obesity or overweight and type 2 diabetes.
- Conditions
- Obesity, Overweight, Type 2 Diabetes
- Trial name
- ATTAIN-2 (NCT05872620)
- Testing
- Orforglipron
- Where
- 136 sites in United States, Argentina and 9 more
- Volunteers
- 1,613 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type II
Study of Effectiveness of Liraglutide Added to High Dose Insulin in Type II Diabetics
The purpose of this study is to determine the effect of adding liraglutide to high dose insulin therapy compared to high dose insulin therapy alone in patients with insulin-treated Type 2 diabetes with insulin requirements of >…
- Trial name
- NCT01654120
- Testing
- Liraglutide, Insulin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mountain Diabetes and Endocrine Center