Clinical trials: Type2diabetes
Small for Gestational Age at Delivery, Gestational Diabetes
The CanDo (Canadian Donor Milk) Trial
The goal of this clinical trial is to learn about the impact of donor milk vs formula supplementation on human milk feeding and the health outcomes of infants who require supplementation in well-baby units.
- Conditions
- Small for Gestational Age at Delivery, Gestational Diabetes, type1diabetes, Type2diabetes
- Trial name
- NCT06315127
- Testing
- Human donor milk, Formula
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Mount Sinai Hospital, Canada
Hypertension, Type2diabetes
Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
This study is a human-centered, three-arm, parallel-group, randomized control, implementation trial (n=75) to compare MTM (Medically Tailored Meals) only (14 meals delivered weekly for 10 weeks) vs.
- Conditions
- Hypertension, Type2diabetes, Metabolic Syndrome, Obesity
- Trial name
- NOURISH HEARTS (NCT06460272)
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Amanda Shallcross
Type2diabetes, Enhanced Recovery After Surgery (ERAS)
Preoperative Carbohydrate Loading in Diabetes Mellitus
This prospective, randomized, open-label, parallel-group clinical trial aims to evaluate the safety and metabolic effects of preoperative carbohydrate loading in patients with well-controlled type 2 diabetes mellitus (T2DM)…
- Conditions
- Type2diabetes, Enhanced Recovery After Surgery (ERAS), Fasting, Carbohydrate Loading
- Trial name
- PRECARB-DMP (NCT07237841)
- Testing
- 25% Carbohydrate solution (CHO drinking)
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- Gia Dinh People Hospital
Chronic Kidney Diseases, Type2Diabetes
Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus
While data from the National Health and Nutrition Examination Survey (NHANES) estimate that 36.9% of patients with diabetes have CKD, only approximately 10% of patients are aware of their kidney disease.
- Trial name
- CKD-DETECT (NCT05342545)
- Testing
- Alert-based computerized decision support
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Brigham and Women's Hospital
Prevention, Type2Diabetes
Dialectal Behaviour Therapy to Enhance Health Behaviour Change for Adolescents Living With Obesity (DIRECTION Trial)
This research is being conducted to evaluate emotion-focused therapy that incorporates elements of mindfulness, distress tolerance, and relationship support.
- Trial name
- NCT05338944
- Testing
- Dialectical behavioral therapy, Lifestyle
- Where
- 3 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Overweight and Obesity, Type2diabetes
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
The purpose of this study is to evaluate the safety, tolerability and drug levels of an exenatide implant administered subcutaneously.
- Trial name
- LIBERATE-1 (NCT05670379)
- Testing
- Exenatide Implant, Bydureon BCise (exenatide extended release), Semaglutide, 1.0 mg/mL
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vivani Medical, Inc
Obesity, Type2diabetes
Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE"
Obesity is a life-threatening disease, defined by excessive fat accumulation that increases the risk of other diseases such as cardiovascular events, hypertension, diabetes and cancer.
- Conditions
- Obesity, Type2diabetes, Lipodystrophy, Infections
- Trial name
- SIDERALE2020 (NCT06236932)
- Testing
- Mediterranean diet, Melatonin supplementation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Type2diabetes
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes
Type 2 diabetes and metabolic (dysfunction)-associated fatty liver disease (MAFLD) often exist together. The prevalence of MAFLD is about 15-30% in healthy people and around 60-70% in people with type 2 diabetes.
- Trial name
- NCT06289387
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Medanta, The Medicity, India
Type2diabetes, Heart Failure With Preserved Ejection Fraction
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome.
- Trial name
- NCT06337812
- Testing
- Potato Starch
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Type2diabetes, Obesity
Depletion of Liver Fat in Type 2 Diabetes
The aim of this randomized trial is to determine whether liver fat depletion via a short-term (i.e., two weeks) very-low calorie diet will restore the normal exercise-induced secretion of a signaling protein (fibroblast growth…
- Trial name
- DepLiv (NCT06211556)
- Testing
- Very-low calorie diet
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type2diabetes, Disordered Eating
ARIADNE: A Study of Weight Loss for Diabetes Treatment and Wellbeing
The NHS has started a trial-run of a weight loss programme replacing food with 800-calorie shakes and soups for 3 months, offered to people with newly diagnosed type 2 diabetes (T2D) to lose weight and put their diabetes into…
- Conditions
- Type2diabetes, Disordered Eating, Obesity, Overweight and Obesity
- Trial name
- NCT05744232
- Testing
- Low calorie total diet replacement, Usual care
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Type2diabetes
Effects of the General Practitioners and Diabetes Specialists Co-management Model for Patients With Type 2 Diabetes
This is a prospective, randomized, parallel, multicenter controlled study to evaluate the effectiveness of the general practitioners and diabetes specialists co-management model for type 2 diabetes.
- Trial name
- NCT05556161
- Testing
- General Practitioners and Diabetes Specialists Co-management
- Where
- China
- Volunteers
- 609 people
- Sponsor
- Huazhong University of Science and Technology
Type2diabetes
Early Identification of Heart Failure in a High-Risk Diabetic Cohort
Type 2 diabetes is an important co-morbid condition strongly associated with the risk of developing heart failure (HF). Risk scores such as the WATCH-DM score that predict the occurrence of HF among diabetes patients are largely…
- Trial name
- NCT05866380
- Testing
- heart failure risk factors
- Where
- Taiwan
- Volunteers
- 3,500 people
- Sponsor
- Mackay Memorial Hospital
Type2diabetes
Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control
In this study, we aim to explore the beneficial effect of early short-term (two weeks), self-titrated, basal-only insulin therapy on the degree of glycemic control over 1-year follow through a prospective cohort.
- Trial name
- NCT06107153
- Testing
- Insulin Glargine 100 UNT/ML Pen Injector [Lantus], Saxagliptin 2.5 mg/ Metformin Hydrochloride extended release 1000 mg, Pioglitazone 30mg
- Where
- Iraq
- Volunteers
- 243 people
- Sponsor
- University of Basrah
Type1diabetes, Type2diabetes
Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes Mellitus
The goals of this project are to build an experimental tool to dissect out in vivo pancreatic beta cell mass (BCM) and beta cell function (BCF) and to assess for the first time these two determinants of beta cell functional mass…
- Conditions
- Type1diabetes, Type2diabetes, Pre Diabetes, Hyperinsulinism
- Trial name
- NCT05662189
- Testing
- 68Ga-exendin-4, mixed meal test
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Type2diabetes
DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
Key finding of DM Treatment with combination, A MuLticenter, Randomized, Parallel, Gathering Information of phase 4 Trial to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone add-on to Metformin and DPP-4…
- Trial name
- KLIMT (NCT06875193)
- Testing
- DW6012(Dasidiem tab. 10/100mg)
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Type2diabetes
Combination of Henagliflozin and Continuous Subcutaneous Insulin Infusion in T2DM
The Multi-center, randomized, controlled clinical trial investigate the efficacy and safety of Henagliflozin combined with continuous subcutaneous insulin infusion in newly diagnosed type 2 diabetes
- Trial name
- NCT05677334
- Testing
- Henagliflozin, Continuous Subcutaneous Insulin Infusion
- Where
- China
- Volunteers
- 210 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Type2diabetes, Hypoglycemia
The Effectiveness of Multimedia Education on Hypoglycemic Management.
The first phase of the research was to develop tools, including scales and multimedia, and the second phase was to carry out multimedia hypoglycemia education intervention measures.
- Trial name
- NCT06516705
- Testing
- Hypoglycemia education
- Where
- Taiwan
- Volunteers
- 83 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Type2diabetes
FreeStyle Libre Monitoring in T2DM
The goal of this clinical trial is to learn if blood sugar monitoring using a FreeStyle Libre device can improve overall Diabetes control in people with Type 2 Diabetes.
- Trial name
- NCT05597293
- Testing
- Glucose monitoring using FreeStyle Libre 2, Glucose monitoring using FreeStyle Libre pro iQ
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Hull
Type2diabetes
Exercise Training and Type 2 Diabetes
Objective: This study investigates the effects of hybrid training in the form of small-sided football games on health status, blood glucose regulation, muscle metabolism, and well-being in patients with type 2 diabetes mellitus…
- Trial name
- NCT06478173
- Testing
- Exercise training
- Where
- Faroe Islands
- Volunteers
- 126 people
- Sponsor
- University of the Faroe Islands