Clinical trials: URTI
Respiratory Syncytial Virus Infections
Study to Evaluate the Incidence of Hospitalizations and Respiratory Tract Infections in Premature Infants
The purpose of this study is to describe respiratory syncytial virus (RSV) hospitalization rates and to begin to address the utilization of outpatient resources for RSV medically-attended lower respiratory tract infections…
- Trial name
- NCT00384462
- Where
- 59 sites in United States
- Volunteers
- 346 people
- Sponsor
- MedImmune LLC
Coronavirus Disease, SARS-CoV-2 Infection
ImmuneSense™ COVID-19 Cross-Reactivity Study
Adaptive Biotechnologies has developed a clinical test called T-Detect COVID Test that can identify a T-cell response to the SARS-CoV-2 virus, indicating recent or prior infection This study aims to evaluate the potential…
- Trial name
- NCT05112874
- Where
- United States
- Sponsor
- Adaptive Biotechnologies
Respiratory Tract Infections
ProbioKid as Prevention Among Kids With Frequent URTI
This study was designed to evaluate the preventive efficacy of a 6-week prophylactic administration of Probiokid® on the incidence of respiratory infections and related complications in frequently sick children.
- Trial name
- NCT04525040
- Testing
- ProbioKid®, Pragmatic comparator
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Viral Pharyngitis
Effect of Cetylpyridinium Chloride (CPC) Rinse in Viral Upper Respiratory Tract Infections (vURTI)
This is a randomized, controlled clinical trial with two parallel groups in which 150 volunteers (75 per group) will receive either VITIS CPC Protect® mouthwash (Mouthwash with cetylpyridinium chloride (CPC) as an anti-plaque…
- Trial name
- NCT06251089
- Testing
- CPC mouthwash
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dentaid SL
Cryopyrin Associated Periodic Syndrome
A Study to Evaluate VTX2735 in Patients With Cryopyrin-associated Periodic Syndrome
This is a study to understand if taking VTX2735 is safe and effective in participants diagnosed with Cryopyrin-Associated Period Syndrome (CAPS). Approximately 10 patients will take VTX2735 Dose A or VTX2735 Dose B.
- Trial name
- Explore (NCT05812781)
- Testing
- VTX2735
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Zomagen Biosciences Ltd.
Lower Resp Tract Infection
Prospective Clinical Evaluation of the FilmArray® Lower Respiratory Tract Infection (LRTI) Panel
This is a performance study to test the sensitivity and specificity of the BioFire FilmArray Lower Respiratory Tract Infection (LRTI) Panel.
- Trial name
- LRTI (NCT03361670)
- Testing
- Observational Study
- Where
- 8 sites in United States
- Volunteers
- 1,689 people
- Sponsor
- BioFire Diagnostics, LLC
Cold
Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold
The primary objective of this study is to evaluate the non-inferiority of Coristina® d in the symptomatic treatment of the common cold compared to Resfenol® comparator.
- Trial name
- NCT02735070
- Testing
- Resfenol, Coristina d
- Volunteers
- 366 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Cold Agglutinin Disease
A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Without A Recent History of Blood Transfusion
The purpose of Part A was to determine whether sutimlimab administration resulted in a greater than or equal to (>=)1.5 grams per deciliter (g/dL) increase in hemoglobin (Hgb) level and avoidance of transfusion in participants…
- Trial name
- Cadenza (NCT03347422)
- Testing
- sutimlimab (BIVV009)
- Where
- 53 sites in United States, Australia and 12 more
- Volunteers
- 42 people
- Sponsor
- Bioverativ, a Sanofi company
Acute Upper Respiratory Tract Infections, Bronchitis
Therapeutic Confirmatory Clinical Trial to Evaluate the Safety and Efficacy of "AG NPP709 Syrup"
The purpose of this study is to assess therapeutic confirmation of AG NPP709 syrup to evaluate the safety and efficacy in patients with acute upper respiratory tract infection and chronic inflammatory bronchitis.
- Trial name
- NCT01151202
- Testing
- AG NPP709syrup
- Where
- 6 sites in South Korea
- Volunteers
- 236 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
RSV Infection, Stem Cell Transplant Complications
Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV
RV521 is to being developed to treat RSV infection and disease in susceptible individuals at high risk for complications. This is an international, multicenter, placebo-controlled study.
- Conditions
- RSV Infection, Stem Cell Transplant Complications, Lower Resp Tract Infection
- Trial name
- REVIRAL2 (NCT04267822)
- Testing
- RV521 oral tablet
- Sponsor
- Pfizer
Infections, Upper Respiratory Tract
The Effect of a Probiotic on Upper Respiratory Tract Infections
This study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group study in healthy children aged 2-6 years.
- Trial name
- PIP-U (NCT03636191)
- Testing
- Probiotic strain
- Where
- United Kingdom
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Healthy
A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Safety and Tolerability of Influenza Virus Vaccine,(CAIV-T) in Healthy Infants
Trial to compare the safety and tolerability of one and two doses of influenza virus vaccine.
- Trial name
- NCT00192348
- Testing
- CAIV-T
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Warm Autoimmune Hemolytic Anemia, Cold Agglutinin Disease
Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With Warm Type Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)
This study is to assess the safety, tolerability, preliminary efficacy, and pharmacokinetics of APL-2 in subjects with warm Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD).
- Trial name
- NCT03226678
- Testing
- APL-2
- Where
- 8 sites in United States
- Volunteers
- 24 people
- Sponsor
- Apellis Pharmaceuticals, Inc.
Hypothermia Due to Cold Environment
Clinical Evaluation of Effectiveness of the "Therm'Up" Heating Device
Here's a concise summary in English without the numbers: Hypothermia is defined as a core temperature below 35°C and occurs when the body loses more heat than it produces.
- Trial name
- NCT06788925
- Testing
- Patients support with survival coverage, Patients support with active thermic jacket
- Where
- France
- Volunteers
- 100 people
- Sponsor
- ThermoTrauma
Flu, Cold
Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal
The common cold is a major cause of nasal obstruction and reaches children and adults two or more times a year. At the moment, there is no cure for the common cold, and therefore the reduction of symptoms is the focus of the…
- Conditions
- Flu, Cold, Allergic Disorder of Respiratory System
- Trial name
- NCT01533220
- Testing
- naphazoline hydrocloride, Naphazoline hydrocloride + Pheniramine Maleate + Panthenol
- Volunteers
- 132 people
- Sponsor
- EMS
Upper Respiratory Tract Infections
Trulimax (Azithromycin ) Non-Interventional Study In Acute Bacterial Upper Respiratory Tract Infections
To assess effectiveness of Trulimax (Azithromycin) in Acute Bacterial Upper Respiratory Tract Infections (URTIs).
- Trial name
- NCT00827502
- Where
- 11 sites in India
- Volunteers
- 421 people
- Sponsor
- Pfizer
Common Cold
Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides)
The aim of the study is to evaluate the safety of the intake of EPs® 7630 during a long-term (4 months) medication. The protective effects of EPs®7630 and its effects during a cold episode will also be studied.
- Trial name
- NCT02174653
- Testing
- EPs® 7630
- Where
- United Kingdom
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Dr. Willmar Schwabe GmbH & Co. KG
Respiratory Syncytial Virus Infections
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.
The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy preterm infants who are between 29 and 35 weeks gestational age (GA) and entering…
- Trial name
- MEDI8897 Ph2b (NCT02878330)
- Testing
- MEDI8897
- Where
- 161 sites in United States, Argentina and 21 more
- Volunteers
- 1,453 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Respiratory Syncytial Virus
A Study to Assess the Safety, Tolerability, and Immunogenicity of RSVpreF in Older Adults in Korea
The goal of this clinical trial is to quantify the immune response in older Korean adults after a RSVpreF vaccination. It will also learn about the safety and tolerability of RSVpreF vaccination.
- Trial name
- NCT06593587
- Testing
- RSVpreF Vaccine
- Where
- 16 sites in South Korea
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteer, URTI
LC-Plasma for Preventing URTIs and Reducing Symptoms
The goal of this study is to evaluate the efficacy of the LC-Plasma in preventing upper respiratory tract infections (URTIs) in healthy volunteers. Researchers will compare LC-Plasma to placebo to see if LC-Plasma prevents URTIs.
- Trial name
- NCT06827327
- Testing
- LC-Plasma
- Where
- Australia
- Volunteers
- 637 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd