Clinical trials: URTI
Hemorrhage, Platelets; Defect
Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients
This trial is being performed to evaluate the feasibility of the study protocol and to test the efficacy and safety of platelets stored at cold conditions (1-6°C) in 100% plasma for 10-14 days (CSP) in cardiac surgery patients…
- Conditions
- Hemorrhage, Platelets; Defect, Bleeding, Surgical Blood Loss
- Trial name
- CHASE (NCT05220787)
- Testing
- Cold stored platelets in 100% plasma stored for 10-14 days, Room temperature stored platelets in 100% plasma stored for up to 7 days
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Moritz Stolla, MD
Acute Upper Respiratory Tract Infections
Trial of Post-Dated Delayed Antibiotic Prescriptions
Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral). This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2…
- Trial name
- NCT02732847
- Testing
- A delayed prescription dated 2 days after clinical office visit, Usual Dated
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- Memorial University of Newfoundland
Respiratory Tract Diseases
Study of Echinaforce Junior Tablets in Children With Acute Colds
This study aims to investigate safety and efficacy of Echinaforce Junior tablets in two dosages of 3 x 1 and 5 x 1 tablets per day in children 4 - 12 years old with acute colds.
- Trial name
- NCT02198391
- Where
- Switzerland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Cardiovascular System
Acute Effects of Cold Exposure on Cardiovascular System
This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.
- Trial name
- NCT06652425
- Testing
- Low temperature (15°C) group, Moderate temperature (22°C) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Acne Vulgaris
Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study
Acne vulgaris is a common, chronic inflammatory skin disease with complex pathogenesis and limited therapeutic options, especially for moderate-to-severe cases.
- Trial name
- NCT07056673
- Testing
- Active CAP therapy, standard care based on the JAAD acne guidelines
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Shenyang Medical College
Common Cold
The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza.
This phase IV multi-centre, randomised, double-blind, placebo-controlled, parallel-group, single-dose study will assess the efficacy and tolerability of the active tablets versus placebo in participants suffering from cold and…
- Trial name
- NCT02246166
- Testing
- Test tablet
- Where
- 2 sites in China
- Volunteers
- 53 people
- Sponsor
- GlaxoSmithKline
Particularly Partial-body Cryostimulation
Effect of Cryostimulation on Selected Motor Skills in Soccer Players
A randomized study was conducted during two training periods. The first stage of a 5-day cryostimulation procedure took place in November 2022, during the training period after the end of the league season.
- Trial name
- NCT06812819
- Testing
- Cryostimulation is a form of cooling the body using low temperatures without causing tissue damage. The stimulus effect is achieved at temperatures below - 110⁰C, in a short time of 1-3 minutes. The p
- Where
- Poland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Obesity
Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures
This study will examine how body metabolism adjusts to small changes in environmental temperature and how it may be related to weight loss.
- Trial name
- NCT00521729
- Testing
- Exposure to Cold Temperature
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Subdural Hematoma, Subdural Hematoma
Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma
The goal of this randomized controlled trial is to evaluate whether the adjuvant application of non-thermal plasma (NTP) during standard surgical drainage of chronic subdural hematoma (cSDH) can reduce the recurrence rate at 6…
- Conditions
- Chronic Subdural Hematoma, Subdural Hematoma, Recurrence, Postoperative Complications
- Trial name
- NCT07656818
- Testing
- Standard Surgery Protocol, Non-Thermal Plasma
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Residual Disease
R0 Resection Rate Between CSP, cEMR and hEMR for 1-2 cm Colorectal SSLs
Colorectal cancer is the most prevalent cancer and the third cancer related death in Taiwan. Adenoma is a precancerous lesion of colorectal cancer.
- Trial name
- NCT05117879
- Testing
- Cold snaring polypectomy/ Cold EMR/Hot EMR
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Cold Therapy
Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?
The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction.
- Trial name
- NCT07370870
- Testing
- Cold Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Coronary Artery Disease
Year-round Health Enhancing Exercise and Coronary Artery Disease
A cold season involves higher cardiovascular morbidity and mortality. Several epidemiologic studies have implicated that persons with a cardiac disease, such as coronary artery disease (CAD) may be at higher risk for these…
- Trial name
- NCT02855905
- Testing
- Exercise/Rest and cold/neutral temperature
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- University of Oulu
Common Cold, Healthy
Efficacy Study of A Lotion to Prevent Common Colds
The purpose of this of this study is to determine if 3804-250A can prevent the common cold caused by the rhinovirus when applied to the hands.
- Trial name
- NCT00993759
- Testing
- 3804-250A
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- The Dial Corporation
Analgesic Effects of Music
The Sedative Effects of Music Listening on Pain During Cold Pressor Test
This study aims to understand whether listening to music can reduce pain and anxiety caused by a cold-temperature stimulus in healthy young adults (n = 30).
- Trial name
- ESEMP (NCT07515196)
- Testing
- Phase 1 - Silence (Baseline), Phase 2 - Happy Mode with Measured Rhythm, Phase 3 - Sad Mode with Measured Rhythm
- Where
- Lebanon
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rawane El Dimachki
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
URTI - Viral Upper Respiratory Tract Infection
A Study to Assess the Effect Probiotic Supplement on Immune Health in Teachers Prone to Upper Respiratory Tract Infection
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical studydesigned to assess the effects of IP on immune health in teachers prone to URTI.
- Trial name
- NCT07033754
- Testing
- Propionibacterium freudenreichii P.UF1, Microcrystalline cellulose, calciumcarbonate, Mg Stearate, Sylysia
- Where
- 6 sites in India
- Volunteers
- 100 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Coronavirus Disease, SARS-CoV-2 Infection
ImmuneSense™ COVID-19 Cross-Reactivity Study
Adaptive Biotechnologies has developed a clinical test called T-Detect COVID Test that can identify a T-cell response to the SARS-CoV-2 virus, indicating recent or prior infection This study aims to evaluate the potential…
- Trial name
- NCT05112874
- Where
- United States
- Sponsor
- Adaptive Biotechnologies
Familial Adenomatous Polyposis
Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
The purpose of this study is to collect prospective observational data regarding patients with diagnosed Familial Adenomatous Polyposis (FAP) undergoing cold snare polypectomy for duodenal adenomas
- Trial name
- COPDA (NCT03471403)
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Western Sydney Local Health District
Raynaud Disease, Hyperemia
PORH and Response to Cold in Raynaud's Phenomenon.
The main objective of the study is to determine if implication of epoxy-eicosatriénoïc acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by…
- Conditions
- Raynaud Disease, Hyperemia, Cold
- Trial name
- REFRAIN (NCT02183779)
- Testing
- post-occlusive hyperemia, cooling box, L-NMMA and Fluconazole dermic injection
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Lower Respiratory Tract Infection, Ventilator Associated Pneumonia
RASCALS: Rapid Assay for Sick Children With Acute Lung Infection Study
Lower Respiratory Tract infections are a common cause of admission to the intensive care unit. Children routinely receive antibiotics until the tests confirm whether the infection is bacterial or viral.
- Conditions
- Lower Respiratory Tract Infection, Ventilator Associated Pneumonia, COVID19
- Trial name
- RASCALS (NCT04233268)
- Testing
- Rapid Pathogen Detection
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust