Clinical trials: Ulcer, Gastric
Reflux Esophagitis
Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical Outcomes
The objective of this investigation is to collect following data in patients given NEXIUM capsule (NEXIUM) in usual post-marketing use.
- Trial name
- NCT02477475
- Where
- 47 sites in Japan
- Volunteers
- 1,595 people
- Sponsor
- AstraZeneca
Esophagitis Peptic
A Study on Vonoprazan in the Real-world Clinical Practice in China
The purpose of this study is to evaluate the safety of Vonoprazan by assessing all adverse events (AEs), serious adverse events (SAEs), and adverse drug reactions (ADRs) in routine clinical settings in China.
- Trial name
- VIEW (NCT04501627)
- Where
- 40 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Takeda
Peptic Ulcer Bleeding, Hypoalbuminemia
The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia
To test whether intravenous albumin can decrease the rebleeding rate or shorten the duration of hospitalization in patients with peptic ulcer bleeding and hypoalbuminemia.
- Trial name
- NCT01822600
- Testing
- Human albumin, Omeprazole
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Cheng-Kung University Hospital
Complications, Quality of Life
Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy
Gastric cancer as one of the most common gastrointestinal cancers, radical resection of primary lesions combined with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Complications, Quality of Life, Remnant Gastritis, Reflux Esophagitis
- Trial name
- DTA>A (NCT02288728)
- Testing
- Gastric tube anastomosis, Double-track anastomosis
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Jian-Kun Hu
Esophagitis, Reflux, Esophagitis, Peptic
Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis
The purpose of this study is to assess the ability of once-daily (QD) treatment with dexlansoprazole modified release (MR) 30 mg and 60 mg or placebo in maintaining healing of erosive esophagitis (EE).
- Trial name
- NCT00321737
- Testing
- Dexlansoprazole MR
- Where
- 98 sites in United States, Australia and 6 more
- Volunteers
- 445 people
- Sponsor
- Takeda
Healthy Volunteers
Study to Evaluate the Interaction Between Aspirin and Nexium
The purpose of this study is to assess the interaction between aspirin and Nexium in healthy volunteers.
- Trial name
- NCT01199328
- Testing
- Aspirin, Esomeprazole
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Platelet-rich Plasma, Endoscopic Submucosal Dissection
Healing Effects of Autologous Platelet Rich Plasma on Gastric Ulcer Caused by Endoscopic Submucosal Dissection
In Korea, where the prevalence of gastric tumors is high, the use of ESD as a treatment for gastric cancer will continue to increase.
- Trial name
- NCT03220334
- Testing
- Platelet rich plasma, Normal saline
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Keimyung University Dongsan Medical Center
Gastric Ulcer
Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen
This study uses a randomized, double-blind, controlled design to demonstrate that PN400 (esomeprazole and naproxen) is more effective in reducing the occurrence of gastroduodenal ulcers, dyspepsia, and heartburn in subjects at…
- Trial name
- NCT01129011
- Testing
- PN400 (VIMOVO), Naproxen
- Volunteers
- 420 people
- Sponsor
- POZEN
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine-containing quadruple therapy(berberine, lansoprazole, bismuth and amoxicillin) versus clarithromycin-containing quadruple therapy (clarithromycin,lansoprazole…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT02633930
- Testing
- Berberine, clarithromycin, Bismuth
- Where
- 2 sites in China
- Volunteers
- 566 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastritis, Gastroduodenal Ulcer
Effect of ALBIS on Gastroduodenal Mucosal Injury in Patients Receiving Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
The purpose of this study is to evaluate effectiveness of ALBIS on Gastroduodenal Mucosal Injury in Patients Receiving Dual Antiplatelet Therapy after Percutaneous Coronary Intervention.
- Trial name
- DAPTALBIS (NCT02175186)
- Testing
- ALBIS
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Young-Hak Kim, MD, PhD
Peptic Ulcer
Natural History of Non-steroidal Anti-inflammatory Drug and Non-Helicobacter Pylori in Bleeding Peptic Ulcers
The aim of this study is to study the natural history of the ulcer healing while on proton pump inhibitors (PPI) and the ulcer recurrence without acid suppression therapy of Non-steroidal Anti-inflammatory Drugs (NSAID)…
- Trial name
- NCT00153712
- Where
- China
- Volunteers
- 391 people
- Sponsor
- Chinese University of Hong Kong
Gastric Adenocarcinoma, Adenocarcinoma of the Esophagogastric Junction
Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction
This two-center retrospective observational cohort study compares Chinese and Russian patients who underwent curative proximal gastrectomy with double-tract reconstruction for proximal gastric adenocarcinoma or Siewert type…
- Trial name
- RUSCHI-DTR (NCT07800819)
- Testing
- Proximal gastrectomy with double-tract reconstruction
- Where
- 2 sites in China, Russia
- Volunteers
- 250 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Peptic Ulcer, NSAID-Induced Peptic Ulcer
Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice
This study is a prospective, multi-center, observational study to evaluate the efficacy and safety of Fexuclue Tablet 20 mg in patients requiring prevention of NSAIDs-induced peptic ulcer in real-world clinical practice in Korea.
- Trial name
- NCT07558707
- Where
- South Korea
- Volunteers
- 7,000 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Ulcerative Colitis, Inflammatory Bowel Diseases
Effects of Exercise in Patients With Ulcerative Colitis
The aim of this study is to investigate the effects of moderate to high intensity exercise on gut function and inflammatory markers in patients with Ulcerative Colitis (UC), and to compare them with individuals of matched age who…
- Trial name
- NCT04143490
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Perforated Peptic Ulcer
Open vs Laparoscopic Repair of Perforated Peptic Ulcer
comparison between outcomes of both open and laparoscopic repair of perforated peptic ulcer
- Trial name
- NCT05767320
- Testing
- open repair(exploration), abdominal laparoscopy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bleeding Peptic Ulcer
The Use of OTSC in LBGDU to Standard Endoscopic Hemostatic Methods
In managing bleeding gastroduodenal ulcers, endoscopic control of bleeding is the first line treatment-further bleeding after endoscopic hemostasis is associated with a 3-fold increase in mortality.
- Trial name
- OTSC-LBGDU (NCT06196710)
- Testing
- Over-the-scope Clips, Hemo-clipping
- Sponsor
- Chinese University of Hong Kong
Peptic Ulcer Hemorrhage
Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding
Peptic ulcer bleeding is a common emergency for patients who need therapeutic endoscopy. According to international guidelines and Taiwan consensus, the standard therapy included proton pump inhibitor (PPI) and endoscopic…
- Trial name
- NCT05248321
- Testing
- Tranexamic Acid Powder
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Functional Pancreatic Neuroendocrine Tumor, Malignant Somatostatinoma
Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor
This phase I trial studies the side effects and best dose of veliparib when given together with capecitabine and temozolomide in treating patients with neuroendocrine tumor that has spread to other places in the body and usually…
- Conditions
- Functional Pancreatic Neuroendocrine Tumor, Malignant Somatostatinoma, Merkel Cell Carcinoma, Metastatic Adrenal Gland Pheochromocytoma
- Trial name
- NCT02831179
- Testing
- Capecitabine, Temozolomide, Veliparib
- Sponsor
- Vanderbilt-Ingram Cancer Center