Clinical trials: Ulcer Venous
Venous Insufficiency, Leg Ulcer
The Evaluation of OrCel for the Treatment of Venous Ulcers
This study was designed to confirm the clinical benefits and safety of OrCel in the treatment of venous ulcers. OrCel and standard care are compared to standard care alone.
- Trial name
- NCT00270972
- Testing
- Bilayered Cellular Matrix (OrCel)
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Ortec International
Leg Ulcers
Assessment of Efficacy & Safety for a New Wound Dressing Urgo 310 3166 in the Local Treatment of VLU or Mixed Leg Ulcers
Assessment of efficacy and safety for a new wound dressing URGO 310 3166 in the local treatment of venous or mixed leg ulcers: a European, randomised clinical trial.
- Trial name
- NCT02583958
- Testing
- Urgo 3103166, Aquacel Extra
- Where
- France
- Sponsor
- Laboratoires URGO
Venous Ulcer
Venous Ulcer Treatment With Foam Versus Conservative Treatment
The venous ulcer due to venous insufficiency causes an important morbility to those people suffering from this condition. Most of therapies available under the obligatory health plan (POS, acronym in spanish) to date cover the…
- Trial name
- VUTEF (NCT01594658)
- Testing
- Foam sclerotherapy, conservative
- Where
- Colombia
- Volunteers
- 46 people
- Sponsor
- Hospital Occidente de Kennedy
Healthy Adults, Venous Leg Ulcer
Pressure and Temperature Sensor for Therapeutic Compression Garments
Pilot study of a soft, flexible pressure and temperature sensor
- Trial name
- NCT03461549
- Testing
- Pressure and Temperature Sensor
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Venous Ulcers
Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
The purpose of this study is to determine whether nitric oxide (NO)gas is effective in the treatment of venous ulcers of the lower leg.
- Trial name
- NCT00613808
- Testing
- Nitric Oxide 200ppm Group B
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Nitric BioTherapeutics, Inc
Venous Stasis Ulcer
Efficacy Study of the Application of Low Level Laser Light to Treat Venous Stasis Ulcers
The purpose of this study is to determine whether low level laser light therapy is effective as an adjunctive therapy to the healing of venous stasis leg ulcers.
- Trial name
- NCT01376050
- Testing
- Erchonia ML Scanner (MLS)
- Where
- 2 sites in United States, France
- Volunteers
- 24 people
- Sponsor
- Erchonia Corporation
Venous Leg Ulcer
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III)
The aim of this clinical trial is to investigate the efficacy and safety of allo-APZ2-CVU, administered topically on therapy-resistant non-healing CVUs compared to placebo.
- Trial name
- NCT06489028
- Testing
- allo-APZ2-CVU
- Where
- 15 sites in United States, Austria and 10 more
- Volunteers
- 250 people
- Sponsor
- RHEACELL GmbH & Co. KG
Venus Leg Ulcer (VLU), VLU
Borate-based Bioactive Glass Fiber Matrix (BBGFM) in the Treatment of Venus Leg Ulcers (VLU)
The goal of this clinical trial is to learn if Borate-based Bioactive Glass Fiber Matrix (BBGFM) can help heal Venous Leg Ulcers (VLU) that have not closed with standard treatment. The main question it aims to answer is: 1.
- Conditions
- Venus Leg Ulcer (VLU), VLU, Venus Leg Ulcer, Venus Ulcer
- Trial name
- NCT07647705
- Testing
- Borate Based Bioactive Glass Fiber Matrix (BBGFM)
- Volunteers
- 110 people
- Sponsor
- ETS Wound Care, LLC
Chronic Wound
Efficacy of RPh201 Applied Topically for the Treatment of Hard to Heal Chronic Ulcerated Wounds
The study objectives are to evaluate safety and efficacy of topical administration of RPh201 oil solution (botanical extract) for treatment of patients with hard to heal chronic ulcerated wounds.
- Trial name
- NCT01429519
- Testing
- RPh201, botanical drug product
- Where
- Israel
- Volunteers
- 4 people
- Sponsor
- Regenera Pharma Ltd
Venous Leg Ulcer, Venous Ulcer
Evaluation of the Efficacy of Multilayer Compression & UrgoStart Plus
Historically, venous leg ulcers have been very difficult to manage, with associated poor healing rates, and the likelihood of recurrence.
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Insufficiency of Leg, Leg Ulcer
- Trial name
- NCT06007703
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Venous Leg Ulcers
A Pilot Trial of the Use of ReCell® Autologous Cell Harvesting Device for Venous Leg Ulcers
This is a prospective, randomised, open label, controlled pilot study to evaluate the safety and preliminary effectiveness of the ReCell Autologous Cell Harvesting Device (ReCell) for the management of chronic leg ulcers…
- Trial name
- NCT01743053
- Testing
- Standard Care plus ReCell, Standard Care
- Where
- 7 sites in France, United Kingdom
- Volunteers
- 52 people
- Sponsor
- Avita Medical
Surgical Incision, Ulcer Foot
Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wounds
This is a prospective, multi-center, open label study evaluating the performance of PICO14 Negative Pressure Wound Therapy (NPWT) in the management of chronic open wounds (pressure ulcers, venous leg ulcers, diabetes related foot…
- Conditions
- Surgical Incision, Ulcer Foot, Ulcer Venous, Ulcer, Leg
- Trial name
- PICO14 (NCT05234632)
- Testing
- PICO 14 single-use Negative Pressure Wound Therapy System
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Smith & Nephew, Inc.
Venous Leg Ulcer (VLU)
A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance and Safety of a Soft Silicone Foam Dressing and to Evaluate the Performance of Standard Care in Exuding Venous Leg Ulcers
This investigation is a Post Marketing Follow-Up Study for Mepilex XT conducted as part of Mölnlycke Health Care's quality system.
- Trial name
- NCT02167815
- Testing
- Mepilex XT, standard care
- Where
- 3 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Molnlycke Health Care AB
Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg
Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering
The aim of this work was to compare the efficacy of intravenous (IV) tramadol versus magnesium sulphate added to 100 ml saline for prevention of shivering associated with spinal anesthesia.
- Conditions
- Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg, Hernia
- Trial name
- NCT06612996
- Testing
- Tramadol, Magnesium sulphate, Saline
- Volunteers
- 180 people
- Sponsor
- Al-Azhar University
Wound Healing, Diabetic Foot
EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds
Post-market study to determine the efficacy of EDX110 dressing system in hard-to-heal wounds.
- Conditions
- Wound Healing, Diabetic Foot, Foot Ulcer, Diabetic, Venous Ulcer
- Trial name
- NCT06640985
- Testing
- EDX110 wound dressing system
- Where
- Chile
- Volunteers
- 43 people
- Sponsor
- ConvaTec Inc.
Venous Leg Ulcer, Diabetic Foot
AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period
Study is to provide evidence comparing AQUACEL® Ag+ Extra™ versus Cutimed® Sorbact® in the progression of wounds towards healing
- Trial name
- NCT05892341
- Testing
- AQUACEL® Ag+ Extra™, Cutimed® Sorbact®
- Where
- 18 sites in Colombia, Germany and 1 more
- Volunteers
- 203 people
- Sponsor
- ConvaTec Inc.
Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher
Reducing Skin Tone Inequities in Chronic Venous Insufficiency
The aim of this project is to define assessment criteria for chronic venous insufficiency (CVI) in people with dark skin tones. It will inform future interventions and modifications to practice for the assessment of CVI in people…
- Conditions
- Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher, Chronic Venous Disease of Lower Limbs, Venous Leg Ulcer (VLU)
- Trial name
- NCT06798766
- Where
- 2 sites in United Kingdom
- Volunteers
- 51 people
- Sponsor
- King's College London
Moderatley to Highly Exuding Venous Leg Ulcers
Evaluate the Impact of Drawtex in Venous Leg Ulcers
This is a clinical study to comparatively evaluate the impact of Drawtex wound dressing against wound bioburden in moderately to highly exuding venous leg ulcers.
- Trial name
- NCT01319123
- Testing
- Drawtex dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Southwest Regional Wound Care Center
Leg Ulcer
Research of Prognostic Factors Associated With Healing of Venous Leg Ulcers
This study was undertaken to identify prospectively which clinical venous leg ulcer (VLU) characteristics known as possible prognostic markers, and which sociodemographic and psychologic factors associated with VLU are associated…
- Trial name
- NCT01673412
- Testing
- Psychological tests
- Where
- 35 sites in France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure