Clinical trials: Ulcer Venous
Venous Leg Ulcer
Helium Neon Laser Versus Gallium Arsenide Laser
There will be different effects for different laser wavelengths in treatment of venous ulcer.
- Trial name
- NCT04689620
- Testing
- laser
- Volunteers
- 60 people
- Sponsor
- Mahmoud Awad Ramadan Elkholy
Hard to Heal Wounds, Venous Leg Ulcers
Efficacy and Safety Study of EscharEx to Treat (Debride) Hard to Heal Wounds
The main objective of this study is to assess the safety and the efficacy of EscharEx in preparing the wound's bed in patients with hard to heal venous leg ulcers, diabetic lower extremity ulcers and traumatic/post operative…
- Conditions
- Hard to Heal Wounds, Venous Leg Ulcers, Diabetic Lower Extremity Ulcers, Traumatic/ Post Operative Wounds
- Trial name
- NCT02020746
- Testing
- EscharEx, Gel Vehicle
- Where
- 8 sites in Israel
- Volunteers
- 111 people
- Sponsor
- MediWound Ltd
Varicose Veins, Venous Stasis
DESIVI: Dosing of Electrical Stimulation in Venous Insufficiency
This study is designed to describe the difference in varicose vein outcomes found from using a neuromuscular electrical stimulation device for different amounts of time - Group A (control - no device), Group B (device for 30 mins…
- Conditions
- Varicose Veins, Venous Stasis, Venous Insufficiency
- Trial name
- DESIVI (NCT03850496)
- Testing
- Revitive IX Neuromuscular Stimulation Device
- Volunteers
- 76 people
- Sponsor
- Imperial College London
Venous Leg Ulcer
Safety Study Providing 12 Months Follow-up From First Exposure to HP802-247 in Subjects With Venous Leg Ulcer
This observations safety study is intended for subject who participated in the 802-247-09-029 study with the investigational product HP802-247 for venous leg ulcers and received at least one application of HP802-247 or Vehicle…
- Trial name
- NCT01658618
- Testing
- HP802-247
- Where
- 49 sites in United States, Canada
- Volunteers
- 440 people
- Sponsor
- Healthpoint
Acute and Chronic Wounds, Pressure Ulcers
Clinical Evaluation of the SNaP Wound Care System
The purpose of this study is to assess the efficacy of design improvements of the Spiracur SNaP Wound Care System. This study prospectively evaluates the safety and efficacy of current and new design iterations of components of…
- Conditions
- Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers
- Trial name
- NCT01113658
- Testing
- SNaP Wound Care System
- Where
- 2 sites in United States
- Sponsor
- 3M
Vein Infusion Phlebitis
The Incidence and Risk of Vein Infusion Phlebitis After Intravenous Infusion of Proton Pump Inhibitors
Intermittent or continuous proton pump inhibitor (PPI) therapy are recommended for high-risk bleeding ulcers according to the French Society of Gastroenterology.
- Trial name
- VeinIPP (NCT04658758)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Venous Leg Ulcer
Phase Ⅱ Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Venous Leg
This project adopts a prospective clinical trial study to compare and evaluate the efficacy of local transplantation of human umbilical cord mesenchymal stem cells combined with silver ion dressing and simple silver ion dressing…
- Trial name
- NCT05319106
- Testing
- stem cell preparation combined with silver ion dressing, silver ion dressing
- Where
- China
- Volunteers
- 76 people
- Sponsor
- ShiCang Yu
Venous Ulcer, Allograft
Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration
Does the use of decellularised dermis allograft in addition to compression therapy promote healing in chronic venous leg ulceration compared to compression therapy alone
- Trial name
- DAVE (NCT04021316)
- Testing
- dCELL® Human Dermis (decellularised dermal skin allograft - DCD), Compression bandaging therapy
- Where
- 17 sites in United Kingdom
- Volunteers
- 71 people
- Sponsor
- Imperial College London
Ulcer, Leg Ulcer
Study of VF001-DP in Patients With Chronic Venous Leg Ulcers
The purpose of this study is to determine if VF001-DP improves wound healing in chronic venous leg ulcers compared to standard care only.
- Conditions
- Ulcer, Leg Ulcer, Varicose Ulcer, Pathologic Processes
- Trial name
- NCT02973893
- Testing
- VF001-DP LD, VF001-DP HD
- Where
- 17 sites in United States
- Volunteers
- 156 people
- Sponsor
- Factor Therapeutics Ltd.
Venous Leg Ulcer
Pilot Study Comparing Negative Pressure Dressings to Conventional Dressings
This study is being conducted to determine how the PICO™ Negative Pressure Wound Therapy compares to standard care treatment for venous stasis ulcers, as there is no evidence to date.
- Trial name
- NCT03450616
- Testing
- PICO Negative Pressure Wound Therapy, Compression Dressing
- Where
- United States
- Sponsor
- Northwell Health
Post Thrombotic Syndrome, Deep Vein Thrombosis
Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS)
The investigators plan to perform an exploratory study to investigate the effects of electro-stimulation of the legs on the symptoms and clinical findings of post thrombotic syndrome (PTS), as well as quality of life of patients…
- Conditions
- Post Thrombotic Syndrome, Deep Vein Thrombosis, Venous Stasis Syndrome, Venous Insufficiency
- Trial name
- VeinoPlus (NCT00858130)
- Testing
- VeinOPlus
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of North Carolina, Chapel Hill
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University
Wound Heal, Venous Leg Ulcer
INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone
INNOVEN is a multi-center randomized controlled clinical trial to evaluate the efficacy of porcine placental extracellular matrix (PPECM) and standard of care (SOC) versus SOC alone in the closure of non-healing venous leg ulcers…
- Trial name
- NCT06606210
- Testing
- InnovaMatrix® AC
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ConvaTec Inc.
Pressure Ulcer, Diabetic Foot Ulcer
An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds
An open, non-comparative, multicenter investigation to evaluate the safety and performance of Exufiber Ag+, a gelling fiber silver dressing, when used in medium to high exuding chronic wounds
- Conditions
- Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
- Trial name
- NCT05494450
- Testing
- ExufiberAG+
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Molnlycke Health Care AB
Venous Ulcer of Leg
Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks
investigates the comparative effectiveness of two interventions aimed at promoting the healing of venous leg ulcers-a common chronic condition characterized by impaired venous return and poor wound healing in the lower…
- Trial name
- Ulcer (NCT07763782)
- Testing
- Dose-Response Structured CMP Activation, Active Control
- Where
- Jordan
- Volunteers
- 80 people
- Sponsor
- MTI University
Lower Extremity Chronic Venous Ulcers
Assessment of the Safety and Efficacy of DERMASTREAM™ - ENZYSTREAM™ System for the Treatment of Chronic Venous Ulcers
The study objectives are to evaluate DermastreamTM - EnzystreamTM system safety, tolerability and efficacy, as a potent method for debridement of nonhealing lower extremity chronic venous ulcers patients.
- Trial name
- ENZ-DER-002-IL (NCT00485329)
- Testing
- Papain
- Where
- 3 sites in Israel
- Volunteers
- 48 people
- Sponsor
- EnzySurge
Diabetic Wounds, Venous Stasis Wounds
The Role of Lipoaspirate Injection in the Treatment of Diabetic Lower Extremity Wounds and Venous Stasis Ulcers
A prospective, single blinded randomized clinical study will be performed to determine if the injection of lipoaspirate into diabetic or venous stasis wounds promotes wound healing or wound closure at a faster rate than…
- Trial name
- NCT00815217
- Testing
- injection of lipoaspirate, control
- Where
- United States
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Venous Leg Ulcer, Diabetic Foot Ulcer
A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers
This study will be a multicenter, prospective, open label, one-arm study intended to assess the clinical performance and safety of EX-02 in debridement of lower leg ulcers: Venous Leg Ulcers (VLU) and Diabetic Foot Ulcer (DFU).
- Trial name
- NCT04817228
- Testing
- EscharEx (EX-02 formulation)
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- MediWound Ltd
Crohn Disease, Ulcerative Colitis
SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD Surgery
Aim to determine if aspirin 81 mg orally twice daily is effective and safe as an extended VTE chemoprophylaxis agent after major abdominal surgery for IBD patients.
- Conditions
- Crohn Disease, Ulcerative Colitis, Venous Thromboembolism
- Trial name
- SAVES-IBD (NCT05104229)
- Testing
- Aspirin 81Mg Ec Tab, Standard of Care
- Where
- United States
- Sponsor
- Stefan Holubar MD MS FACS, FASCRS
Aromatherapy
Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement:
The goal of this pilot clinical trial is to learn if inhalation aromatherapy works to reduce anxiety and pain in patients with venous leg ulcers undergoing conservative sharp wound debridement (CSWD).
- Trial name
- NCT07732036
- Testing
- Inhalation Aromatherapy
- Where
- 2 sites in Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore General Hospital