Clinical trials: Ulcerative
Iron Deficiency Anaemia, Inflammatory Bowel Disease
Safety and Efficacy Study of Oral Ferric Iron To Treat Iron Deficiency Anaemia in Quiescent Ulcerative Colitis (AEGIS-1)
The purpose of this study is to determine whether ST10-021, an oral ferric iron preparation, is safe and effective in the treatment of iron deficiency anaemia (IDA) in subjects with non-active ulcerative colitis (UC).
- Conditions
- Iron Deficiency Anaemia, Inflammatory Bowel Disease, Ulcerative Colitis
- Trial name
- AEGIS-1 (NCT01340872)
- Testing
- ST10-021
- Volunteers
- 128 people
- Sponsor
- Shield Therapeutics
Crohn's Disease, Ulcerative Colitis
An Investigational Study to Test Usability of the Electronic Dosing Equipment Medicpen
This is a study of the electronical dosing tool MedicPen and it's qualities with regards to user friendliness and medication compliance.
- Trial name
- NCT00917514
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Medicpen AB
Ulcerative Colitis
Study to Assess Change in Disease Activity of Risankizumab Treatment in Japanese Participants With Moderate to Severe Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).
- Trial name
- RISE UP (NCT07136116)
- Where
- 29 sites in Japan
- Volunteers
- 200 people
- Sponsor
- AbbVie
Ulcer Venous, Ulcer Foot
Efficacy of a New Composition (BU002) for Debridement of Chronic Cutaneous Ulcers
This study is testing a new liquid treatment for people with long-lasting (chronic) wounds, such as venous leg ulcers or diabetic foot ulcers.
- Trial name
- NCT07607106
- Testing
- BU002, Polyhexanide 0.1% and betaine 0.1% gel
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Universidad del Desarrollo
Ulcerative Colitis
The Effect of Fecal Microbiota Transplantation in Ulcerative Colitis
7 patients with active Ulcerative Colitis are treated with 25 multi-donor FMT Capsules daily for 50 days.
- Trial name
- NCT03711006
- Testing
- Fecal Microbiota Transplantation Capsules
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- Alice Højer Christensen
Healthy Volunteer, Rheumatoid Arthritis
Phenomics in Autoimmune and Inflammatory Diseases
The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and…
- Conditions
- Healthy Volunteer, Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus/Antiphospholipid Syndrome
- Trial name
- TRANSIMMUNOM (NCT02466217)
- Testing
- 1: AID groups, 2: Control groups
- Where
- 2 sites in France
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Foot Ulcer, Diabetic
Dynamic Plantar Microvascular Skin Response to Compressive Loads in At-risk Diabetic and Healthy Control: a Pilot Study
The purpose of this pilot study is to compare the dynamic response of microcirculation in the skin on the bottom of the big toe after applying controlled plantar stress in 25 diabetic subjects with a history of foot ulcer and 25…
- Trial name
- ILH (NCT01580917)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Temple University
Venous Leg Ulcer
Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating venous leg ulcers.
- Trial name
- NCT06930768
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Diabetic Ulcer
Treatment of Wounds Utilizing Light
The Qray device is emitting broad light energy that is intended for diabetic ulcer healing. The study is double blinded.
- Trial name
- NCT00634868
- Testing
- Qray light therapy device
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- QRay Ltd.
IHD, Gastro-Intestinal Disorder
Clinical Study Evaluating the Gastroprotective Effect of Carvedilol in Patients With Ischemic Heart Disease on Aspirin Therapy
The aim of this study is to investigate the possible efficacy of Carvedilol as gastroprotective agent against aspirin-induced upper gastro-intestinal complications in patients with ischemic heart disease (IHD).
- Conditions
- IHD, Gastro-Intestinal Disorder, Aspirin Induced Esophageal Ulcer
- Trial name
- NCT05553717
- Testing
- Carvedilol
- Volunteers
- 66 people
- Sponsor
- Tanta University
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Chemotherapy
The Effect of Education Given on Preventing Mouth Ulcers in Women With Breast Cancer
This study aims to evaluate the effect of nursing education provided to women diagnosed with breast cancer undergoing chemotherapy on their quality of life and the severity of oral mucositis (mouth sores).
- Trial name
- NCT07042568
- Testing
- Nursing education aimed at preventing oral mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Trakya University
Diabetes, Neuropathic Foot
A Comparison of Insoles Used to Prevent Neuropathic Diabetic Foot Ulceration
Importance of the topic: Lower extremity amputation is a costly complication of diabetes for both the NHS and the patient. Amputation may be avoided if the preceding foot ulceration can be prevented.
- Trial name
- NCT00999635
- Testing
- Insole
- Where
- 2 sites in United Kingdom
- Volunteers
- 119 people
- Sponsor
- University of Plymouth
Knee Osteoarthritis, Pressure Ulcer
Pressure Ulcers in Knee Replacement Surgery
From the point of view of nursing to know exactly the different risk factors for the onset of pressure ulcers is very important as it allows to accurately orient preventive care interventions.
- Trial name
- peripress (NCT03039153)
- Where
- Italy
- Volunteers
- 565 people
- Sponsor
- Istituto Ortopedico Rizzoli
Colitis, Ulcerative
Mercaptopurine Therapy in Ulcerative Colitis
This project is a double-blind, randomized, placebo-controlled, multicenter trial in the Netherlands. The aim of this study is to investigate the therapeutic efficacy of optimized 6-mercaptopurine (6-MP) in ulcerative colitis…
- Trial name
- OPTIC (NCT02910245)
- Testing
- Mercaptopurine (Purinethol), Mesalamine, Prednisone
- Where
- 12 sites in Netherlands
- Volunteers
- 136 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Diabetic Foot, Chronic Foot Ulcer
Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers
The study will evaluate the efficacy of SynPath™, a synthetic dermal matrix, in the treatment of diabetic foot ulcers in subjects with diabetes mellitus versus Standard of Care treatment.
- Conditions
- Diabetic Foot, Chronic Foot Ulcer, Wound Healing, Foot Ulcer
- Trial name
- DFUs (NCT05506215)
- Testing
- SynPath Acellular Dermal Matrix plus Off-loading Device, Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- PolyNovo Biomaterials Pty Ltd.
Ulcerative Colitis, Crohn Disease
A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative Colitis
Probiotics are live microorganisms that provide health benefits when consumed in sufficient amounts. Traditional probiotics, mainly from the Lactobacillus and Bifidobacterium genera, originate from fermented foods or the human…
- Trial name
- ANEMONE (NCT07724990)
- Testing
- For a bipsies, rectal administration
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Catholic University of the Sacred Heart
Inflammatory Bowel Disease (IBD)
An Online Intervention to Address Barriers to IBD Medication Adherence
Background Inflammatory Bowel Disease (IBD) is a group of lifelong and relapsing inflammatory conditions that usually affect the colon and the small intestine.
- Trial name
- NCT01852097
- Testing
- CBT based online intervention to elicit and address perceptual and practical barriers to taking medication.
- Volunteers
- 240 people
- Sponsor
- University College, London
Inflammatory Bowel Diseases, Crohn Disease
Real Life Remote Monitoring of Mild, Moderate and Severe Infectious Complications in IBD by Patient Reported Assessment
Inflammatory bowel disease (IBD) is a chronic relapsing immune mediated inflammatory disease (IMID) of the gastrointestinal tract. Like all IMIDs (e.g.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, IBD
- Trial name
- NCT04151420
- Testing
- Remote monitoring tool (infections questionnaire) validation
- Where
- 2 sites in Netherlands
- Volunteers
- 584 people
- Sponsor
- Maastricht University Medical Center
Spinal Cord Injuries, Pressure Ulcer
Alternating Pressure Overlay on Weight Bearing Tissue Tolerance in People With Spinal Cord Injury
The purpose of this study is to test if the newly-developed Dabir alternating pressure (AP) overlay could be beneficial to preventing skin damage during daily activities, such as lying in bed.
- Trial name
- NCT03317288
- Testing
- Dabir Air overlay
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Illinois Chicago
Diabetic Foot Ulcer
Preventing Diabetic Foot Ulcers Through Cleaner Feet
Foot complications are among the most serious and costly complications of diabetes. People with diabetes have a 10-fold increased risk for a leg or foot amputation compared to those that do not have diabetes.
- Trial name
- NCT03503370
- Testing
- Chlorhexidine
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- VA Office of Research and Development
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