Clinical trials: Ulcerative
Varicose Ulcer
Negative Pressure Vs. Compression in Venous Ulcers
This study randomises patients with venous leg ulcers, to be managed either using conventional compression bandages or a bridged vacuum assisted closure system under compression.
- Trial name
- NCT03688841
- Testing
- Bridged V.A.C.® with compression therapy, Conventional Compression Therapy
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Western Vascular Institute, Ireland
Diabetic Foot, Contact Allergy
The Prevalence of Contact Allergies for Wound Dressings In Patients With Diabetic Foot Ulcers (PAID Study)
Rationale: Foot ulcers among diabetics are common. The presence of a contact allergy limits the healing process. Contact allergies for wound dressings are common among patients with ulcers caused by venous insufficiency but less…
- Trial name
- PAID (NCT04085705)
- Testing
- PATCH test
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- Rijnstate Hospital
Ulcerative Colitis, Unspecified
Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis
The research aims to evaluate the efficacy and safety of that mesalazine with hydrocortisone sodium succinate for the induction of clinical remission during a 4-week double-blind treatment period in active UC (define as total…
- Trial name
- NCT03110198
- Testing
- Mesalazine, hydrocortisone sodium succinate, Mesalazine with hydrocortisone sodium succinate
- Where
- China
- Volunteers
- 528 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastrointestinal Injury, Gastrointestinal Hemorrhage
Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality
Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality
- Conditions
- Gastrointestinal Injury, Gastrointestinal Hemorrhage, Gastrointestinal Lesions, Gastrointestinal Ulcer
- Trial name
- GESEMM (NCT05226221)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Campus Bio-Medico University
Diabetic Foot Ulcer
A Two-Part, Randomized Study of Dermacyte® Amniotic Wound Care Matrix
This is a multi-center, prospective, two-part, controlled study to determine the percentage of participants with complete ulcer closure of a target DFU at Week 12 following treatment with Dermacyte Matrix or SOC.
- Trial name
- NCT06444906
- Testing
- Dermacyte Matrix, Standard of Care (SOC)
- Volunteers
- 85 people
- Sponsor
- Merakris Therapeutics
Crohn's Disease, Ulcerative Colitis
Decisional Influences and Inflammatory Bowel Disease (IBD) Patients' Medication Use
The primary purpose of this study is to pilot test an instrument that the investigators will develop to assess decision influences on inflammatory bowel disease patients' medication adherence decision-making.
- Trial name
- NCT00968721
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Vanderbilt University
Venous Leg Ulcer
A Study in Patients With Venous Leg Ulcers and Measuring the Effects of Using Geko™ Device
This is a single centre open label study measuring lower limb physiology in patients with venous leg ulcers at the University Hospital of South Manchester.
- Trial name
- NCT02884323
- Testing
- geko™ device
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Firstkind Ltd
Diabetic Foot
The Healing Effects Of Honey and Hydrogel Products On The Diabetic Foot
The Healing effects of Honey and Hydrogel Products on the Diabetic Foot. Abstract: Diabetes mellitus epidemiology is increasing dramatically affecting high numbers of the world's population, one of the highest risk consequences…
- Trial name
- NCT03816618
- Testing
- Medihoney Gel in A Tube, Hydrogel, Fucidin Ointment
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Cyberjaya University College of Medical Sciences
Leg Ulcer, Diabetic Foot Ulcer
Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia
The purpose of this reseach study is to determine Mölnlycke Health Care´s Leia dressing performance properties is fulfilled and that the dressing is safe when used on wound types such as pressure ulcer, leg ulcer, and diabetic…
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer
- Trial name
- NCT01966380
- Testing
- Leia
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Molnlycke Health Care AB
Chronic Leg Ulcer
Efficacy of 50% Nitrous Oxide/50% Oxygen Gas Premix in Chronic Leg Ulcer Debridement
Adequate analgesia in serial chronic leg ulcer debridement can be difficult to achieve. A common analgesia method is the topical administration of local anesthetics directly onto the wound.
- Trial name
- NCT02696460
- Testing
- N2O/O2 analgesia, Lidocaine/Prilocaine analgesia
- Volunteers
- 21 people
- Sponsor
- Venenklinik Bellevue
ULCERATIVE COLITIS
Intensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET
PHASE: IV TYPE OF STUDY: With direct benefit DESCRIPTIVE: multicenter, open-label, uncontrolled trial INCLUSION CRITERIA: Adults with moderate to severe ulcerative colitis who failed corticosteroids and immunosupressive therapy…
- Trial name
- In-TARGET (NCT02425865)
- Testing
- GOLIMUMAB
- Where
- 23 sites in Belgium, France
- Volunteers
- 202 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Gastrointestinal Ulcer (Peptic) or Erosion, Anti-Platelet Therapy
Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABG
The purpose of this study is to compare the efficacy and safety for 12- vs. 1-month of pantoprazole treatment in preventing dual antiplatelet therapy (DAPT)-related upper gastrointestinal mucosal injury after coronary artery…
- Conditions
- Gastrointestinal Ulcer (Peptic) or Erosion, Anti-Platelet Therapy, Coronary Artery Bypass
- Trial name
- DACAB-GI-2 (NCT03908593)
- Testing
- Pantoprazole
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Ruijin Hospital
Gastrointestinal Hemorrhage, Ulcer Hemorrhage
Hemospray in Gastrointestinal Bleeding: A Real-life Multicenter Cohort
This is an observational, retrospective, analytical, and multicenter study conducted at 17 hospitals. Our research aims to assess the effectiveness of Hemospray® in patients with gastrointestinal bleeding in clinical practice.
- Conditions
- Gastrointestinal Hemorrhage, Ulcer Hemorrhage, Tumor Bleeding
- Trial name
- NCT03611504
- Testing
- Hemospray®
- Where
- Spain
- Volunteers
- 261 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Foot Ulcer, Diabetic
Impact of Remote Foot Temperature Monitoring
One of the only evidence-based practices for the prevention of diabetic foot ulcer recurrence is once-daily foot temperature monitoring, which is recommended by multiple clinical practice guidelines for high-risk patients…
- Trial name
- NCT04345016
- Testing
- Once-daily remote foot temperature monitoring
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Kaiser Permanente
Ulcerative Colitis, Colorectal Cancer
Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695184
- Testing
- ICG-NIRF Imaging
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Diabetic Foot Ulcers
Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers
The aim of this trial is to demonstrate the effectiveness of complete wound healing in a prospective, open-label, case-matched cohort trial in which diabetic foot ulcers (DFU) will be treated using AutoloGel and case-matched…
- Trial name
- NCT01816633
- Testing
- AutoloGel
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Cytomedix
Diabetic Foot Ulcer
Human Placental Mesenchymal Stem Cells Treatment on Diabetic Foot Ulcer
This study is designated to: 1. investigate the tolerance and safety of treatment of Human placental mesenchymal stem cells gel on Human diabetic foot ulcer. 2.
- Trial name
- NCT04464213
- Testing
- Single dose experiments, Multi-dose experiments
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Beijing Tongren Hospital
Crohn Disease, Ulcerative Colitis
TARGET Registry A Project of the German Network for Intestinal Diseases in Cooperation With Other Corporate Partners
By capturing possible or known risk factors, it will be possible to recognize connections between these risk factors and the disease, thus obtaining valuable insights into the cause of the disease.
- Conditions
- Crohn Disease, Ulcerative Colitis, Indeterminate Colitis
- Trial name
- TARGET (NCT04031482)
- Testing
- No intervention, only standard care
- Volunteers
- 4,400 people
- Sponsor
- Ced Service GmbH
Patient Positioning, Monitoring, Physiologic
An Assessment of the Zephyr BioPatch and Its Ability to Monitor Patient Position
The primary objective of the study is to examine the effectiveness of the Zephyr BioPatch in measuring position changes of a non-patient subject in a lab setting and to examine the effectiveness of the Zephyr BioPatch in…
- Conditions
- Patient Positioning, Monitoring, Physiologic, Pressure Ulcer
- Trial name
- NCT02548624
- Testing
- Zephyr BioPatch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Diabetic Foot Ulcer
TWB-103 for Treating Lower Limb Ulcers on Patients With DM
Primary Objective: To assess the safety profile of TWB-103 administered to subjects with diabetic lower limb ulcers Secondary Objective: To explore the efficacy of TWB-103 administered to subjects with diabetic lower limb ulcers
- Trial name
- NCT03624023
- Testing
- TWB-103
- Where
- 2 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- Transwell Biotech Co., Ltd.
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