Clinical trials: Ulcerative
Diabetes, Neuropathic Limb
Novel Home Care Device for High-Risk Diabetic Patients
More than half of all lower extremity amputations are in persons with diabetes. These patients suffer from severe, diabetes-induced, peripheral, sensory neuropathy and, thus they frequently do not protect their feet from…
- Conditions
- Diabetes, Neuropathic Limb, Elevated Temperature, Shear Pressure
- Trial name
- TempTouchRM (NCT00500175)
- Testing
- TempTouchRM, Offloading
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Diabetica Solutions Inc.
Ulcerative Colitis
A Phase II Study to Explore the Safety and Activity of Dersalazine in Patients With Mild to Moderate Ulcerative Colitis
The purpose of the study is to obtain a first clinical assessment of the safety of dersalazine sodium in ulcerative colitis patients with mild to moderate disease.
- Trial name
- NCT00808977
- Testing
- Dersalazine sodium, Mesalazine
- Where
- 22 sites in Belgium, Hungary and 2 more
- Volunteers
- 80 people
- Sponsor
- Palau Pharma S.L.U.
Oral Lichen Planus, Oral Lichenoid Mucositis
Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.
Oral lichen planus (OLP) is a common chronic autoimmune disease associated with cell-mediated immunological dysfunction. Symptomatic OLP is painful and complete healing is rare.
- Conditions
- Oral Lichen Planus, Oral Lichenoid Mucositis, Oral Lichenoid Reaction
- Trial name
- NCT03509675
- Testing
- Ibuprofen suspension 5mg/100ml
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Washington
Inflammatory Bowel Diseases, Ulcerative Colitis
IBD and Women's Health Wellness Program
Researchers want to understand if a combination of usual medical care along with a wellness program designed for women with Inflammatory Bowel Disease diagnosis will have an effect on quality of life, stress, and disease activity.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT05172557
- Testing
- Wellness Program, Wellness Coaching
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis
Open Label Study to Assess Safety, PK and Explore Efficacy of OPRX-106 in Patients With Active Mild to Moderate Ulcerative Colitis
This is a proof of concept, randomized, open label, 2-arm study of OPRX-106 in subjects with active mild to moderate ulcerative colitis.
- Trial name
- NCT02768974
- Testing
- OPRX-106
- Where
- 7 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Protalix
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Gastric Ulcers Duodenal Ulcers Caused by Low-dose Aspirin
Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)
The primary objective of this study to examine the long-term safety of rabeprazole 5 mg or 10 mg tablets administered once daily in participants who were confirmed to have no recurrence of gastric or duodenal ulcer by endoscopic…
- Trial name
- NCT01398410
- Testing
- Rabeprazole
- Where
- 50 sites in Japan
- Volunteers
- 405 people
- Sponsor
- Eisai Co., Ltd.
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Inflammatory Bowel Disease
Precision IFX: Using a Dashboard to Individualize Infliximab Dosage
The introduction of infliximab (IFX) and other monoclonal antibodies (MAbs) targeting tumor necrosis factor (TNF) was a major advancement in the management of inflammatory bowel disease (IBD).
- Trial name
- NCT02624037
- Testing
- Individualized Dosage Precision IFX Dashboard
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dyspepsia, Peptic Ulcer Disease
Minimally Invasive Evaluation of Dyspepsia by Combined Magnetically Controlled Capsule Endoscopy and Urea Breath Test: a Pilot Prospective Cohort Study
The combined diagnostic accuracy of MCCE and UBT in Hong Kong patients with uninvestigated dyspepsia between age 35 to 60 years for structural pathology and HP infection is comparable to that of conventional UGI endoscopy with…
- Conditions
- Dyspepsia, Peptic Ulcer Disease, Gastroesophageal Reflux, Ugi Malignancies
- Trial name
- MCUDYSPEPSIA (NCT04918472)
- Testing
- MCCE
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Venous Leg Ulcer
Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers
The purpose of this study is to determine the systemic exposure of Granexin® gel after topical application to human subjects' venous leg ulcers.
- Trial name
- NCT02652572
- Testing
- Granexin
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Xequel Bio, Inc.
Diabetic Foot
Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients
Following a prior observation that a brief structured group educational intervention is effective for the prevention of diabetic foot ulcers in high-risk patients, but that the efficacy decreases over the time, this study is…
- Trial name
- NCT03555656
- Testing
- Repeated intervention, Single session
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Ulcerative Colitis, Familial Adenomatous Polyposis
Ten Versus Fifteen Centimeter Pouch in IPAA Surgery
The aim of this randomized controlled trial is to compare outcome after construction of an ileal (J-shaped) reservoir of 10 versus 15 centimeters in primary ileal pouch-anal anastomosis surgery.
- Trial name
- TESTIMONY (NCT06538402)
- Testing
- 10 cm pouch, 15 cm pouch
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Odense University Hospital
IBD, COVID
Cohort of Patients With Inflammatory Bowel Disease During COVID-19 Pandemic
Multicenter cohort of patients followed for 6 months during the pandemic in France with biocollection of sera and peripheral blood mononuclear cells
- Trial name
- IBD-COVID-19 (NCT04344249)
- Where
- France
- Volunteers
- 1,109 people
- Sponsor
- Nantes University Hospital
Ulcerative Colitis (UC)
Phase 1b Clinical Study in Patients With Active Ulcerative Colitis
Purpose of study is to evaluate the safety, tolerability, pharmacokinetics of TP317 vs. placebo in adults with active ulcerative colitis.
- Trial name
- TP317-301 (NCT07834515)
- Testing
- TP317
- Volunteers
- 24 people
- Sponsor
- Thetis Pharmaceuticals LLC
Diabetic Foot - Telemedical Monitoring, Diabetic
Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes
This randomized controlled experimental study aims to develop and evaluate the effectiveness of a Virtual Reality-Based "Health to My Foot" program designed for individuals with Type II Diabetes Mellitus.
- Conditions
- Diabetic Foot - Telemedical Monitoring, Diabetic, Foot Care, Virtual Reality
- Trial name
- NCT07473050
- Testing
- "Health for My Feet" virtual reality program.
- Volunteers
- 70 people
- Sponsor
- Ege University
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01154374
- Testing
- MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Skingenix, Inc.
Varicose Veins, Veins Diseases
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
This is a one-arm, open label, prospective, single center study to evaluate clinical standardization with Theraclion's Sonovein 2 HIFU device.
- Conditions
- Varicose Veins, Veins Diseases, Varicose Ulcer
- Trial name
- NCT04280679
- Testing
- Sonovein 2
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Theraclion
Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg
Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering
The aim of this work was to compare the efficacy of intravenous (IV) tramadol versus magnesium sulphate added to 100 ml saline for prevention of shivering associated with spinal anesthesia.
- Conditions
- Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg, Hernia
- Trial name
- NCT06612996
- Testing
- Tramadol, Magnesium sulphate, Saline
- Volunteers
- 180 people
- Sponsor
- Al-Azhar University
Diabetes Mellitus Foot Ulcer
Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaFoot)
This is a no-profit, multicentre, national, clinical trial for the prevention of the complications of the diabetic foot in two populations of patients with diabetes mellitus type-2.
- Trial name
- DARE-DiaFoot (NCT07021222)
- Testing
- Full Analysis, Partial Analysis
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
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