Clinical trials: Ulcerative
Pressure Ulcer
Oxandrolone to Heal Pressure Ulcers
This study is designed to determine whether the use of oxandrolone, an anabolic steroid, can heal pressure ulcers in persons with spinal cord injury (SCI).
- Trial name
- NCT00101361
- Testing
- Oxandrolone
- Where
- 16 sites in United States, Puerto Rico
- Volunteers
- 212 people
- Sponsor
- US Department of Veterans Affairs
Diabetic Foot Ulcer
Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
The purpose of this study is to determine whether a weekly application of EpiFix human amniotic membrane is more effective than a biweekly application (every two weeks) in the treatment of diabetic foot ulcers.
- Trial name
- NCT01657474
- Testing
- Weekly application of EpiFix plus standard of care, Biweekly application of EpiFix plus standard of care
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- MiMedx Group, Inc.
Ulcerative Colitis
The Effect of Diet on Disease Activity and Symptoms in Patients With Ulcerative Colitis
The Mediterranean Diet Pattern (MDP) has been shown to have beneficial effects on the intestinal bacteria and the immune system in diseases like cancer and diabetes.
- Trial name
- NCT03053713
- Testing
- Mediterranean diet pattern, Habitual diet (control)
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia
Chronic Lower Leg Ulcer
Autologous Platelet Enriched Gel Versus Metalloproteinase Inhibitor in the Healing of Chronic Lower Leg Ulcers
Compare Autologous Platelet Enriched Gel versus Metalloproteinase Inhibitor in the healing of chronic lower leg ulcers.
- Trial name
- NCT00658983
- Testing
- Autologous Platelet Enriched Gel, Metalloproteinase Inhibitor
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- University Hospital, Ghent
Ulcerated Melanomas
Adjuvant PEG Intron in Ulcerated Melanoma
Patients with an ulcerated melanoma with Breslow >1 mm, N0M0 have a significantly higher risk for relapse than patients with a non-ulcerated primary and about a 40-50% chance of developing stage IV disease to which they will…
- Trial name
- NCT01502696
- Testing
- PEG IFN alfa-2b
- Where
- 58 sites in Austria, Belgium and 10 more
- Volunteers
- 1,200 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Inflammatory Bowel Disease, Crohn's Disease
Managing Inflammatory Bowel Disease
Inflammatory Bowel Disease (Crohn's disease and ulcerative colitis) often results in significant life disruption, hospitalization and surgery.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- Managing IBD (NCT00679003)
- Testing
- SLCBT, ES
- Volunteers
- 190 people
- Sponsor
- University of Washington
Negative-Pressure Wound Therapy, Diabetic Foot
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
- Trial name
- NCT05716503
- Testing
- Negative Pressure Wound Therapy (NPWT), Ordinary dressings with antibiotic ointment and gauze
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Diabetic Neuropathies, Painful, Diabetic Foot
Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
The purpose of this research is to assess whether the use of a topical cream with an active ingredient can reduce the amount of foot pain experienced in participants who have been diagnosed with Diabetic Peripheral Neuropathy…
- Conditions
- Diabetic Neuropathies, Painful, Diabetic Foot, Diabetic Peripheral Neuropathy
- Trial name
- NCT07260656
- Testing
- Capsaicin Palmitate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carilion Clinic
Crohn's Disease, Ulcerative Colitis (UC)
Expanded Access to Risankizumab
This is an expanded access program (EAP) for eligible participants with Crohn's Disease (CD). This program is designed to provide access to risankizumab, prior to approval by the local regulatory agency, to patients with the…
- Trial name
- NCT03914261
- Testing
- Risankizumab
- Sponsor
- AbbVie
Inflammatory Bowel Disease
Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS)
The investigators are doing the research to discover genes that cause Inflammatory Bowel Disease (IBD) specifically in the African American population.
- Trial name
- MAAIS (NCT01169194)
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Gastrointestinal Hemorrhage
A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer
This study is being carried out to see if constant 3 days infusion of Nexium is effective in preventing rebleeding after an endoscopic treatment.
- Trial name
- NCT00251979
- Testing
- Esomeprazole
- Where
- 78 sites in Austria, Denmark and 14 more
- Volunteers
- 1,312 people
- Sponsor
- AstraZeneca
Duodenal Ulcer Due to Helicobacter Pylori
The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers
Helicobacter pylori (Hp) infection is one of the important causes of gastrointestinal diseases, including gastritis, peptic ulcer, and malignancies, nd the eradication of Hp can effectively cure or prevent these diseases.
- Trial name
- NCT03342456
- Testing
- Doxycycline Hyclate Enteric-Coated Capsules, Amoxicillin Capsules, Ilaprazole Enteric-Coated Tablets
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Inflammatory Bowel Diseases
Effects of Prednisolone and Infliximab on the Regulation of Urea Synthesis in Active Inflammatory Bowel Disease
Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with active inflammatory bowel disease (IBD).
- Trial name
- NCT00955123
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Ulcerative Colitis
A Post-Marketing Surveillance Study to Assess Safety of Ozanimod in Patients With Moderate to Severe Active UC in Korea
The purpose of this observational study is to assess the real-world safety of ozanimod in Korean participants with moderate to severe active ulcerative colitis.
- Trial name
- NCT06073873
- Testing
- Ozanimod
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Bristol-Myers Squibb
Inflammatory Bowel Diseases, Crohn's Disease
The Effect of Joint Transition Visits on Quality of Life in Inflammatory Bowel Diseases (TRANS-IBD)
Inflammatory bowel diseases (IBD) are among the most common chronic illnesses diagnosed in childhood. Moving from the pediatric to the adult health care is a crucial phase, which can greatly affect adolescents' quality of life.
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis
- Trial name
- TRANS-IBD (NCT04290156)
- Testing
- joint visits
- Volunteers
- 160 people
- Sponsor
- University of Pecs
Platelet-rich Fibrin, Macular Holes
Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases
The goal of this clinical trial is to observe the role of PRF in treating ophthalmic diseases.The efficacy and safety of PRF were validated for four ophthalmic conditions: macular hole, pterygium, corneal ulcer, and patients…
- Conditions
- Platelet-rich Fibrin, Macular Holes, Pterygium, Glaucoma
- Trial name
- NCT06200727
- Testing
- PRF membrane tamponade surgery in macular hole, ILM peeling in macular hole, PRF membrane grafting in pterygium
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Lei Du
Ulcerative Colitis
Special Drug-Use Surveillance Study on Vedolizumab for IV Infusion 300 mg [Ulcerative Colitis]
The purpose of this survey is to evaluate the long-term safety and effectiveness of vedolizumab for intravenous (IV) infusion 300 milligrams (mg) in ulcerative colitis (UC) patients in the routine clinical setting.
- Trial name
- NCT03824561
- Testing
- Vedolizumab
- Where
- Japan
- Volunteers
- 1,110 people
- Sponsor
- Takeda
Diabetic Foot - Telemedical Monitoring
The Role of Telemedical Monitoring in Diabetic Foot Ulcer Care
The role of telemedical monitoring in diabetic foot care is still uncertain. The aim is to compare telemedical + standard and standard alone outpatient monitoring in the care of patients with diabetic foot ulcers in a randomized…
- Trial name
- A15-06 (NCT02818322)
- Testing
- telemedical monitoring ( T), classic monitoring
- Where
- France
- Volunteers
- 150 people
- Sponsor
- CHU de Reims
Diabetic Foot
Comparing the Expected Benefit of Extra-corporeal-shockwave Therapy (ESWT) Treatment to Standard Care in Treating Diabetic Foot Ulcers
The purpose of this study is to determine if Extra-corporeal-shockwave Therapy (ESWT) added to standard of care wound therapy significantly improves time to complete wound healing in diabetic foot wounds.
- Trial name
- NCT01499472
- Testing
- shock wave therapy, dermagold shockwave, standard of care
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
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