Clinical trials: Ultrasonic Diagnosis
Endometrial Cancer, Uterine Cancer
Radiomics and Molecular Classification in Endometrial Cancer
Molecular/genomic profiling is the most accurate method to assess the prognosis of endometrial cancer patients. Interestingly, the adoption of radiomics showed important results, across various oncologic specialties.
- Conditions
- Endometrial Cancer, Uterine Cancer, Endometrium Tumor
- Trial name
- ROME (NCT06963385)
- Testing
- Radiomics
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Fetal Volvulus, Midgut Volvulus
Prenatal Diagnosis of Antenatal Midgut Volvulus: Specific Ultrasound Features
Objective: The small bowel volvulus is a rare cause of intestinal obstruction which may occur in utero and whose prenatal diagnosis is difficult.Sonographic signs are mainly indirect and non specific.The aim of this study is to…
- Trial name
- NCT03362450
- Testing
- Fetal ultrasound during the second or third trimester/ Postnatal surgery / Post mortem examination
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Basal Ganglia Hemorrhage
Minimally Invasive Treatment of Hypertensive Basal Ganglia Hemorrhage by Transfrontal Keyhole Neuroendoscopy
To compare the prognosis of patients with hypertensive intracerebral hemorrhage treated by two different surgical methods, and to clarify the therapeutic effect of minimally invasive surgery, so as to find a better surgical…
- Trial name
- NCT04958525
- Testing
- Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal, Small bone window craniotomy for hematoma removal under microscope
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking University Third Hospital
Pulmonary Arterial Hypertension
TReatment Of Pulmonary HYpertension 1-US Study
The objective of this study is to assess the safety, performance and initial effectiveness of the TIVUS™ System when used for pulmonary artery denervation through subjective and objective change in clinical parameters and…
- Trial name
- TROPHY 1-US (NCT02835950)
- Testing
- Therapeutic Intra-Vascular UltraSound (TIVUS™) System
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- SoniVie Inc.
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
Assessment of Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Disorders of Consciousness
The main questions this study aims to answer are: Can low-intensity FUS neuromodulation be safely and feasibly administered to the bilateral central thalamus in patients with disorders of consciousness (DoC)? Does FUS…
- Trial name
- NCT07694258
- Testing
- Next Generation Dome Helmet (NGDH)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Cancer, Prostate Adenocarcinoma
Prospective Comparison of the Four Biopsy Methods for Prostate Cancer Detection
The aim of this study is to compare clinically significant prostate cancer detection rate by the 4 biopsy methods: TRUS-guided, cognitive, fusion and transperineal template mapping biopsy.
- Trial name
- NCT05589558
- Testing
- consequently performed 4 biopsy methods (TRUS-guided biopsy, cognitive, fusion and transperineal template mapping biopsy)
- Where
- Russia
- Volunteers
- 102 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Hip Osteoarthritis
Comparison of the Effect of Intra Articular Steroid Injection and Pericapsular Nerve Group Block for Hip Osteoarthritis
The most common cause of hip joint dysfunction in the elderly is degenerative osteoarthritis of the hip. Innervation of the hip joint capsule is provided by the obturator nerve, the accessory obturator nerve, and the femoral…
- Trial name
- NCT05136248
- Testing
- intraarticular injection, peng block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Transthyretin (TTR) Amyloid Cardiomyopathy
An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.
This is a multi-center, observational study with the overall objective to examine the scale of under-diagnosis for transthyretin amyloid cardiomyopathy (ATTR-CM) across a broad range of diverse health systems in the US using a…
- Trial name
- TRACE Network (NCT07062848)
- Testing
- AI Toolkit for ATTR-CM Diagnosis
- Where
- 12 sites in United States
- Volunteers
- 1,500,000 people
- Sponsor
- Yale University
Sedoanalgesia
Effects of Preoperative Anxiety and Pain Sensitivity in Cases of Endoscopic Ultrasonography Received Sedoanalgesia
The objective of this study was to detect whether preoperative anxiety and pain sensitivity had effects on the consumption of anesthetics, time to achieve desired level of sedation, patient and endoscopist satisfaction, and…
- Trial name
- NCT03114735
- Volunteers
- 80 people
- Sponsor
- Istanbul Medeniyet University
Hemiplegia
Rotator Cuff Tears in Hemiplegic Shoulder
The purpose of the study is to evaluate the prevalence of rotator cuff tears in the shoulders of hemiplegic patients of different severity.
- Trial name
- NCT00998868
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Giant Cell Arteritis (GCA)
oPtic Nerve Sheath Evaluation in gianT Cell aRtheritis by UltraSound
The purpose of this study is to evaluate whether the measure of the optic nerve sheath is a reliable diagnostic marker for giant cell arteritis
- Trial name
- PETRUS (NCT07001059)
- Testing
- orbital ultrasound
- Where
- 9 sites in France
- Volunteers
- 190 people
- Sponsor
- Hôpital NOVO
Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Al Prediction of Sarcopenia Risk in Neurocritical ICU Patients
This prospective observational study aims to evaluate sarcopenia in intensive care patients with intracranial pathologies using ultrasound and to compare the predictive performance of different artificial intelligence models.
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, Epidural Hematoma
- Trial name
- NCT07712198
- Testing
- Prospective Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Breast Cancer
3-Dimensional Form and Soft Tissue Biomechanics of the Breast
The goal of this clinical research study is to characterize the 3-dimensional form and mechanical properties of the breast. Researchers want to do this in order to develop new high technology tools for improving the diagnosis and…
- Trial name
- NCT00502814
- Testing
- 3-D Optical Surface Scan, Mechanical Testing, Cutaneous Ultrasound
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Sickle Cell Disease
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease
This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to < 15 years old, with Sickle Cell Disease.
- Trial name
- HOPE Kids 2 (NCT04218084)
- Testing
- Voxelotor
- Where
- 35 sites in United States, Egypt and 7 more
- Volunteers
- 236 people
- Sponsor
- Pfizer
Mild Hemophilia
Ultrasound Assessment of Joint Health in Patients With Mild Hemophilia (Factor Levels 5-40%)
Currently, few recommendations exist for patients with mild hemophilia, who represent approximately 60% of the hemophilia population.
- Trial name
- echoSAHM (NCT07719647)
- Testing
- Joint Ultrasound (HEAD-US), Blood Sample for Coagulation Factor Measurement
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Super-Resolution Ultrasound Imaging for Assessing Response to Neoadjuvant Chemotherapy in Breast Cancer
1. Study Design Overview Study Type: Single-center, prospective, observational, diagnostic study. Primary Objective: To validate whether Super-Resolution Ultrasound Imaging (SRUS) can accurately predict pathological complete…
- Trial name
- NCT07623226
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Anhui Provincial Cancer Hospital
Dry Needling Lumbar Paraspinal Muscles
Blind Needling Accuracy in Lumbar Muscles
The aim of this study is to evaluate the accuracy of blinded invasive interventions (dry needling) on the deep paraspinal muscles of the lumbar region (iliocostalis lumborum, longissimus thoracis, and multifidus) to reach the…
- Trial name
- NCT07074249
- Testing
- "Anatomical Accuracy of Blind Dry Needling Procedures on the Lumbar Paraspinal Muscles: An Ultrasonography-Assisted Observational Study"
- Volunteers
- 20 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Depression, Anxiety
Focused Ultrasound for Behavioral Health
This is a double-blind, within-participant crossover, multi-site dose-finding study evaluating the safety, feasibility, and preliminary efficacy of repeated low-intensity focused ultrasound (LIFU) stimulation using the ATTN201…
- Conditions
- Depression, Anxiety, Obsessive Compulsive Disorder (OCD)
- Trial name
- VANTUS (NCT07851038)
- Testing
- ATTN201 head-worn focused ultrasound
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Attune Neurosciences Inc
Breast Neoplasms
Ultrasound Targeting for the Lumpectomy Cavity
Accurate targeting of treatment sites should increase local control by radiation therapy for breast-cancer lumpectomy patients. Currently, ultrasound localization is used for prostate cancer patients to locate the prostate before…
- Trial name
- NCT00583843
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Iowa
Renal Diseases, Cerebral Disorder
New Advanced Vascular Imaging Ultrasound Protocols
This is a single-center observational study aimed at setting up and testing new ultrasound vascular imaging protocols, conducted exclusively for research purposes. The study will perform US examinations in 60 subjects.
- Trial name
- RESONA-SETTING (NCT06841887)
- Testing
- US acquisitions
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
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