Clinical trials: Ultrasonography, Doppler
Rheumatoid Arthritis
Impact of the Persistence of Inflammation at Doppler Ultrasound Level on the Structural Evolution of Erosion in Rheumatoid Arthritis Treated With Biotherapy
Since biological disease-modifying anti-rheumatic drugs (bDMARDs) are available in rheumatoid arthritis (RA) strategy an emerging question is the definition of remission in RA.
- Trial name
- NCT02531061
- Testing
- HR-pQCT
- Where
- 2 sites in France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Brain Tumor, Brain Lesion
Intraoperative Functional Ultrasound
A wide spectrum of methods is used to image brain activation in vivo. It can be directly detected by neurons electrical activity imaging (cortical simulation mapping, calcium imaging, voltage sensitive dyes) or indirectly by…
- Trial name
- FUSIMAGINE (NCT02656407)
- Testing
- Ultrasound device
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Graves' Disease
Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves' Disease
All cases of the study will be diagnosed as Graves' by History, examination, laboratory (FT3, FT4, TSH \& TRAbs), X-ray on left wrist for bone age, neck grey scale ultrasonography for thyroid gland size, shape, echotexture…
- Trial name
- NCT06357494
- Volunteers
- 32 people
- Sponsor
- Assiut University
Varicose Veins of Lower Limb, Hemorrhoids
HEMOVAR Study on Hemorrhoids and Varicose Veins
The HEMOVAR Study is a prospective observational study designed to evaluate the association between hemorrhoidal disease and lower extremity varicose veins.
- Trial name
- HEMOVAR (NCT07317492)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Aydin Adnan Menderes University
Psoriasis (PsO), Enthesitis
A Prospective Study to Assess the Efficacy of IL-17 Inhibitors on Subclinical Enthesitis in Patients With Moderate to Severe Psoriasis Based on Power Doppler (PD) Ultrasonography (PDUS)
It is an observational, single-center, prospective, exploratory, open-label study to assess the efficacy and safety of IL-17 inhibitors on subclinical enthesitis in patients with moderate to severe psoriasis with subclinical…
- Conditions
- Psoriasis (PsO), Enthesitis, Psoriasis Arthritis, Secukinumab
- Trial name
- NCT06987292
- Testing
- IL-17i
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Reversible Cerebrovascular Vasoconstriction Syndrome
Retinal Patterns in Reversible Cerebral Vasoconstriction Syndrome
Reversible cerebral vasoconstriction syndrome (RCVS) is a clinico radiological entity characterized by severe headaches (associated or not with neurological complications) during one to 3 weeks, associated with a characteristic…
- Trial name
- SVC-2R (NCT03204110)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Ischemic Stroke
Transcranial Ultrasound in Clinical SONothrombolysis
This is a randomized, placebo controlled, parallel group dose escalation trial to evaluate the safety, tolerability, and activity of four sequential dose tiers of MRX-801 and ultrasound as an adjunctive therapy to tissue…
- Trial name
- TUCSON (NCT00504842)
- Testing
- MRX-801
- Where
- 14 sites in United States, France
- Volunteers
- 72 people
- Sponsor
- ImaRx Therapeutics
Anemia, Endometrial Diseases
Proliferative Effects of Erythropoietin on Human Endometrium
The purpose of this study to assess the proliferative effects of erythropoetin on human endometrium tissue by measuring the endometrial thickness, uterine artery and subendometrial blood flow in postmenopausal women.
- Trial name
- NCT03060603
- Testing
- Erythropoietin
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Deep Vein Thrombosis
Diagnosis Exclusion of Recurrent Deep Vein Thrombosis of the Lower Limbs
The purpose is to assess the safety of a management strategy based on colour doppler ultrasound (CDUS) and D-Dimer test results for the diagnosis exclusion of recurrent deep vein thrombosis (DVT) of the lower limbs.
- Trial name
- ULTREC (NCT03868956)
- Testing
- Colour doppler ultrasound with or without D-dimer test
- Where
- 45 sites in France
- Volunteers
- 466 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Stroke
Prognostic Value of Transcranial Doppler Ultrasound in the Clinical Evolution of Patients With Acute Ischemic Stroke. The TRADE-AIS Study
This prospective observational study aims to determine whether specific parameters measured by transcranial Doppler ultrasound (TCD) can predict clinical outcomes in patients with acute ischemic stroke (AIS).
- Trial name
- TRADE-AIS (NCT07004790)
- Testing
- Transcranial Doppler Ultrasound
- Volunteers
- 50 people
- Sponsor
- Jose Ivan Rodriguez de Molina Serrano
Premature Birth
Cerebral Blood Flow Parameters and Neurobehavioral Development in Infants at Term Age
Although several studies have contrasted the hemodynamics of cerebral arteries using cranial Doppler ultrasound between full-term and preterm infants, the assessments were mostly conducted in the first days of life.
- Trial name
- NCT00676247
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Doppler-Based Renal Ultrasound, Urinary Oxygen Tension
The Predictive Value of Doppler Based Renal Ultrasound and Urinary Oxygen Tension for Prediction of Acute Kidney Injury After Open Heart Surgery
This study aims to investigate the predictive value of Doppler-based renal ultrasound and urinary oxygen tension in the development of acute kidney injury after cardiac surgery.
- Conditions
- Doppler-Based Renal Ultrasound, Urinary Oxygen Tension, Acute Kidney Injury, Open Heart Surgery
- Trial name
- NCT07037485
- Testing
- Renal resistive index, Renal Artery Pulsatility Index, Urinary oxygen tension (PUO2)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Primary Prevention
Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis
Subclinical atherosclerosis is the atherosclerotic process identified before clinical symptoms and thus it can be a useful marker of future cardiovascular events. It can be evaluated by many methods.
- Trial name
- NCT02487615
- Where
- 2 sites in Brazil
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Internal Carotid Artery Stenosis
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy
SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or…
- Trial name
- SONOBIRDIE (NCT02398734)
- Testing
- sonolysis
- Where
- Czechia
- Volunteers
- 1,492 people
- Sponsor
- University Hospital Ostrava
Psoriatic Arthritis, Secukinumab
Prospective Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)
Psoriatic arthritis (PsA) is a complex inflammatory disease with heterogeneous clinical features, which complicates psoriasis in 30% of patients.
- Conditions
- Psoriatic Arthritis, Secukinumab, Ultrasonography
- Trial name
- NCT06730334
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Nanjing Medical University
Recurrent Miscarriage
Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages
The purpose of this study is to determine whether sildenafil citrate is effective in improving uterine artery blood flow and oxidative stress in patients with unexplained recurrent miscarriages
- Trial name
- NCT01419392
- Testing
- Sildenafil citrate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Flow Time, Carotid Doppler Ultrasound
Carotis cFT In Prediction Of Hypotension
The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between…
- Conditions
- Flow Time, Carotid Doppler Ultrasound, Hypotension, Anesthesia
- Trial name
- NCT05896514
- Testing
- ultrasound-guided carotid artery flow time measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Aortic Diseases, Cardiac Surgical Procedures
Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery
In ascending aortic surgery the distal anastomosis may be constructed with the aortic cross-clamp maintained, or, where the extent of the aortic pathology and the geometry of the graft require it, after release of the cross-clamp…
- Conditions
- Aortic Diseases, Cardiac Surgical Procedures, Aortic Aneurysm, Thoracic, Delirium - Postoperative
- Trial name
- SACP-ONSD (NCT07800806)
- Testing
- Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Postmenopausal Bleeding
Three-dimensional Power Doppler in the Diagnosis of Endometrial Lesions in Patients With Postmenopausal Bleeding
100 women suffering post-menopausal bleeding will be included in the study. All the participants will undergo 3D Transvaginal Ultrasound to assess the endometrium and myometrium (for the presence of any focal lesions e.g.
- Trial name
- NCT03543592
- Testing
- 3 dimensional ultrasonography and Doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Hypotension After Spinal Anesthesia
Carotid Ultrasound for Post-Spinal Anesthesia Hypotension in Elderly Hip Surgery
This study aims to evaluate the predictability of preoperative carotid artery-corrected flow time (CFTc) for hypotension after spinal anesthesia in patients undergoing geriatric hip replacement surgery.
- Trial name
- NCT07876063
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University