Clinical trials: Ultrasound Therapy
CLASS II DIVISION 1 MALOCCLUSION
Pain and Comfort During Functional Orthodontic Treatment With Laser or Ultrasounic Waves
Pain, discomfort, and functional limitations are common during functional orthodontic treatment and may affect appliance acceptance, compliance, and treatment satisfaction.
- Trial name
- NCT07852559
- Testing
- Activator + LIPUS, Activator + LLLT
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Cardiorenal Syndrome, Acute Kidney Injury
Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1
During cardiorenal syndrome type 1 (CRS1) vascular congestion is the major contributor to worsening renal function, but promoting decongestion with routine clinical evaluation is ineffective in some patients.
- Conditions
- Cardiorenal Syndrome, Acute Kidney Injury, Decompensated Heart Failure, Fluid Overload
- Trial name
- NCT05927285
- Testing
- Vexus, Control group
- Where
- Mexico
- Volunteers
- 140 people
- Sponsor
- Hospital Civil de Guadalajara
Liver Cancer, HIFU
Symptomatic Abdominal Tumors Are Unsuitable for Surgical Resection, High-intensity Focused Ultrasound (HIFU) Treatment Will be Applied to the Tumors. Postoperatively, Continuous Evaluation and Analysis of the Ablation Effect Will be Performed Using CT or MRI Imaging.
Solid tumors may cause symptoms such as pain due to compression or space-occupying effects. For patients unsuitable for surgical resection, the primary clinical recommendation for malignant tumors is chemotherapy or local…
- Trial name
- NCT07207343
- Testing
- Haifu Focused Ultrasound tumor therapeutic System
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- National Taiwan University Hospital
Locally Advanced Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma
Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
This phase I/II trial studies the effect of sonoporation in addition to standard of care chemotherapy in treating patients with pancreatic cancer.
- Conditions
- Locally Advanced Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8, Stage IIA Pancreatic Cancer AJCC v8
- Trial name
- NCT04821284
- Testing
- Gemcitabine Hydrochloride, Nab-paclitaxel, Fluorouracil
- Where
- 2 sites in United States, Norway
- Volunteers
- 120 people
- Sponsor
- Flemming Forsberg
Speech Disorders
Visual Feedback of Tongue by Ultrasound Echography for Speech Trouble Rehabilitation
Speech is a privileged means of communication for humans: its trouble can thus prove being extremely handicapping. Standard speech therapy is limited in some cases by the lack of sensory feedback available to the patient…
- Trial name
- REVISON (NCT02752425)
- Testing
- Visual feedback
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Acute Myocardial Infarction, Unstable Angina
Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease
Preclinical studies have demonstrated that high mechanical index (MI) impulses from a diagnostic ultrasound (DUS) transducer during an intravenous microbubble infusion (sonothrombolysis) can restore epicardial and microvascular…
- Trial name
- HUBBLE-I (NCT04732091)
- Testing
- Therapeutic ultrasound with 20 usec
- Where
- 2 sites in United States, Brazil
- Volunteers
- 540 people
- Sponsor
- University of Sao Paulo General Hospital
Prostate Hyperplasia
BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY
This is a pilot study on applying 3D-Ultrasound-Guided Transperineal Microwave needle ablation for men with symptomatic benign prostatic hyperplasia (BPH).
- Trial name
- NCT05443451
- Testing
- 3D-Ultrasound-Guided Transperineal Microwave needle ablation of BPH
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- Chinese University of Hong Kong
Breast Fibroadenoma
Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)
This is a monocenter, open-label, uncontrolled study in accordance with §23b MPG to evaluate the efficacy of the HIFU-treatment of fibroadenoma using the TH-One device.
- Trial name
- HIFU (NCT03022695)
- Testing
- High Intensity Focused Ultrasound
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University Hospital Tuebingen
Uterine Fibroids
MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids
This is a prospective, nonrandomized, multi-center study to evaluate the safety and effectiveness of ExAblate in the treatment of uterine fibroids.
- Trial name
- NCT00166270
- Testing
- ExAblate 2000
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- InSightec
Adenomyosis
High-intensity Focused Ultrasound in Treatment of Uterine Adenomyosis
Uterine adenomyosis is a common uterine benign condition. They can cause abnormal menstrual bleeding, and menstrual pain. Although surgical intervention is the definitive treatment, some women prefer to have their uterus…
- Trial name
- NCT02954757
- Testing
- HIFU treatment
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Glioblastoma, Glioma
Safety of BBB Opening With the SonoCloud
PURPOSE: The purpose of this study is to determine whether transient opening of the blood-brain barrier by pulsed ultrasound using the SonoCloud implantable ultrasound device is safely tolerated in patients with recurrent…
- Conditions
- Glioblastoma, Glioma, Brain Tumor
- Trial name
- SONOCLOUD (NCT02253212)
- Testing
- SonoCloud, Carboplatin
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fluid Therapy, Cardiac Surgical Procedures
Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients
The goal of this study is to evaluate whether measures of the size of the internal jugular vein have clinical utility in predicting whether patients may benefit from treatment with intravenous fluid.
- Trial name
- NCT00500981
- Testing
- Volume challenge, Ultrasound evaluation of internal jugular vein
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Achilles Tendinopathy
Evaluation of the Course and Effectiveness of Conservative Therapy in Patients With Achilles Tendinopathy
This work is designed as a randomized clinical trial, in which the effects of a protocol of 12-week resistance training loading the Achilles tendon and low-energy focused extracorporeal shock wave therapy (ESWT) in patients with…
- Trial name
- NCT05702918
- Testing
- BTL-6000 FSWT, Achilles Tendon Loading Exercise Protocol According to Silbernagel
- Where
- Czechia
- Volunteers
- 47 people
- Sponsor
- University Hospital, Motol
Neutropenic Enterocolitis
Bed-side Ultrasound in Neutropenic Enterocolitis
Neutropenic enterocolitis (NEC) is a life-threatening complication of leukemic and solid tumors patients (pts) treated with chemotherapy (CHT) with high mortality rate up to 50-100%. Perforation occurs in 5%-10% of cases.
- Trial name
- NCT04813679
- Testing
- Bed side Ultrasound Sonography
- Where
- Italy
- Volunteers
- 1,740 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Fallopian Obstruction Tube
Ultrasound Guided Fallopian Tube Catheterization During Hysterosalpingo-foam Sonography (HyFoSy)
Investigate a novel ultrasound guided transcervical fallopian tube catheterization during hysterosalpingo-foam sonography in the treatment of proximal tubal obstruction.
- Trial name
- HyFoSy (NCT05537805)
- Testing
- Ultrasound guided transcervical fallopian tube catheterization during hysterosalpingo-foam sonography in the treatment of proximal tubal obstruction
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Plantar Fascitis
Ultrasound Treatment in the Management of Plantar Fasciitis
The purpose of this study is to examine the effectiveness of ultrasound treatment in addition to an exercise program to improve pain and function in individuals with plantar fasciitis.
- Trial name
- NCT04204824
- Testing
- Ultrasound and exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Sage Colleges
Diabetic Foot Ulcer
Ultrasound Assisted Wound Debridement (UAW) Versus Standard Wound Treatment in Complicated Diabetic Foot Ulcers (DFU)
The investigators aimed to elucidate the effects of UAW debridement on cellular proliferation and dermal repair in complicated diabetic foot ulcers as compared to diabetic foot ulcers receiving surgical/sharp wound debridement.
- Trial name
- NCT04633642
- Testing
- Ultrasound group, Surgical group
- Where
- 2 sites in Spain
- Volunteers
- 51 people
- Sponsor
- Universidad Complutense de Madrid
Acute Coronary Syndrome
MDCO-216 Infusions Leading to Changes in Atherosclerosis: A Novel Therapy in Development to Improve Cardiovascular Outcomes - Proof of Concept Intravascular Ultrasound (IVUS), Lipids, and Other Surrogate Biomarkers Trial
This study will be a proof-of-concept, placebo-controlled, double-blind, randomized trial in participants with a recent acute coronary syndrome (ACS) to evaluate the efficacy, pharmacokinetics, safety, tolerability, disease…
- Trial name
- PILOT (NCT02678923)
- Testing
- MDCO-216
- Where
- 20 sites in Canada, Czechia and 3 more
- Volunteers
- 126 people
- Sponsor
- The Medicines Company
Abnormalities, Radiation-Induced, Atherosclerosis
Radiation Induced Atherosclerosis in Breast Cancer Patients
Radiation induced accelerated atherosclerosis is a well known entity that occurs in different regions, according to the therapy delivered.It is usually begins to be clinically evident several years after the radiation incident…
- Conditions
- Abnormalities, Radiation-Induced, Atherosclerosis, Breast Cancer
- Trial name
- NCT00388713
- Testing
- carotid intima-media thickening ultrasound
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Hadassah Medical Organization
Localized Prostate Carcinoma, Castration-Naive Prostate Cancer
Neoadjuvant ADT With TULSA in the Treatment of Intermediate Risk Prostate Cancer
Clinical studies have shown that magnetic resonance imaging-guided transurethral ultrasound ablation (TULSA) of the prostate is safe and effective. In the TULSA procedure, prostate tissue is killed by heating with ultrasound.
- Conditions
- Localized Prostate Carcinoma, Castration-Naive Prostate Cancer, Intermediate Risk Prostate Cancer, Prostate Cancer
- Trial name
- NeoADT-TULSA (NCT05917860)
- Testing
- Degarelix, MRI-guided transurethral ultrasound ablation (TULSA)
- Where
- Finland
- Volunteers
- 15 people
- Sponsor
- Turku University Hospital