Clinical trials: Unconscious
Brain Death
Incidence of Complications of Brain Death
The purpose of the study is to describe the incidence of complications in brain death adult organ donors.
- Trial name
- NCT04404972
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Brno University Hospital
Cardiac Arrest, Comatose
Pilot Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients
The purpose of this study is to determine if the Life Recovery Systems Thermosuit(R) System is able to quickly and conveniently cool patients who are comatose after resuscitation from cardiac arrest.
- Trial name
- NCT00384319
- Testing
- ThermoSuit(R) System
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Life Recovery Systems
Minimally Conscious State
Neurological and Physiological Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State
This study aims to explore the impact of Animal Assisted Therapy (AAT) on brain signal complexity in patients with minimally conscious state (MCS) by analyzing electroencephalogram (EEG) entropy.
- Trial name
- EMCS (NCT06931665)
- Testing
- Animal Assisted Occupational Therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 26 people
- Sponsor
- University of Basel
Cardiac Arrest With Successful Resuscitation
Study of Brain Cools Device in Patients Resuscitated From Cardiac Arrest
This submission is a pilot in which the new IQool Warming System device will be used to maintain the temperature of adult patients in cardiac arrest within a range of within a range of 32°C to 38.5°C (89.6°F to 101.3°F).
- Trial name
- NCT03889340
- Testing
- IQool
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Adam Frisch
Vasovagal Syncope (VVS), Presyncope
A Warning Red Flag Classification System to Predict Risk of Vasovagal Event During Office Hysteroscopy
The goal of this pilot cross sectional study is to identify participants at risk of vasovagal reaction/syncope(VVR/VVS) during office hysteroscopy.
- Trial name
- FLAG-VS (NCT07030218)
- Testing
- Office hysteroscopy
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanvir Hospital
Coma, Major Trauma
Succinylcholine vs Rocuronium for Prehospital Emergency Intubation
All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency…
- Conditions
- Coma, Major Trauma, Respiratory Distress, Shock
- Trial name
- CURASMUR (NCT02000674)
- Testing
- Succinylcholine : 1mg/kg, Rocuronium : 1.2 mg/kg
- Where
- 17 sites in France
- Volunteers
- 1,321 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Acquired Brain Injury, Coma
Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot Study
This is a pilot study. The objective is to further understand the mechanism by which amantadine improves function in patients with persistent vegetative state and minimally conscious state.
- Conditions
- Acquired Brain Injury, Coma, Persistent Vegetative State, Minimally Conscious State
- Trial name
- NCT02566720
- Testing
- Amantadine, MRI Tractography Study
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Hamilton Health Sciences Corporation
Hypercapnia, Exercise
Hypercapnia: Cognitive Effects and Monitoring
The investigators will simulate the conditions of a working, helmeted diver by using exercising, "head out" immersed subjects to test the following hypotheses: 1.
- Conditions
- Hypercapnia, Exercise, Nitrogen Narcosis, Diving
- Trial name
- NCT01782625
- Testing
- NO exercise at depth, exercise at depth
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Duke University
Reflex Syncope
Cardioneuroablation in Reflex Syncope (CARDIOSYRE Trial)
Background: Reflex syncope is a disease of benign etiology but in severe cases it can be disabling and it carries a risk of severe trauma.
- Trial name
- CARDIOSYE (NCT05513755)
- Testing
- cardioneuroablation
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Fundación de investigación HM
Syncope, Vasovagal
Treatment Strategy of Vasovagal Syncope
This is a prospective, international multi-center, open-labeled, randomized trial. The investigator speculated that CNA prevents more patients with moderate to severe VVS from syncope recurrence compared to midodrine.
- Trial name
- CAMPAIGN (NCT05803148)
- Testing
- Cardioneuroablation, Midodrine Oral Tablet
- Where
- China
- Volunteers
- 184 people
- Sponsor
- China National Center for Cardiovascular Diseases
Orthostatic Intolerance, Syncope
Lower Body Muscle Pre-activation in Initial Orthostatic Hypotension
This study is aimed primarily at providing a simple and effective form of treatment to reduce the symptoms of Initial Orthostatic Hypotension (IOH) and prevent syncope.
- Conditions
- Orthostatic Intolerance, Syncope, Fainting, Presyncope
- Trial name
- IOH (NCT03970551)
- Testing
- Physical Counter-maneuver, Stress Test, Functional Electrical Stimulation
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Heart Arrest, Out-Of-Hospital, Computed Tomography
Head Computed Tomography for Predicting Neurological Outcome After Cardiac Arrest
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) joint guidelines for post-resuscitation care recommend a multimodal approach to prognostication of neurological outcome.
- Conditions
- Heart Arrest, Out-Of-Hospital, Computed Tomography, Unconsciousness, Neurologic Deficits
- Trial name
- NCT03913065
- Testing
- CT
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Lund University
Pressure Ulcer
Prevention of Pressure Ulcer by Lateral Tilt Bed in Neurocritical Care
Patient positioning is an essential part of a preventive strategy for neurocritical care patients. The aim of the study will be to determine whether the positioning of the bed is the same or better compared to the positioning of…
- Trial name
- PULAT-NC (NCT04078477)
- Testing
- Body positioning
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Regional Hospital Liberec
Syncope
Exercise and Prevention of Syncope: EXPOSE
The purpose of this study is to determine whether eight weeks of exercise performed at an intensity of approximately 65% VO2max will improve symptoms associated with fainting (vasovagal syncope).
- Trial name
- NCT00203593
- Testing
- Exercise, Blood volume, VO2max test
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Syncope, Postural Tachycardia Syndrome
EEG Characteristics in Youth POTS and/or Syncope
Orthostatic intolerance refers to symptoms that occur with standing and improve or resolve with recumbency. Few studies have evaluated orthostatic intolerance symptoms by electroencephalography (EEG), and none of those studies…
- Conditions
- Syncope, Postural Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- NCT02167412
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Nationwide Children's Hospital
Type 1 Diabetes Mellitus
Propranolol in Treating Hypoglycemia Unawareness
Impaired awareness of hypoglycemia is common in type 1 diabetes (T1DM) patients. Impaired hypoglycemia awareness increases severe hypoglycemia risk by six-fold.
- Trial name
- NCT03161964
- Testing
- Propranolol 80 Mg Oral Capsule, Extended Release
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Anu Sharma
Coma
Improving Awakening Prognostication After Non Anoxic Coma Using PET-MRI in Intensive Care Unit
In last decades, several advances in the neuro-intensive management have lead to decrease mortality in Intensive Care Units. A significant morbidity remains as patients survive after a traumatic coma with uncertain quality of…
- Trial name
- ETIC (NCT02798588)
- Testing
- PET-MRI
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Hospices Civils de Lyon
Pulpitis
A Study of the Trigeminal Cardio-Reflex in Endodontic and Other Dental Treatment
This study sought to comprehend the relationship between syncope and dental related therapy. If the relationship between dental related therapies and syncope is proved, clinical dentists will be remained to monitor changes of…
- Trial name
- NCT02745782
- Testing
- Observational Study
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- YI SHENG HUANG
Concussion, Mild, Concussion, Brain
Building Emotional Self-Awareness Teletherapy (BEST)
To examine the feasibility, acceptability, and preliminary efficacy of a remotely delivered intervention for civilians and service members with mild traumatic brain injury (mTBI) who have difficulty recognizing and regulating…
- Conditions
- Concussion, Mild, Concussion, Brain, Concussion, Severe, Concussion, Intermediate
- Trial name
- BEST (NCT05623046)
- Testing
- Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Syncope, Vasovagal
Heart Rate Variation in Females Predicts Tilt Test Results
Head-up tilt test (HUTT) is widely used to evaluate patients with unexplained syncope, but data on clinical predictors of HUTT results are limited.
- Trial name
- NCT06496074
- Testing
- Head-up Tilt Test
- Where
- Brazil
- Volunteers
- 149 people
- Sponsor
- Federal University of Piaui