Clinical trials: Unconscious
Type 1 Diabetes Mellitus
B-Lymphocyte Immunotherapy in Islet Transplantation
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- NCT00468442
- Testing
- Allogeneic Pancreatic Islet Cells, Antithymocyte globulin, Daclizumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 1 Diabetes, Hypoglycemia Unawareness
Hypoglycemia Awareness Study in Diabetes Type 1
The goal of this observational study is to assess clinical factors associated with the occurrence of impaired hypoglycemia awareness in adult patients with type 1 diabetes The main questions it aims to answer are: 1.
- Conditions
- Type 1 Diabetes, Hypoglycemia Unawareness, Cardiac Autonomic Neuropathy
- Trial name
- HAD-1 (NCT05620927)
- Where
- Poland
- Volunteers
- 245 people
- Sponsor
- Poznan University of Medical Sciences
Type 1 Diabetes, Hypoglycemia
Impact of Hypoglycemia Unawareness on Brain Metabolism Cognition in T1DM
The research study is designed to examine the impact of low blood sugar on brain function in individuals with Type 1 Diabetes who have frequent and severe hypoglycemia (low blood sugar) compared to those who do not.
- Trial name
- NCT00575783
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yale University
Bariatric Surgery
Glycemic Patterns After Bariatric Surgery and High Glycemic Variability and Hypoglycemia Unawareness Risk Factors
To study the glycemic patterns of patients undergoing bariatric surgery and what are the risk factors capable of predicting episodes of unnoticed hypoglycemia and high glycemic variability, evaluating patients who underwent…
- Trial name
- NCT05728320
- Testing
- Glucose monitoring with flash glucose monitor
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Clinical Intuition
CLINICAL INTUITION is an Experience-based, Often Unconscious Assessment of a Patient's Resilience and Tolerance. It is INFLUENCED by Clinical Signs, Behavior, Functioning, and Context. While it MAY PREDICT Patient Dropout, it is Difficult to Objectify.
Patient selection for Phase I oncology trials is formally based on protocol-defined inclusion and exclusion criteria. In practice, however, healthcare professionals also take clinical intuition and professional experience into…
- Trial name
- MINC (NCT07877623)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Cardiac Disease, Syncope
Second Study on Cardio-neuromodulation in Humans
Different approaches to cardio-neuroablation (CNA) to treat neurally mediated syncope, sinus node dysfunction, and functional atrioventricular block have been published.
- Conditions
- Cardiac Disease, Syncope, Syncope, Vasovagal, Sick Sinus Syndrome
- Trial name
- CardNMH2 (NCT02954666)
- Testing
- radio-frequency ablation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Imelda Hospital, Bonheiden
Coma, Heart Arrest
Predictive Outcome in Comatose Patients
Evaluating the prognosis of comatose patients after cardiac arrest (CA) in the intensive care unit (ICU) remains challenging. It requires a multimodal approach combining standardized clinical examination, serum biomarkers…
- Conditions
- Coma, Heart Arrest, Cardiopulmonary Resuscitation
- Trial name
- PRECOM (NCT05321459)
- Testing
- Neurological prognosis
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Death, Organ Donation
Donation Network to Optimize Organ Recovery Study
This study consists in an cluster-randomized clinical trial involving near 60 Brazilian intensive care units (ICUs) with a high notification rate of potential donors of organs and tissues.
- Trial name
- DONORS (NCT03179020)
- Testing
- Checklist use, Usual care
- Where
- 63 sites in Brazil
- Volunteers
- 1,535 people
- Sponsor
- Hospital Moinhos de Vento
Atrial Fibrillation, Syncope
LUX-Dx Insertable Cardiac Monitor Remote Programming and Performance Study
The LUX-Dx PERFORM Study had two primary objects which were (1) to characterize, in a general patient population, the utilization of the remote programming feature of the Boston Scientific (BSC) Insertable Cardiac Monitor (ICM)…
- Conditions
- Atrial Fibrillation, Syncope, Cryptogenic Stroke
- Trial name
- LUX-Dx PERFORM (NCT04732728)
- Where
- 24 sites in United States
- Volunteers
- 727 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Symptomatic Neurogenic Orthostatic Hypotension
Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure
A Phase 3 study to evaluate efficacy, safety, and tolerability of ampreloxetine (TD-9855) in subjects with primary autonomic failures (MSA, PD, or PAF) and symptomatic nOH with up to 4 weeks of treatment.
- Trial name
- SEQUOIA (NCT03750552)
- Testing
- ampreloxetine
- Where
- 125 sites in United States, Australia and 17 more
- Volunteers
- 195 people
- Sponsor
- Theravance Biopharma
Epilepsy, Epilepsy, Generalized
Clobazam in Patients With Lennox-Gastaut Syndrome
The purpose of this study is to evaluate the safety and efficacy of clobazam as adjunctive therapy in the treatment of seizures which lead to drop attacks (drop seizures) in patients 2 to 60 years of age with Lennox-Gastaut…
- Conditions
- Epilepsy, Epilepsy, Generalized, Seizures
- Trial name
- NCT00518713
- Testing
- Clobazam Low Dose, Clobazam Medium Dose, Clobazam High Dose
- Where
- 53 sites in United States, Australia and 3 more
- Volunteers
- 238 people
- Sponsor
- Lundbeck LLC
Syncope, Vasovagal
Predictive Factors for Hypotensive Bradycardic Events During Arthroscopic Shoulder Surgery
Patients's demographics and perioperative factors affect the occurrence of hypotensive bradycardic events in the patients undergoing arthroscopic shoulder surgery in the sitting position under interscalene block.
- Trial name
- NCT01926561
- Testing
- Interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center