Clinical trials: Unconsciousness
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage
A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
1. The primary aim of this study is to investigate the correlation between the length of ICU stay and a newly developed FIVE score in neuro-intensive care patients. 2.
- Conditions
- Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage, Supratentorial Cancer, Infratentorial Neoplasms
- Trial name
- NCT06036732
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people
- Sponsor
- Istanbul University - Cerrahpasa
Hypoglycemia Unawareness, Type 1 Diabetes
Glucose Counterregulation in Long Standing Type 1 Diabetes
Enrollment for this study is complete. This study is designed to determine if use of a real-time continuous glucose monitor (RT-CGM) can reverse defective Glucose counter regulation and hypoglycemia unawareness in long standing…
- Conditions
- Hypoglycemia Unawareness, Type 1 Diabetes, Healthy
- Trial name
- NCT01474889
- Testing
- RT-CGM
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Pennsylvania
Unconsciousness, Consciousness
UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study
This study will be a single-site, controlled, unblinded study at the University of Wisconsin to examine changes in the electroencephalogram during anesthesia and waking.
- Trial name
- UN-CONSCIOUS (NCT03284307)
- Testing
- Dexmedetomidine, Ketamine, Propofol
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Syncope, Unconscious State
Management of Transitory Loss of Consciousness and Syncopes in the Emergency Department
The goal of this observational study is to examine the clinical presentations, the diagnostic tests performed and the management of patients presenting with transient loss of consciousness (TLOC) The main questions it aims to…
- Trial name
- NCT05575934
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Clermont-Ferrand
Brain Diseases, Vegetative State
Chinese Validation of the Simplified Evaluation of CONsciousness Disorders（SECONDs）
The aim of this study was to translate the SECONDs from French into Chinese and assess the validity and reliability of the Chinese version of the SECONDs .
- Conditions
- Brain Diseases, Vegetative State, Unconsciousness, Central Nervous System Diseases
- Trial name
- NCT05496985
- Testing
- Simplified Evaluation of CONsciousness Disorders (SECONDs)
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Hangzhou Normal University
Syncope
Pacemaker Effect With Closed Loop Sensor in Neuromodulated Syncope Refractory to Medical Therapy
Vasovagal syncope is an entity frequently in the emergency services, its treatment includes pharmacological and non-pharmacological measures, and in some severe cases, requires the implantation of cardiac stimulation devices…
- Trial name
- NCT03876652
- Testing
- Pacemaker with Closed Loop Stimulation (CLS)
- Where
- 2 sites in Colombia
- Volunteers
- 48 people
- Sponsor
- CES University
Pain, Opioid Use
Nociception-Level (NOL) for the Assessment of Pain in Patient Unable to Self-Report
In this study we aimed to investigate the performance and effectiveness of NOL and/or NOLedge as a tool for pain assessment in geriatric and critical ill non communicating patients.
- Conditions
- Pain, Opioid Use, Dementia, Unconscious
- Trial name
- MoNOLog (NCT04581642)
- Testing
- PMD200
- Where
- Israel
- Volunteers
- 33 people
- Sponsor
- Medasense Biometrics Ltd
Out-Of-Hospital Cardiac Arrest, Emergencies
Livestreaming From Smartphones as a Supplement to Emergency Calls
The aim of the study is to analyse if live video as a supplement to emergency calls can improve medical dispatchers' situation awareness and enhance the assistance they provide including provision of pre-hospital resources.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Emergencies, Unconscious
- Trial name
- NCT04061187
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Loss of Consciousness
Remimazolam Bolus for General Anesthesia
It is important to estimate the adequate dose of remimazolam intravenous bolus injection to induce the loss of consciousness. We will determine the ED50 and ED95 of remimazolam intravenous bolus on the loss of consciousness in…
- Trial name
- NCT04901871
- Testing
- 0.02 mg/kg, age<65, 0.07 mg/kg, age<65, 0.12 mg/kg, age<65
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Electroencephalogram, Consciousness, Loss of
The Electroencephalogram and Clinical Effect of Ketamine
The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain.
- Trial name
- NCT03679390
- Testing
- Ketamine
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Taiwan University Hospital
Syncope, Seizures
Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Syncopation and Seizure
Changes of thyroid function may occur after short loss of consciousness, but they haven't been systematically evaluated up to now, although occasional observations suggest temporal increases in TSH concentration.
- Trial name
- Thyro-Syncope (NCT04879147)
- Testing
- Evalution of thyroid function
- Where
- 4 sites in Germany
- Volunteers
- 350 people
- Sponsor
- Ruhr University of Bochum
Type 1 Diabetes, Hypoglycemia Unawareness
A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes
This is a single center, double blind randomized cross over design trial that will compare the impact of N-acetyl cysteine (200 mg) vs.
- Trial name
- NAC for HAAF (NCT02206152)
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Minnesota
Unconsciousness, Apnea, Postanesthetic
Race-Specific Propofol Titration to Effect for Procedural Sedation
Prospectively evaluate newly established guidelines and make clinicians aware of inter-racial difference in propofol sensitivity.
- Conditions
- Unconsciousness, Apnea, Postanesthetic, Sedative Overdose, Hypoxemia
- Trial name
- NCT03290859
- Testing
- Titrate propofol monotherapy infusion to effect
- Where
- United States
- Volunteers
- 2,780 people
- Sponsor
- University of Florida
Unconscious (Psychology)
Memory Priming in General Anesthesia
Memory priming under general anesthesia is a phenomenon of incredible interest in the study of consciousness and unconscious cognitive processing, and for clinical practice.
- Trial name
- NCT03727464
- Testing
- Abstract priming, Concrete priming, Controls
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Arrhythmia, Hemorrhage
Suitability of Unobtrusive Bed Monitoring and Wrist-worn Heart Rate Monitor for Patient Monitoring
Novel technology enables it to monitor noninvasively the vital signs of a patient. Such a monitoring is immediately required to improve patient safety and to reduce hospital readmissions.
- Conditions
- Arrhythmia, Hemorrhage, Septic Shock, Consciousness, Loss of
- Trial name
- BedMon (NCT03572751)
- Testing
- Bed-, wrist- and ECG-sensor monitoring
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Tampere University Hospital
Unconsciousness
Comparison of Three Methods for NG Tube Placement
Background and Aim: Tubular feeding is used, in patients who cannot take food through their mouths, but the digestive system has the ability to digest food.
- Trial name
- NG (NCT03699306)
- Testing
- NG tube insertion method
- Where
- 2 sites in Iran
- Volunteers
- 75 people
- Sponsor
- Isfahan University of Medical Sciences
Unconscious (Psychology)
Diagnostic Value of Arterial Blood Gas Analysis in Prehospital Patients
In the anesthesiologist-manned mobile emergency car unit an analyzing device for blood gas testing is present since 2014. This study will determine if a prehospital arterial blood gas helps the doctor to make more precise…
- Trial name
- ABL (NCT03006692)
- Testing
- With arterial blood gas, parameters not being normal can be corrected
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Unconscious, Inflammation
Volume Kinetics for 20% Albumin in Different Clinical Situations
The study aims to determine the degree of plasma volume expansion and the half-life of the plasma volume expansion when 3 mL/kg of hyperoncotic (20%) albumin if infused over 30 minutes in conscious healthy volunteers, in patients…
- Trial name
- Albumin (NCT02556580)
- Testing
- Albumin 20%
- Where
- 2 sites in Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
Mounier-Kuhn Syndrome
Airway Collapse in Patients With Mounier-Kuhn Syndrome: Titration With Positive Pressure to Reduce Collapse
Mounier-Kuhn syndrome (MKS), or congenital tracheobronchiomegaly, is an entity characterized by dilation of the trachea and bronchi, associated with respiratory infections.The main signs and symptoms are cough, bulging and…
- Trial name
- NCT03101059
- Testing
- Non invasive ventilation - Continuous Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital