Clinical trials: Unicompartmental Knee Replacement
Osteoarthritis
Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
The objective of this prospective study is to determine (1) the time course of patient-relevant functional outcome evaluated by the Knee injury and Osteoarthritis Outcome Score (KOOS) and (2) the time course of range of motion…
- Trial name
- NCT01032538
- Where
- 3 sites in Norway
- Volunteers
- 99 people
- Sponsor
- Vestre Viken Hospital Trust
Postoperative Pain
Local Infiltration Analgesia Following Unicompartmental Knee Arthroplasty
The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect hospital stay.
- Trial name
- NCT00653926
- Testing
- ropivacaine, ketorelac and epinephrine, saline
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Osteoarthritis
Fixed Bearing Versus Mobile Bearing Patient Satisfaction and Clinical Outcome Study
The purpose of this study is to determine if there is a patient satisfaction preference of Fixed Bearing versus Mobile Bearing Unicompartmental Knee Arthroplasty (UKA) in patients who are at a minimum two years post operative.
- Trial name
- NCT02633085
- Testing
- Fixed Bearing or Mobile Bearing UKA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medacta USA
Knee Osteoarthritis, Hip Osteoarthritis
Daycase Hip and Knee Arthroplasty in Møre and Romsdal Trial
The DART Study is a prospective, multicentre observational cohort study evaluating day-case pathways for patients undergoing primary total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty at three…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Osteonecrosis, Osteoarthritis
- Trial name
- DART (NCT07834034)
- Testing
- Total Hip Arthroplasty, Total Knee Arthroplasty, Unicondylar knee artrhoplasty
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Helse Møre og Romsdal HF
Knee Osteoarthritis
Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial
Unicompartmental knee arthroplasty (UKA) and High Tibial Osteotomy are both valid treatment options for isolated medial knee osteoarthritis.
- Trial name
- UNIKORN (NCT05442242)
- Testing
- Unicompartmental knee arthroplasty, High tibial osteotomy
- Volunteers
- 100 people
- Sponsor
- Töölö Hospital
Osteoarthritis
A Clinical Investigation of the Oxford® Partial Knee System
The purpose of this prospective data collection is to document the performance and clinical outcomes of the Oxford® Partial Knee System.
- Trial name
- NCT00699257
- Volunteers
- 85 people
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthritis, Knee
Oxford Partial Knee Replacement. A Randomized Clinical Trial of Three Implant Types
The purpose of this scientific study is to clarify whether there is a relationship between the appearance of radiolucent lines in bone-cement interphase of the tibial component of the different models of the Oxford Uni Knee…
- Trial name
- NCT00679120
- Testing
- Oxford Uni Knee
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- University of Aarhus
Loosening, Prosthesis
Efficacy of Robot-assisted Technique vs Conventional Technique in Preventing Early Micromobilisation After UKA
The purpose of this study is to compare the percentage of early micromibilisation in unicompartmental knee arthroplasties in robot-assisted technique vs standard technique.
- Trial name
- NCT05204797
- Testing
- Robot-assisted UKA, Standard technique UKA
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteo Arthritis Knee
Cryo and Compression Therapy After TKA and UKA
The goal of this clinical trial is to test the use of a cold and compression brace during the first 6 weeks after surgery in patients who had a total or partial knee replacement.
- Trial name
- NCT05572359
- Testing
- cryo-and compression brace
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- Martini Hospital Groningen
Osteoarthritis
Out Patient Surgery for Total Knee and Hip Replacement and Unicompartmental Knee Replacement - a Feasibility Study
The purpose of this study is to evaluate feasibly of outpatient Total Knee Replacement, Total Hip Replacement and Unicompartmental Knee Replacement in a modern fast-track setup.
- Trial name
- NCT02544620
- Testing
- Does fulfil of discharge criteria on the day of the surgery, Does not fulfil of discharge criteria on the day of the surgery
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Kirill Gromov
Orthostatic Hypotension, Orthostatic Intolerance
Postoperative Incidence of Orthostatic Intolerance and Hypotension in Primary Unicompartmental Knee Arthroplasty (UKA)
Incidence and pathophysiologic hemodynamics of orthostatic intolerance and orthostatic hypotension in patients undergoing UKA
- Conditions
- Orthostatic Hypotension, Orthostatic Intolerance, Postoperative Complications
- Trial name
- NCT04195360
- Testing
- Standardized mobilization procedure
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Knee Osteoarthritis
Oxford UKA and HTO Post-market Clinical Study
The purpose of this study is to compare the performance and safety of medial UKA and HTO in the treatment of AMOA in term of functional outcome, radiographic assessment, range of motion, postoperative complications, revision rate…
- Trial name
- NCT04518111
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Study of Patient Outcomes 5 Years After Partial Knee Replacement
The study seeks to evaluate the condition of patients 5 years after having undergone partial knee replacement for localized osteoarthritis of the knee.
- Trial name
- NCT01620892
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Athens Orthopedic Clinic, P.A.
Total Knee Arthroplasty, Knee Arthroplasty
Risk of Serious Adverse Events Following Unsupervised vs Supervised Rehabilitation After Knee Arthroplasty
SUMMARY Background: After knee arthroplasty (KA), rehabilitation is widely recommended, yet its clinical effectiveness-especially the need for supervision-has been challenged.
- Conditions
- Total Knee Arthroplasty, Knee Arthroplasty, Unicompartmental Knee Arthroplasty
- Trial name
- SAFE-T (NCT07067060)
- Volunteers
- 40,000 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Osteoarthritis, Unicompartmental Knee Arthroplasty
Post-op Prednisone and Glucose Monitoring in TKA
This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels…
- Conditions
- Osteoarthritis, Unicompartmental Knee Arthroplasty, Total Hip Arthroplasty (THA)
- Trial name
- NCT07630896
- Testing
- Prednisone, Continuous Glucose Monitor, InkWell Health Tattoos
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Columbia University
Osteoarthritis, Unicompartmental Knee Arthroscopy
A Single-Center, Epidemiological Study of the Survivorship of the DePuy Sigma HP Unicompartmental Knee Prosthesis
This study will be conducted to assess the survivorship of a particular prosthesis used in unicompartmental knee arthroplasties.
- Trial name
- NCT01656694
- Testing
- DePuy Sigma HP Partial Knee
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mississippi Sports Medicine and Orthopaedic Center
Prosthetic Joint Infection, Unicompartmental Knee Arthroplasty
Metal Artifact Reduction Sequence MRI for Surgical Decision-Making in Infected Unicompartmental Knee Arthroplasty
A single-center retrospective cohort study was conducted in the Department of Orthopedics of Fujian Medical University Affiliated First Hospital.
- Trial name
- NCT07208968
- Where
- China
- Volunteers
- 28 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Knee Osteoarthritis
Comparison of Functional Outcomes of Three Surgical Approaches in Knee Arthroplasty
A functional outcomes comparison study of three surgical techniques using minimally invasive surgery mini-incision (MIS) for total knee arthroplasty (TKA), standard para-patellar TKA and the unicompartmental knee arthroplasty…
- Trial name
- NCT00983762
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Knee Osteoarthritis, Total Knee Arthroplasty
Improved Pain Management in Knee Osteoarthritis-related Surgeries
In recent years, pain management coordinated with enhanced recovery after surgery (ERAS) has been widely applied and rapidly developed in orthopedics, showing promising prospects.
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Unicompartmental Knee Arthroplasty, High Tibial Osteotomy
- Trial name
- NCT06124170
- Testing
- Preoperative pain managment, Intraoperative pain managment, Postoperative pain managment
- Where
- China
- Volunteers
- 714 people
- Sponsor
- Peng Liu
Arthritis, Osteoarthritis
A Comparison of Patients Receiving a Unicompartmental Knee Replacement With Robotic Assistance or With Conventional Instrumentation
A unicompartmental (partial) knee replacement (UKR) is the removal of one part of the knee joint (a condyle), that has become damaged due to osteoarthritis, and replacing it with an artificial implant.
- Conditions
- Arthritis, Osteoarthritis, Knee, Joint Diseases
- Trial name
- NCT04992078
- Testing
- NAVIO/CORI Surgical System, Non-robotic conventional instrumentation
- Where
- 6 sites in Ireland, United Kingdom
- Sponsor
- Smith & Nephew Orthopaedics AG