Clinical trials: Unicompartmental Knee Replacement
Medial Knee Osteoarthritis
Partial vs Total Knee Replacement for Medial Knee Osteoarthritis: a Prospective Randomized Controlled Study
The goal of this clinical trial is to learn whether partial knee replacement (unicompartmental knee arthroplasty, UKA) or total knee replacement (total knee arthroplasty, TKA) leads to better clinical and functional outcomes in…
- Trial name
- UKA vs TKA (NCT07257211)
- Testing
- unicompartmental knee arthroplasty, total knee arthroplasty
- Where
- Austria
- Volunteers
- 102 people
- Sponsor
- Medical University of Graz
Osteoarthritis, Post-traumatic Arthritis
Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEM
This is a postmarketing study to assess the overall performance and survivorship of the SIGMA HP® PARTIAL KNEE SYSTEM.
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Gout, Pseudo-gout
- Trial name
- NCT01529099
- Testing
- SIGMA HP PARTIAL KNEE
- Where
- 3 sites in Italy, Switzerland
- Volunteers
- 64 people
- Sponsor
- DePuy International
Knee Osteoarthritis, Total Knee Arthroplasty
Improved Pain Management in Knee Osteoarthritis-related Surgeries
In recent years, pain management coordinated with enhanced recovery after surgery (ERAS) has been widely applied and rapidly developed in orthopedics, showing promising prospects.
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Unicompartmental Knee Arthroplasty, High Tibial Osteotomy
- Trial name
- NCT06124170
- Testing
- Preoperative pain managment, Intraoperative pain managment, Postoperative pain managment
- Where
- China
- Volunteers
- 714 people
- Sponsor
- Peng Liu
Osteoarthritis, Knee
Unicompartmental Knee Arthroplasty (UKA) Versus Total Knee Arthroplasty (TKA) of Medial Osteoarthritis
This study allows patients to take part of the decision making between a unicompartment knee (partial ) or a total Knee replacement .
- Trial name
- NCT03457051
- Testing
- Total Knee Arthroplasty (TKA), Unicompartmental Knee Arthroplasty (UKA)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee
Effect of Hydrotherapy After Unilateral UKA
Osteoarthritis (OA) is a progressive disease of the synovial joints that causes joint pain and limitation of function resulting in considerable morbidity and impairment of quality of life.
- Trial name
- NCT06459960
- Testing
- Hydrotherapy, Convention
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Arthritis, Osteoarthritis
A Comparison of Patients Receiving a Unicompartmental Knee Replacement With Robotic Assistance or With Conventional Instrumentation
A unicompartmental (partial) knee replacement (UKR) is the removal of one part of the knee joint (a condyle), that has become damaged due to osteoarthritis, and replacing it with an artificial implant.
- Conditions
- Arthritis, Osteoarthritis, Knee, Joint Diseases
- Trial name
- NCT04992078
- Testing
- NAVIO/CORI Surgical System, Non-robotic conventional instrumentation
- Where
- 6 sites in Ireland, United Kingdom
- Sponsor
- Smith & Nephew Orthopaedics AG
Arthroplasty, Replacement, Knee
Triathlon® Partial Knee Replacement (PKR) Outcomes Study
The purpose of this study is to compare the 10-year Knee Society Score (KSS) functional results of the Triathlon PKR Unicondylar Knee to the 10-year Knee Society Score (KSS) functional results of the Triathlon Cruciate Retaining…
- Trial name
- PKR (NCT00966979)
- Testing
- Triathlon PKR
- Where
- 9 sites in United States, Germany and 2 more
- Volunteers
- 111 people
- Sponsor
- Stryker Orthopaedics
OA Knee, OA Knee Pain
Comparison of Medial Knee Pain Between Patients With and Without Preoperative Tibia Vara Underging Mobile-bearing Unicompartmental Knee Arthroplasty
to compared VAS for medial knee pain between oa knee with or without tibia vara following mobile bearing UKA
- Conditions
- OA Knee, OA Knee Pain, Osteoarthritis
- Trial name
- bow leg (NCT07720024)
- Testing
- mobile bearing UKA
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Thammasat University
Knee Osteoarthritis
Comparison of Proprioception for HTO (High Tibial Osteotomy) and UKA (Unicompartmantal Knee Arthroplasty)
Osteoarthritis of the knee (KOA), a common degenerative joint disease, affects a significant part of the world's population. Although it can hold all the compartments in the knee joint, isolated medial compartment involvement has…
- Trial name
- NCT05993637
- Testing
- Examination of propriception
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Lower Limb Arthroplasty Under Chloroprocaine Spinal Anesthesia
Intrathecal Chloroprocaine for Lower Limb Arthroplasty
This study evaluates the perioperative course in adult patients undergoing total or partial knee arthroplasty, or total hip arthroplasty under chloroprocaine spinal anesthesia.
- Trial name
- NCT05365074
- Testing
- Chloroprocaine Injection
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hôpital de la Croix-Rousse
Arthroplasty, Replacement, Knee, Unicompartmental Knee Arthroplasty
Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral)
The overall aim of this trial is to compare functional and patient-reported outcomes and to assess the safety and effectiveness and long-term performance of the Smith+Nephew Robotic Systems for Unicompartmental Knee Replacements…
- Trial name
- NCT06036212
- Testing
- Robotic System, Conventional
- Where
- 5 sites in United Kingdom
- Sponsor
- Smith & Nephew, Inc.
Knee Osteoarthritis
The Effects of Surgical Wait Time for Knee Arthroplasty Quality of Life in Patients Awaiting Knee Arthroplasty
This study prospectively evaluates the effect of surgical wait time on knee function, pain and quality of life in patients waiting for knee arthroplasty (TKA or PKA)
- Trial name
- SIT'NWAIT (NCT06127719)
- Testing
- questionnaires
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Dijklander Ziekenhuis
Osteoarthritis, Avascular Necrosis
Persona Partial Knee Clinical Outcomes Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for the commercially available Persona Partial Knee System.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Conditional Tibial Condyle or Plateau Fractures
- Trial name
- NCT03034811
- Testing
- Persona Partial Knee system
- Where
- 24 sites in United States, Austria and 8 more
- Volunteers
- 757 people
- Sponsor
- Zimmer Biomet
Unicompartmental Knee Arthroplasty
Univation® X Follow-Up Study
The study is designed as a monocentric, prospective, observational, comparative follow-up study based on two previously treated patient groups.
- Trial name
- NCT03201172
- Testing
- Primary Unicompartmental Knee Arthroplasty
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- Aesculap AG
Osteo Arthritis Knee
Trial of Unicompartmental Versus Total Knee Arthroplasty
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
- Trial name
- NCT03385759
- Testing
- Unicompartmental knee arthroplasty, Total knee arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Anderson Orthopaedic Research Institute
Knee Osteoarthritis, Knee Arthritis
Performance of MOTO Medial® Unicompartmental Knee Arthroplasty
This is a prospective, multi-center study, designed to assess mid-term performance of the MOTO Medial® Unicompartmental Knee Arthroplasty (UKA), with patient report outcomes, clinical findings and radiographic analysis.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Trial name
- NCT03211663
- Testing
- MOTO Medial® UKA
- Where
- 5 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteoarthritis
Out Patient Surgery for Total Knee and Hip Replacement and Unicompartmental Knee Replacement - a Feasibility Study
The purpose of this study is to evaluate feasibly of outpatient Total Knee Replacement, Total Hip Replacement and Unicompartmental Knee Replacement in a modern fast-track setup.
- Trial name
- NCT02544620
- Testing
- Does fulfil of discharge criteria on the day of the surgery, Does not fulfil of discharge criteria on the day of the surgery
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Kirill Gromov
Primary Gonarthrosis, Genu Recurvatum
The Results of Oxford Unicompartmental Knee Arthroplasty in Patients With and Without Preoperative Genu Recurvatum
The purpose of this study is to explore the effects of the Oxford unicompartmental knee arthroplasty on two groups of patients, namely one with genu recurvatum before the procedure and one without.
- Trial name
- NCT02854189
- Testing
- Oxford unicompartmental knee arthroplasty
- Volunteers
- 104 people
- Sponsor
- Thammasat University
Osteoarthritis, Knee
Cemented Versus Cementless Unicompartmental Knee Arthroplasty
Unicompartmental knee replacement for selected cases of osteoarthritis is less invasive than total knee replacement. It gives better range of movement; patients stay for shorter time in the hospital and have a more natural feel…
- Trial name
- NCT05935878
- Testing
- Cementless Oxford Unicompartmental Knee Arthroplasty, Cemented Oxford Unicompartmental Knee Arthroplasty
- Volunteers
- 47 people
- Sponsor
- Oxford University Hospitals NHS Trust
Arthritis
Univation X Partial Knee Study
The objective of this study is to investigate the functional and clinical outcome after medial unicompartmental knee replacement using the Aesculap AG Univation X knee prosthesis compared to pre-operative data and a healthy…
- Trial name
- NCT04913974
- Testing
- Uni-condylar knee arthroplasty
- Where
- United Kingdom
- Sponsor
- Golden Jubilee National Hospital