Clinical trials: Unsafe Sex
Emergency Contraception
Safety and Efficacy of CDB-2914 for Emergency Contraception
The purpose of this study is to assess the safety and efficacy of CDB-2914 for preventing pregnancy when taken 3 to 5 days after unprotected sexual intercourse.
- Trial name
- NCT00411684
- Testing
- CDB-2914
- Where
- 17 sites in United States
- Volunteers
- 1,623 people
- Sponsor
- HRA Pharma
HIV Seropositivity, HCV Infection
HIV and HCV Infections in 2 Communes From the Battambang Province, Cambodia: Prevalence Rates, Viral Strains, and Unsafe Injection Practices (12352 ANRS ROK INVEST)
This cross-sectional survey will be conducted prospectively in 2 communes in the Battambang Province, Roka and Prey Khpos commune.
- Trial name
- NCT04044586
- Where
- Cambodia
- Volunteers
- 1,098 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections
Project ICARE: Intervening for Community Awareness, Respect, & Empowerment
This project will test the efficacy of a behavioral intervention to reduce sexual risk for HIV infection among African American Men who Have Sex with Men (MSM).
- Trial name
- NCT00712088
- Testing
- Project ICARE, HCT
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Alcohol Drinking, Sex, Unsafe
Alcohol and "Heat of the Moment" Sexual Decision Making
HIV transmission remains a significant public health concern, especially among men who have sex with men (MSM). Condomless anal intercourse (CAI) continues to be the major route of transmission for MSM.
- Conditions
- Alcohol Drinking, Sex, Unsafe, Hiv
- Trial name
- NCT05729256
- Testing
- Self-Regulation Intervention, Brief Advice and Information
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Alcohol; Harmful Use, Sex, Unsafe
MI With Text Messaging to Reduce Sexual Risk and Hazardous Drinking Among MSM
This is a small pilot study to provide effect size estimates for a brief intervention designed to reduce hazardous drinking and sexual risk behavior among men who have sex with men.
- Trial name
- MI&TXT4MSM (NCT03755661)
- Testing
- MI&TXT4MSM
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Sexual Behavior, Unprotected Sex
An Evaluation of Re:MIX: a Teen Pregnancy Prevention Program With Young Parents as Peer Educators, EngenderHealth
This study uses a cluster-level randomized controlled design to evaluate the efficacy of Re:MIX in reducing the incidences of early sexual behavior, unprotected sex, oral sex, pregnancy, and STIs.
- Trial name
- NCT03114410
- Testing
- Re:MIX, a multi-layer comprehensive teen pregnancy prevention intervention aimed at reducing pregnancy and STIs among youth ages 13-17
- Where
- United States
- Volunteers
- 621 people
- Sponsor
- Child Trends
Alcohol Consumption, Unsafe Sex
Brief Interventions in the Emergency Department for Alcohol and HIV/Sexual Risk
This brief alcohol and sexual risk taking intervention has the potential to influence the public health by reducing alcohol use and sexual risk taking behavior in individuals who are seeking treatment in an Emergency Department.
- Trial name
- SAFER (NCT01351389)
- Testing
- Brief Motivational Intervention (BMI), Brief Advice
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Brown University
Binge Drinking, Unsafe Sex
Individual and Contextual Factors That Influence Sexual Decisions
For decades, men who have sex with men (MSM) have carried the heaviest burden associated with the HIV epidemic in the United States.
- Conditions
- Binge Drinking, Unsafe Sex, HIV/AIDS, Sexually Transmitted Diseases
- Trial name
- NCT03224416
- Testing
- Alcohol Administration, No Alcohol Administration
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brown University
Unsafe Sex
Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults
The number of late middle-age and older adults living with HIV/AIDS in the U.S. continues to rise due largely to better clinical care and the improved efficacy of highly active antiretroviral therapy that has extended the lives…
- Trial name
- MI (NCT01499706)
- Testing
- 1-session of telephone-administered motivational interviewing, 4-session telephone-administered motivational interviewing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio University College of Osteopathic Medicine
Risk Behavior, Sex, Unsafe
BEing Safe in Treatment
Prior research has shown that many individuals with substance use disorders engage in HIV/sexual risk behaviors, and could strongly benefit from HIV prevention interventions that were delivered as part of their substance abuse…
- Conditions
- Risk Behavior, Sex, Unsafe, Substance Use, Risk Reduction
- Trial name
- BEST (NCT03575585)
- Testing
- BEST assessment only, BEST assessment plus feedback report, Standard Counselor Training
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Use, Drug Use
Trial of an Adapted STD Screening and Risk Reduction Intervention
The goal of this research study is to evaluate the impact of a paraprofessional-delivered, culturally adapted, evidence-based intervention (EBI) on sexually transmitted disease (STD), substance use and poor mental/emotional…
- Conditions
- Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea
- Trial name
- NCT02513225
- Testing
- Project EMPWR, Optimized Standard Care (OSC)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Help-Seeking Behavior, Pre-exposure Prophylaxis Use
Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men.
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Trial name
- NCT07475702
- Testing
- Moon and Sun Brothers: A Community Prevention Intervention
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- San Francisco State University
HIV Infections
Proyecto SOL: A Risk Reduction Intervention for Hispanic Men Who Have Sex With Men (MSM)
The purpose of this project is to determine the acceptability, feasibility, and the preliminary efficacy of an HIV prevention behavioral intervention (Proyecto SOL) to reduce behaviors associated with HIV acquisition among…
- Trial name
- NCT00690976
- Testing
- Proyecto SOL, HCT
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV, Adherence
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive…
- Conditions
- HIV, Adherence, Sexual Behavior, HIV Infections
- Trial name
- Cell-POS (NCT01118767)
- Testing
- Cell phone intervention
- Where
- 2 sites in Peru
- Volunteers
- 210 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Methamphetamine Abuse, HIV/AIDS
FASTLANE II: Reducing Sex, Drug, and Mental Health Risk
The study uses a repeated measures, single group pretest-posttest design methodology to examine the feasibility, acceptability, and preliminary effectiveness of the FASTLANE II intervention aimed at decreasing risky sex behaviors…
- Conditions
- Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
- Trial name
- FLII (NCT04109014)
- Testing
- FASTLANE II
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Unsafe Sex
Construction of a Risky Sexual Behaviour Intervention Programme for College Students Based on BCW Theory
Using the intervention functions of Behavior Change Wheel (BCW) and BCTs, we constructed an intervention program for college students' risky sexual behaviors by combining literature analysis, qualitative research, Delphi's expert…
- Trial name
- NCT06435234
- Testing
- risky sexual behavior intervention
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rong Zhang
Economic Hardship, Condomless Sex
Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)
The study team will conduct a two-group study to examine the efficacy of implementing a combination intervention to improve economic stability and HIV preventive behaviors. The team will enroll approximately 500 young adults.
- Conditions
- Economic Hardship, Condomless Sex, Utilization, Health Care
- Trial name
- ENSPIRE (NCT06096324)
- Testing
- Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Substance-related Disorders, Depression
Primary Care iSBIRT to Reduce Serious Teen Health Risks
The goal of the project is to develop and test an internet/intranet-based Screening, Brief Intervention, and Referral to Treatment (iSBIRT) system for adolescents that targets a broad range of serious health-risks and problem…
- Conditions
- Substance-related Disorders, Depression, High-risk Sex
- Trial name
- NCT00891631
- Testing
- iSBIRT, iSBIRT/TE
- Where
- United States
- Sponsor
- Boston Children's Hospital
HIV Infections
Project HERMITAGE: HIV Prevention in Hospitalized Russian Drinkers
The objective of this study is to test in a randomized controlled trial the effectiveness of a US secondary HIV prevention program to reduce HIV risk behaviors, STD acquisition, and alcohol consumption among HIV-infected Russians…
- Trial name
- NCT00483483
- Testing
- Individual and group HIV risk behavior counseling sessions, health education and support group
- Where
- 3 sites in Russia
- Volunteers
- 700 people
- Sponsor
- Boston Medical Center