Clinical trials: Unspecified Adult Solid Tumor, Protocol Specific, completed
Unspecified Adult Solid Tumor, Protocol Specific
Halofuginone Hydrobromide in Treating Patients With Progressive Advanced Solid Tumors
RATIONALE: Halofuginone hydrobromide may stop the growth of solid tumors by stopping blood flow to the tumor. PURPOSE: Phase I trial to study the effectiveness of halofuginone hydrobromide in treating patients who have…
- Trial name
- NCT00027677
- Testing
- halofuginone hydrobromide
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 25 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Unspecified Adult Solid Tumor, Protocol Specific
In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer
RATIONALE: Tissue plasminogen activator and captopril may help the body generate angiostatin. Angiostatin may stop the growth of cancer by stopping blood flow to the tumor.
- Trial name
- NCT00086723
- Testing
- recombinant tissue plasminogen activator, captopril
- Where
- United States
- Sponsor
- Northwestern University
Unspecified Adult Solid Tumor, Protocol Specific
EF5 in Treating Patients With Solid Tumors
Diagnostic procedures using the drug EF5 to detect the presence of oxygen in tumor cells may help to plan effective treatment for solid tumors.
- Trial name
- NCT00003282
- Testing
- EF5, therapeutic conventional surgery, biopsy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Unspecified Adult Solid Tumor, Protocol Specific
UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of resveratrol may prevent cancer.
- Trial name
- IRB 2004-535 (NCT00098969)
- Testing
- resveratrol
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia
Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Baclofen-amitriptyline-ketamine (BAK) gel may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether BAK gel is more effective than a placebo in treating peripheral neuropathy caused by…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00516503
- Testing
- baclofen/amitriptyline/ketamine gel
- Where
- 165 sites in United States
- Volunteers
- 208 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Dermatologic Complications, Unspecified Adult Solid Tumor, Protocol Specific
Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer
RATIONALE: Topical sunscreen may be effective in preventing skin rash caused by treatment with drugs such as erlotinib or cetuximab.
- Trial name
- NCT00362986
- Testing
- sunscreen
- Where
- 208 sites in United States
- Volunteers
- 116 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Unspecified Adult Solid Tumor, Protocol Specific
Motivational Program for Smokers Enrolled in a Methadone Maintenance Program
RATIONALE: Stop-smoking programs may help patients stop smoking and prevent cancer from forming. PURPOSE: This clinical trial is studying how well a motivational program works in helping smokers enrolled in a methadone…
- Trial name
- NCT00278226
- Testing
- smoking cessation intervention, educational intervention
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- Butler Hospital
Unspecified Adult Solid Tumor, Protocol Specific
Dasatinib and Lapatinib Ditolsylate in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery
RATIONALE: Dasatinib and lapatinib ditoslylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00662636
- Testing
- dasatinib, lapatinib ditosylate, pharmacological study
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Unspecified Childhood Solid Tumor, Protocol Specific
Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
This phase I trial studies the side effects and the best dose of temsirolimus when given together with irinotecan hydrochloride and temozolomide in treating younger patients with recurrent or refractory solid tumors.
- Trial name
- NCT01141244
- Testing
- temsirolimus, temozolomide, irinotecan hydrochloride
- Where
- 25 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- National Cancer Institute (NCI)
Unspecified Adult Solid Tumor, Protocol Specific, Cancer
Safety and Dosage Study of RAD001 (Everolimus) in Combination With Current Standard of Care to Treat Advanced Solid Tumors.
The purpose of this study is to determine if RAD001 (everolimus) helps improve the standard treatment of XELOX-A (bevacizumab, oxaliplatin, capecitabine) in advanced solid tumors.
- Trial name
- COBRA (NCT00849550)
- Testing
- capecitabine/oxaliplatin/bevacizumab/RAD001 (XELOX-A-Ev)
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Herbert Hurwitz
Unspecified Adult Solid Tumor, Protocol Specific
Green Tea Extract in Treating Patients With Advanced Solid Tumors
RATIONALE: Green tea extract contains ingredients that may slow the growth of certain cancers, as well as prevent the development of new cancers.
- Trial name
- NCT00003197
- Testing
- green tea extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Unspecified Adult Solid Tumor, Protocol Specific
Computed Tomography in Detecting Movement of the Esophagus in Patients Undergoing Radiation Therapy to the Chest
RATIONALE: Comparing results of diagnostic procedures, such as computed tomography scan (CT scan), done before and after radiation therapy to help detect movement of the esophagus may help doctors plan the best treatment.
- Trial name
- NCT00433524
- Testing
- computed tomography
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Fox Chase Cancer Center
Unspecified Adult Solid Tumor, Protocol Specific
Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as methoxyamine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00892385
- Testing
- Methoxyamine, Temozolomide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Case Comprehensive Cancer Center
Unspecified Adult Solid Tumor, Protocol Specific
Combination Chemotherapy in Treating Patients With Advanced Cancer
Phase I trial to study the effectiveness of combining flavopiridol, fluorouracil, and leucovorin with or without irinotecan in treating patients who have advanced cancer.
- Trial name
- NCT00021073
- Testing
- alvocidib, leucovorin calcium, fluorouracil
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute (NCI)
Unspecified Adult Solid Tumor, Protocol Specific
Smokefree.Gov Website in Helping United States Federal Employees Quit Smoking
RATIONALE: Stop-smoking information on the smokefree.gov website may help people quit smoking and remain a nonsmoker. PURPOSE: This clinical trial is studying how well the smokefree.gov website works with an electronic bulletin…
- Trial name
- NCT00245076
- Testing
- smoking cessation intervention, internet-based intervention
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
ABC294640 in Treating Patients With Advanced Solid Tumors
This phase I trial studies the side effects and best dose of ABC294640 in treating patients with advanced solid tumors. ABC294640 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- ABC-101 (NCT01488513)
- Testing
- sphingosine kinase-2 inhibitor ABC294640
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- RedHill Biopharma Limited
Unspecified Adult Solid Tumor, Protocol Specific
3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in…
- Trial name
- NCT00004213
- Testing
- triapine
- Where
- 2 sites in United States
- Sponsor
- Vion Pharmaceuticals
Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific
Combination Chemotherapy in Treating Patients With Advanced Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00003956
- Testing
- fluorouracil, leucovorin calcium, lonafarnib
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Docetaxel and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00390429
- Testing
- docetaxel, erlotinib hydrochloride
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of California, Davis