Clinical trials: Untreated
Visible Light Exposure on Healthy Back Skin
Agents Effect Under Visible Light on Caucasian, Asian and Darker Skin Types
The study intends to get knowledge on pigmentation induced by visible light on Asian/Chinese skin type and darker skin type, and to evaluate and to compare with a non-treated control zone and between them, the efficacy of…
- Trial name
- VLAD (NCT07462845)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Wound Healing
A Study to Assess Wound Healing Efficacies of Different Clean, Treat, and Protect Wound Care Regimens Compared to Standard of Care and Untreated
The purpose of this study is to evaluate the healing rates of wounds treated with various wound care regimens including antiseptic wound wash, topical antibiotic treatment, adhesive bandages, and/or hydrocolloid bandages.
- Trial name
- NCT05045183
- Testing
- SoC Adhesive Bandage, Antibiotic Ointment, Antiseptic Wash
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Lymphocytic Leukemia
This Study is Being Performed to Evaluate the Effect of Genasense on the Efficacy and the Safety of Rituximab/Fludarabine Combination Treatment in Previously Untreated Subjects With Chronic Lymphocyctic Leukemia(CLL)
To compare the efficacy and safety of combination treatment with Genasense, fludarabine, and rituximab versus combination treatment with fludarabine and rituximab in previously untreated subjects with CLL.
- Trial name
- NCT00517218
- Testing
- Genasense® (, oblimersen sodium G3139)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Genta Incorporated
Visible Light Exposure on Healthy Back Skin
Determine the Photoprotection Efficacy of Seven Sunscreen Products Under Visible Light Exposure.
To evaluate the protective effect of seven sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796179
- Testing
- Visible Light Exposure - Treated zones with sunscreen products, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Efficacy of Sunscreen Products, Healthy Back Skin
Evaluation of the Photoprotection Efficacy with Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Conditions
- Efficacy of Sunscreen Products, Healthy Back Skin, Pigmentation Induced by Visible Light Exposure
- Trial name
- NCT06803901
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Infant, Small for Gestational Age
Safety Study In Patients Who Were Born Small And Short And Were Treated With Growth Hormone To Achieve Normal Height
The purpose of this study is to demonstrate that insulin sensitivity is not different between growth hormone - treated subjects who are small for gestational age (SGA) and an SGA cohort of subjects matched by gender and body mass…
- Trial name
- NCT00396474
- Testing
- post GH treatment observational study
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Study the Protection Potency of Sunscreen Products Against Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficacy of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796192
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Hyperlipoproteinemia Type I
Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies
LPL (Lipoprotein Lipase) is an enzyme which plays an important role in the elimination of triglycerides (fat) and the clearance of dietary fat particles known as chylomicrons (CM) in the blood.
- Trial name
- NCT01447901
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Amsterdam Molecular Therapeutics
Gaucher Disease
Omics Gaucher Study: Multiomic Approach
The study aims to investigate the transcriptomic and metabolomic changes in blood, plasma and isolated monocytes from Gaucher patients and healthy controls.
- Trial name
- OmicsGaucher (NCT05526664)
- Testing
- Genetic testing and Omics analysis
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- CENTOGENE GmbH Rostock
Small Cell Lung Carcinoma Extensive Disease
Durvalumab Plus Chemotherapy in Untreated Patients With Extensive-Stage Small Cell Lung Cancer
This is a Phase IIIb, interventional, single arm, multicentre study to evaluate safety, effectivenees, use of resources and patient reporting outcomes in patients with ES-SCLC treated with durvalumab in combination with…
- Trial name
- CANTABRICO (NCT04712903)
- Testing
- Durvalumab, Cisplatin, Etoposide
- Where
- 34 sites in Spain
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Kidney Neoplasms
A Study to Evaluate the Safety and Efficacy of Nivolumab With Ipilimumab in Participants With Untreated Advanced Kidney Cancer Conducted in India
The purpose of this study is to assess the safety and efficacy of nivolumab combined with ipilimumab in intermediate and poor-risk participants with previously untreated advanced renal cell carcinoma (RCC) or metastatic RCC…
- Trial name
- CheckMate 7C9 (NCT04513522)
- Testing
- Nivolumab, Ipilimumab
- Where
- 11 sites in India
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy
Assessment of the Effect of the Product RV2666C Formula LA2984 Compared to an Untreated Area With an Epidermally Ablated Skin Model Obtained With an Erbium YAG Laser on Adults Presenting IV to VI Skin Phototype
In this study, we assess the efficacy of a cosmetic product in adults with IV to VI skin phototype. This study is conducted as a monocentric, controlled, compared with an untreated area and randomized for the area of product…
- Trial name
- NCT07166484
- Testing
- Cosmetic product RV2666C LA2984
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Wounds, Wound Healing
Tyrosur® Gel-Investigation on Wound Healing Efficacy
This IIa study with intraindividual comparison of treated versus untreated to assess the wound healing efficacy of Tyrosur® Gel after experimental impairment of the skin using an abrasive wound healing model.
- Trial name
- NCT01227759
- Testing
- Drug containing the active ingredient
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Engelhard Arzneimittel GmbH & Co.KG
Posterior Blepharoconjunctivitis
A Four Week, Open-Label Study of Azithromycin Ophthalmic Solution, 1% (P08641)
One objective of this study is to determine the levels of markers of inflammation on the eyelid margin of subjects with blepharoconjunctivitis and compare them with those of healthy volunteers.
- Trial name
- NCT01220258
- Testing
- Azithromycin ophthalmic solution, 1%
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Prediabetes, Type 2 Diabetes
Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Given the data on the active ingredients of Totum-63, this research aims to evaluate the effect of its chronic consumption (24 weeks) on glucose and lipid homeostasis and especially on fasting plasma glucose in volunteers with…
- Conditions
- Prediabetes, Type 2 Diabetes, Hypertriglyceridemia, Obesity
- Trial name
- TOTUM-63 TWO (NCT02868177)
- Testing
- Totum-63
- Where
- 6 sites in France, Ireland and 2 more
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Visible Light Exposures on Healthy Back Skin
Photoprotection Efficacy of a Sunscreen Under Visible Light Exposure by Using Two Different Simulators
To assess the ability of a protected agent to prevent the pigmentation under visible light exposures (VL) using two different simulators in healthy volunteers
- Trial name
- NCT06796140
- Testing
- Visible Light Exposure - Treated zone - Left hemi-back, Visible Light Exposure - Treated zone - Right hemi-back, Visible Light Exposure - Untreated zone - Left hemi-back
- Where
- Romania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Nocturnal Enuresis
A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis
To evaluate the overall response to desmopressin treatment among previously untreated enuretic children aged 5-15 years after 3 and 6 months of treatment.
- Trial name
- DRIP (NCT00245479)
- Testing
- Primary nocturnal enuresis
- Where
- France
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Visible Light Exposure, Healthy Back Skin
Photoprotection Efficacy of Four Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of four sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796010
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Study the Potency of Sunscreen to Protect Against the Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficiency of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796088
- Testing
- Treated zones exposed to Visible Light source, Untreated zone exposed to Visible Light source
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Healthy Subjects, Overactive Bladder
An Exploratory Study to Investigate Bladder Contractions in the Storage Phase and Related Bladder Sensations in Healthy Females and Females With Overactive Bladder (OAB) Using High Resolution and Conventional Urodynamics
This study aims to identify differences in bladder contractions during the storage phase (non voiding activities) between OAB subjects and healthy subjects, using high resolution urodynamics.
- Trial name
- NCT01540786
- Testing
- High resolution urodynamic assessment, Conventional urodynamic assessment
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe Ltd.