Clinical trials: Upper Abdominal Surgeries
Analgesia, Epidural
Neuraxial Ultrasound for Thoracic Epidural Placement
This blinded, randomized study compares standard palpation to ultrasound-assisted landmark identification of the thoracic spine for thoracic epidural catheterization.
- Trial name
- NCT02785055
- Testing
- Thoracic Epidural Placement, Bupivacaine 0.05%, Hydromorphone 0.01mg/mL
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Abdominal Surgery
Effects of the Breath Stacking Technique After Upper Abdominal Surgery
This study evaluates the effects of the breath stacking technique in patients after upper abdominal surgery. Half of the patients receive routine physical therapy associated with the Breath Stacking technique, while the other…
- Trial name
- NCT04418700
- Testing
- Breath Stacking
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Santa Maria
Post Operative Pain, Acute
Quadratus Lumborum vs Caudal Epidural Block for Perioperative Analgesia in Pediatric Patients for Upper Abdominal Surgeries
Compare between the analgesic effect of the Ultrasound-guided quadratus lumborum block and single Caudal epidural injection in pediatric patients undergoing surgeries with supraumbilical incisions.
- Trial name
- NCT05493085
- Testing
- Quadratus lumborum block, Caudal epidural injection
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Paediatric, Surgery
Erector Spinae Plane Block for Paediatric Upper Abdominal Surgery
Upper abdominal surgeries are associated with severe postoperative pain. Thus, maintaining effective postoperative analgesia in the paediatric age group is very crucial in terms of future pain perception and chronic pain…
- Conditions
- Paediatric, Surgery, Analgesia, Anesthesia
- Trial name
- NCT04518215
- Testing
- Erector Spinae Plain Block, Intra-Venous Analgesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nazmy Edward Seif
Post-Op Complication
Suprapubic Transverse Incision With Rectus Release for Upper Peritoneal Access): A Novel Dual-Plane Technique for Abdominal Wall Incision in Complex Gynecological Surgery
This study aims to evaluate the clinical effectiveness, anatomical benefits, and postoperative outcomes of the STIRRUP incision (Suprapubic Transverse Incision with Rectus Release for Upper Peritoneal Access) by comparing…
- Trial name
- NCT07373886
- Testing
- STIRRUP (Suprapubic Transverse Incision with Rectus Release for Upper Peritoneal access) technique
- Volunteers
- 50 people
- Sponsor
- Cairo University
Ileus
Thoracic Epidural for Postoperative Ileus
The investigators try to find whether thoracic epidural analgesia (TEA) shortens the first gas-out time compared to iv-PCA and promotes earlier discharge after major upper abdominal surgery.
- Trial name
- NCT02491385
- Testing
- thoracic epidural analgesia, iv-PCA
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Samsung Medical Center
Pain, Postoperative
Lidocaine as an Anesthetic Adjuvant in Liver and Gastric Laparoscopic Surgery
The aim is to analyze the effect of intravenous lidocaine administration on postoperative opioid use in patients undergoing upper abdominal cancer surgery.
- Trial name
- NCT04584749
- Testing
- Lidocaine Iv
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Esophageal Cancer, Gastric Cancer
Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer
In line with improvements in oncologic outcome for patients with esophageal cancer, the attritional impact of curative treatment with respect to functional status and health-related quality of life (HR-QL) in survivorship is…
- Conditions
- Esophageal Cancer, Gastric Cancer, Sarcopenia, Sarcopenic Obesity
- Trial name
- NCT03061370
- Testing
- Esophagectomy or Gastrectomy
- Where
- 2 sites in Ireland
- Volunteers
- 317 people
- Sponsor
- St. James's Hospital, Ireland
Postoperative Complications
Autogenic Drainage Effect on Blood Gases and Prevention of Pulmonary Complication After Upper Abdominal Surgery
Purpose: This study will find out the effect of Autogenic drainage on the prevention of pulmonary complications after upper abdominal surgery.
- Trial name
- NCT04446520
- Testing
- autogenic drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Acupuncture, Transcutaneous Electrical Nerve Stimulation
Acupuncture Versus Transcutaneous Electrical Nerve Stimulation on Pain Post Upper Abdominal Surgeries
This study was done to: Determine the therapeutic efficacy of acupuncture as physical therapy approach in minimizing pain post upper abdominal surgeries.
- Conditions
- Acupuncture, Transcutaneous Electrical Nerve Stimulation, Pain, Upper Abdominal Surgery
- Trial name
- NCT07036393
- Testing
- Acupuncture, Transcutaneous electrical nerve stimulation, drugs
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Post Operative Pain
Postoperative Analgesia in Patients Undergoing Open Upper Abdominal Surgeries: External Oblique Intercostal Plane Block vs. Quadratus Lumborum Block
Open upper abdominal surgeries with subcostal incisions are a cause of severe pain and can lead to pulmonary and cardiac complications, detrimental physiological effects, and may also have psychological, economic, and social…
- Trial name
- NCT07094386
- Testing
- External Oblique Intercostal Plain Block, Quadratus Lumborum Block, Bupivacaine %0.25 (isobaric)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Major Upper or Lower Abdominal Surgery
A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Major Abdominal Surgery
The purpose of this study is to evaluate dosages of ARX-F01 (opioid pain medication) versus a placebo (or sugar pill) for the treatment of post-operative pain in subjects following abdominal surgery.
- Trial name
- NCT00718081
- Testing
- Oral sufentanil
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Talphera, Inc
Postoperative Pain
A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery
The primary purpose of this study is to evaluate the effects of lidocaine/epinephrine test dose administration on the PK profile of a single epidural dose of DepoDur (extended-release epidural morphine) in patients undergoing…
- Trial name
- NCT00728832
- Testing
- DepoDur (extended-release epidural morphine)
- Volunteers
- 39 people
- Sponsor
- EKR Therapeutics, Inc
Perioperative Analgesia in Major Upper Abdominal Surgery
Regional Block for Upper Abdominal Surgeries
Pain control after major upper abdominal surgeries is an essential step to guard against postoperative complications such as lung atelectasis. This major step can be achieved by opioids or regional blocks.
- Trial name
- NCT05691933
- Testing
- Block group, Morphine infusion
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Ultrasound, Rhomboid Intercostal Plane Block
Ultrasound Guided Rhomboid Intercostal Plane Block Versus Thoracic Erector Spinae Plane Block in Upper Abdominal Surgery
The aim of the work is to evaluate the analgesic efficacy of ultrasound guided rhomboid intercostal plane block versus ultrasound guided thoracic erector spinae block in patients undergoing upper abdominal surgery.
- Conditions
- Ultrasound, Rhomboid Intercostal Plane Block, Thoracic Erector Spinae Plane Block, Upper Abdominal Surgery
- Trial name
- NCT06654635
- Testing
- Rhomboid intercostal plane block, Erector spinae plane block, Control group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Anesthesia Induced Atelectasis
Which Ventilatory Strategy is Better for Lung in Upper Abdominal Surgeries?
Ventilated Patients especially those undergoing upper abdominal surgeries are prone to lung atelectasis. They are at risk of adverse effects secondary to inadequate lung ventilation.
- Trial name
- NCT04872361
- Testing
- Low PEEP, High PEEP, High PEEP/RM
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- Mansoura University
Acute Pain
Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery
This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.
- Trial name
- Rectus (NCT03725527)
- Testing
- Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pulmonary Atelectasis, Postoperative
Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery
the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include…
- Trial name
- LUS/PEEP/RM (NCT06654778)
- Testing
- PEEP, PEEP/RM, PEEP/RM/RF
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Abdomen Hernia, Respiratory Complication
Virtual Reality on Pulmonary Function After Upper Abdominal Surgeries
After upper abdomen surgery, respiratory muscle dysfunction is well recognised. After laparotomy and even laparoscopy, maximum static inspiratory and expiratory pressures are lowered, and recovery can take several days.
- Trial name
- NCT06301126
- Testing
- Virtual reality, conventional physical therapy exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University