Clinical trials: Upper Extremity Function, open to volunteers
Diaphragmatic Function, Metacarpal Fracture
Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine
The study aims to evaluation the effects of Liposomal Bupivacaine on diaphragmatic function in patients undergoing upper limb surgery who receive Interscalene Brachial Plexus Block.
- Conditions
- Diaphragmatic Function, Metacarpal Fracture, Radius Fracture, Peripheral Nerve Neurolysis
- Trial name
- NCT07263295
- Testing
- 0.5% Hydrochloride Bupivacaine 20ml, 0.5% Hydrochloride Bupivacaine 10ml, Liposomal Bupivacaine 10mL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang University
Hemiplegic Cerebral Palsy
Action Observation Versus Mirror Therapy in Children With Spastic Hemiplegic Cerebral Palsy
The goal of this clinical trial is to compare the effects of Action Observation therapy and Mirror therapy on hand grip strength and upper extremity function in children with hemiplegic cerebral palsy.
- Trial name
- NCT07739069
- Testing
- Mirror Therapy, Action Observation Therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Stroke
Physiotherapy/hypnosis for AVC Patients
Impact of physical therapy with hypnosis on the functional capacity of the upper limb in stroked patients.
- Trial name
- NCT06885294
- Testing
- Physiotherapy, Physiotherapy and Hypnosis, Control group Physiotherapy and Hypnosis
- Where
- Belgium
- Volunteers
- 84 people
- Sponsor
- University of Liege
Stroke
Robot-Assisted Tai Chi for Upper Limb Rehabilitation in Stroke Patients
This study aims to compare the effectiveness of Robot-Assisted Tai Chi Training (RATT) versus conventional rehabilitation in improving upper limb motor function post-stroke, and to explore the neuromuscular mechanisms of RATT.
- Trial name
- NCT06897631
- Testing
- Robot-Assisted Tai Chi Training, Conventional rehabilitation training
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Jing Tao
Stroke, Brain Disease
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
The goal of this study is to verify whether the use of deep brain stimulation can improve motor function of the hand and arm and speech abilities for people following a stroke.
- Conditions
- Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- NCT06303869
- Testing
- Deep Brain Stimulation (DBS) of the Motor Thalamus
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jorge Gonzalez-Martinez
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery
The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- NCT06701422
- Testing
- Intraoperative stimulation of the cervical spinal cord
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Columbia University
Stroke, Upper Extremity Paresis
BCI-FES for Upper Limb Rehabilitation in Chronic Stroke
The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulation therapy coupled to P-300…
- Conditions
- Stroke, Upper Extremity Paresis, Neuronal Plasticity
- Trial name
- BCI-FES (NCT06409754)
- Testing
- Functional Electrical Stimulation Therapy coupled to a P-300 based Brain-Computer Interface, Conventional Physical Therapy
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Hemiplegia, Stroke
Mirror vs Virtual Reality Therapy for Upper Extremity Function in Hemiplegic Patients
Upper extremity impairment in hemiplegic patients significantly impacts daily activities and reduces quality of life. Although traditional rehabilitation methods can help, some patients experience limited progress.
- Conditions
- Hemiplegia, Stroke, Upper Extremity Dysfunction
- Trial name
- NCT07018336
- Testing
- Mirror Therapy, Virtual Reality (VR) Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istinye University
Chronic Stroke
Robotic Rehabilitation Vs Occupational Therapy Chronic Stroke Upper Limb Rehabilitation
The functional recovery of the upper limb represents a critical element in post-stroke rehabilitation; hemiplegic/hemiparetic patients who achieve optimal recovery are a minority, and incomplete recovery has relevant consequences…
- Trial name
- REDIRECT (NCT06884553)
- Testing
- Robotic therapy (Gloreha Sinfonia system), Occupational therapy, Control
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Florence
Subacute Stroke, Upper Limb
Additional Effects of Kinesio-Taping Along with Conservative Physical Therapy on Upper Limb Function, Range of Motion and Spasticity in the Patients with Subacute Stroke
A randomized control trial will be done on diagnosed stroke patients of subacute stage in Fauji Foundation Hospital Rawalpindi and leading edge physical therapy and rehabilitation clinic.The purpose of the study is to determine…
- Conditions
- Subacute Stroke, Upper Limb, Range of Motion, Spasticity
- Trial name
- NCT06674057
- Testing
- KinesioTaping, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Athletic Performance, Upper Extremity
DEVELOPMENT AND PSYCHOMETRIC EVALUATION OF THE NEUROCOGNITIVE UPPER EXTREMITY TESTS: A RELIABILITY AND VALIDITY STUDY
The goal of this observational study is to develop an upper extremity neurocognitive performance test battery, determine its reliability and validity, and investigate the effect of neurocognitive load on test performance in…
- Conditions
- Athletic Performance, Upper Extremity, Cognition, Physical Functional Performance
- Trial name
- NCT07579676
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Obstructive Sleep Apnea, Sleep Apnea
Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.
- Trial name
- NCT07465874
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Stroke
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery of Paretic Upper Limb Function, Quality of Life, and Therapeutic Alliance in Women From the Araucanía Region Who Suffered a Stroke (CIMT + tDCS).
General Objective To determine the effects of a neurorehabilitation program based on Constraint-Induced Movement Therapy (CIMT) and non-invasive neuromodulation through cerebellar transcranial direct current stimulation (C-tDCS)…
- Trial name
- (CIMT - tDCS) (NCT07619703)
- Testing
- tDCS
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad de La Frontera
Amputation, Amputation, Traumatic
Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control
The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User
- Trial name
- NCT07011420
- Testing
- Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Stroke
High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Upper limb hemiparesis is the most common sequelae in patients, severely impacting their independence and quality of life. Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct…
- Trial name
- NCT06409143
- Testing
- HD-tES, UE rehabilitation, HD-tES (Bilateral)
- Where
- 3 sites in Taiwan
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Combined Effects of LIRT-BFR Therapy in Post- Stroke Patients
Stroke is a focal neurological deficit of sudden onset, with symptoms lasting more than 24 hours leading to consequences like impacting physical abilities, cognitive functions and emotional well-being, speech and language…
- Trial name
- NCT07646418
- Testing
- Low intensity resistance training with Blood flow restriction therapy, Conventional Physical Therapy Protocol
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Schizophrenia and Schizoaffective Disorder
Effects of RAS in SZ
The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics.
- Trial name
- NCT07086040
- Testing
- RAS incorporated in upper-limb movement training, Upper-limb movement training
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shu-Mei Wang
Functional Pituitary Adenomas
Study of 18FET PET in Functional Pituitary Adenomas With Indeterminate MRI Findings
Pituitary adenomas (PAs) are common benign tumors, but their potential for tumor aggression and hormone secretion make them serious tumors.
- Trial name
- FET-PIT (NCT07360548)
- Testing
- fluoroethyl-L tyrosine (18F)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Duchenne Muscular Dystrophy (DMD)
Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns Among Patients with Duchenne Muscular Dystrophy.
Objective: The objective of this observational study is to evaluate and quantify trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using computer vision technology.
- Trial name
- NCT06755138
- Testing
- Observational Assessment
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Acute Traumatic Spinal Cord Injury
NEUROwave - Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury
It has been hypothesized that there are two mechanisms of acute traumatic spinal cord injury (SCI): the primary mechanical damage and the secondary injury due to additional pathological processes initiated by the primary injury.
- Trial name
- NCT04474106
- Testing
- Shock waves, dummy head
- Where
- 15 sites in Austria
- Volunteers
- 246 people
- Sponsor
- AUVA