Clinical trials: Upper Extremity Function, open to volunteers
Neuromotor Impairments
Physical Therapy for Montana Children With NMD Using Hippotherapy and the Equine Environment
The goal of this pilot clinical trial is to determine if physical therapy incorporating horses can improve the motor skills of the arms in children 6-17 years old with neuromotor disorders (such as cerebral palsy, spinal muscular…
- Trial name
- NCT06887647
- Testing
- Physical Therapy Using Hippotherapy and the Equine Environment, Standard Play-Based Physical Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Montana
Spinal Cord Injury Cervical
Combining Spinal Cord Transcutaneous Stimulation and Activity-based Training in Inpatient Rehabilitation to Facilitate Upper Limb Function of Individuals with Acute to Subacute Cervical Spinal Cord Injury
The purpose of this clinical trial is to understand the safety and practicality of using spinal cord transcutaneous (through the skin) stimulation in an inpatient setting as well as how the combination of activity-based training…
- Trial name
- NCT06773286
- Testing
- Active Stimulation, Training only
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Stroke
TENS for Limb Function in Stroke: Design and Rationale for a Randomized Trial
This study tests whether slow or fast electrical nerve stimulation (TENS) works better to improve arm movement in people recovering from a stroke.
- Trial name
- NCT06997744
- Testing
- Low-frequency(2HZ) TENS, High-frequency(100HZ) TENS
- Where
- China
- Volunteers
- 156 people
- Sponsor
- CHENGNING Song
Stroke
FES-Assisted Upper Extremity Ergometer Training in Subacute Stroke
Stroke is a leading cause of long-term disability and often results in impaired upper extremity function and reduced aerobic capacity. Improving both cardiovascular and function is an important goal in stroke rehabilitation.
- Trial name
- FES-UE-EX (NCT07484854)
- Testing
- Upper Extremity Ergometer Training, FES-Assisted Upper Extremity Ergometer Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Chronic Stroke Patients
kTMP in Chronic Stroke
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- KULMINATE (NCT07277595)
- Testing
- kTMP 18 weeks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Spinal Cord Injury
Arm and Leg Cycling for Accelerated SCI Recovery
The purpose of this study is to examine interventions with paradigms involving upper and lower extremity cycling (A\&L cycling) with A\&L cycling with functional electrical stimulation (FES) (A\&L_FES group), A\&L cycling with…
- Trial name
- NCT06873776
- Testing
- A&L cycling, Body weight supported treadmill training (BWSTT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Functional Recovery, Upper Extremity Vascularized Composite Allotransplantation
Upper Extremity Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional Outcomes, and Patient-Reported Psychosocial Outcomes
The primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of upper extremity vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
- Trial name
- NCT07810790
- Testing
- Upper Extremity Vascularized Composite Allotransplantation (VCA)
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Tricuspid Regurgitation Functional, Tricuspid Regurgitation (TR)
Safety and Feasibility Study: Transcatheter Valve Repair in Severe Symptomatic Functional Tricuspid Regurgitation
The goal of this clinical trial is to evaluate the safety and technical success of the Tangent Tricuspid Annular Therapy System in patients with severe, symptomatic functional tricuspid regurgitation.
- Conditions
- Tricuspid Regurgitation Functional, Tricuspid Regurgitation (TR), Tricuspid Regurgitation
- Trial name
- NCT07140562
- Testing
- Tricuspid Annular Therapy System
- Where
- Paraguay
- Volunteers
- 25 people
- Sponsor
- Tangent Cardiovascular Inc.
Lateral Epicondylitis
A Comparison of the Effects of Combining ESWT With Blood Flow Restriction Therapy in Patients Diagnosed With Lateral Epicondylitis
Lateral epicondylitis is a chronic degenerative tendinopathy characterized by pain, tenderness, decreased grip strength, and functional limitations, particularly on the outer part of the elbow.
- Trial name
- NCT07782723
- Testing
- Blood Flow Restriction Therapy, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara Yildirim Beyazıt University
Upper Limb Dysfunction, Hand Function Impairment
3D-Printed Mobile Phone Holder for Individuals With Upper Limb Impairments
Individuals with upper limb functional impairments, such as those resulting from stroke, spinal cord injury, musculoskeletal disorders, or degenerative joint disease, often experience difficulties operating smartphones.
- Conditions
- Upper Limb Dysfunction, Hand Function Impairment, Musculoskeletal Disorders Affecting Hand Function, Difficulty Operating Smartphones Due to Upper Limb Impairment
- Trial name
- NCT07561944
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Stroke
Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)
Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb.
- Trial name
- NEUROMIROIR2 (NCT04119544)
- Testing
- Conventional rehabilitation, Intensive Visual Simulation
- Where
- 5 sites in France
- Volunteers
- 66 people
- Sponsor
- Clinique Les Trois Soleils
Stroke
Comparative Effects of Telerehabilitation and Clinic Based Constraint Induced Movement Therapy on Upper Limb Function in Sub-Acute Stroke Patients
Stroke constitutes a principal cause of chronic neurological disability globally, frequently precipitating profound upper limb motor impairment that compromises functional autonomy and overall quality of life.
- Trial name
- NCT07604181
- Testing
- Constraint-Induced Movement Therapy within a clinical setting, Constraint-Induced Movement Therapy Via Telerehabilitation
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- University of Faisalabad
Stroke
Effects of CHRIST on Upper Limb Function in Children With Pediatric Stroke
Pediatric stroke poses significant challenges due to its impact on a child's developing brain. Both ischemic and hemorrhagic strokes in children can result in long-term motor, sensory, and cognitive impairments, particularly…
- Trial name
- NCT07441057
- Testing
- CHRIST
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Stroke, Sensorimotor Impairment Affecting the Upper Limb
Effectiveness of Active Exploration of Simulated Textures for Sensorimotor Recovery
Parallel-group, single-blinded controlled clinical trial. The study includes people aged 18-80 years, more than one month after stroke, with confirmed diagnosis, MoCA ≥ 20, and Barthel Index ≥ 3.
- Conditions
- Stroke, Sensorimotor Impairment Affecting the Upper Limb, Sensory Deficit, Rehabilitation
- Trial name
- NCT06962397
- Testing
- Active Touch-Based Sensory Training
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
ICU Acquired Weakness
Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients
Chair positioning is one of a series of early mobilization techniques. At present, this technique, which involves moving a patient out of the resuscitation bed, can be performed passively or actively.
- Trial name
- STORM (NCT06973746)
- Testing
- sitting out of bed in an arm-chair position
- Where
- 11 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Thoracic Surgery
Effect of Digital Physiotherapy Practice on Pulmonary Function, Muscle Strength, Quality of Life After Thoracic Surgery
Thoracic surgery is the primary intervention used in the treatment of diseases affecting the lungs, pleura, chest wall, and mediastinum.
- Trial name
- NCT07133672
- Testing
- Exercise, Standard care
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Asthma
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\xa0The purpose of this study is to assess how depemokimab, a…
- Trial name
- NCT06979323
- Testing
- Depemokimab
- Where
- 50 sites in United States, Belgium and 10 more
- Volunteers
- 150 people
- Sponsor
- GlaxoSmithKline
Hemophilia, Upper Extremity
Comparison of Upper Extremity Functional Performance in Hemophilic and Healthy Children
The goal of this observational study is to evaluate the functional performance of the upper extremity joints (scapula, shoulder, elbow, and wrist) in haemophilic children and compare muscle strength and ADL limitations with…
- Conditions
- Hemophilia, Upper Extremity, Strength, Performance
- Trial name
- NCT06826209
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Heart Failure, Implantable Cardioverter Defibrillator (ICD)
Upper Extremity Function in Patients With Reduced Ejection Fraction Heart Failure and Cardiac Implantable Electronic Devices
The aim of this study is to evaluate in detail the factors that determine upper extremity function, determine its effect on prognosis, hospital admission, hospitalization, and mortality, and examine the results according to the…
- Conditions
- Heart Failure, Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronisation Therapy (CRT), Reduced Ejection Fraction Heart Failure
- Trial name
- NCT07253909
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University