Clinical trials: Upper Extremity Impairments
Disability Physical
Evaluation of ORTHOPUS Partner Arm in People With Disabilities Needing for Robotic Assistance to Compensate for Upper Limb Deficiency
The study is a prospective, multicenter, interventional, open clinical trial, in Single Case Experimental Design (SCED) in multiple introduction withdrawal, controlled, randomized.
- Trial name
- MS PARTNER (NCT06828510)
- Testing
- With device
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multiple Sclerosis, Primary Progressive, Cognitive Impairment
Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation
Given that up to 70% of people with secondary progressive MS are cognitively impaired, the search for effective treatments is considered a priority by people living with the disease.
- Trial name
- NCT03679468
- Testing
- Cognitive Rehabilitation, Aerobic Exercise
- Where
- Canada
- Volunteers
- 309 people
- Sponsor
- Sunnybrook Health Sciences Centre
Multiple Sclerosis
Blood Flow Restriction for Upper Limb Rehabilitation in People With Multiple Sclerosis. A Randomized Controlled Trial (BFRT-EM)
Although the Blood Flow Restriction Training (BFRT) system has attracted the attention of health professionals, research on this tool in people with neurological pathology, particularly multiple sclerosis (MS), is very limited.
- Trial name
- BFRT-EM (NCT06795230)
- Testing
- Muscle strengthening (BFRT), Conventional physical therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
Spinal Cord Injury, Tetraplegia/Tetraparesis
MEP Up-conditioning to Target Corticospinal Plasticity
Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist…
- Trial name
- uMEP2 (NCT06989905)
- Testing
- Up-conditioning of the wrist extensor motor evoked potential
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Stroke
Evaluation of a Haptic Glove for Assessing Tactile Perception in Post-Stroke Patients
The aim of the SCORES Haptic Glove Study is to assess the technical features, safety, and reliability of a sensor-equipped glove designed to evaluate tactile perception.
- Trial name
- SCORES-glove (NCT06643273)
- Testing
- Robotic rehabilitation, Conventional rehabilitation
- Where
- 3 sites in Italy
- Volunteers
- 126 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Stroke
Comparing Two Therapies to Improve Arm Function After Stroke
This clinical trial aims to compare the effects of coupling rehabilitation and constraint-induced movement therapy (CIMT) on improving arm function, hand skills, and daily activity performance in people who have upper limb…
- Trial name
- CR vs CIMT (NCT07093983)
- Testing
- Constraint-Induced Movement Therapy (CIMT), Coupling Rehabilitation
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Stroke, Arm Weakness as a Consequence of Stroke
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a…
- Conditions
- Stroke, Arm Weakness as a Consequence of Stroke, Upper Extremity Hemiparesis, Upper Extremity Impairments
- Trial name
- LIFUS-OPTIMIZE (NCT07220005)
- Testing
- Low intensity focused ultrasound stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Stroke
Sensory and Cognitive Outcomes of Robotic Exercises in Stroke (SCORES)
Based on the findings of meta-analyses, upper limb robotic rehabilitation has shown to enhance daily living activities, motor function, and strength in stroke patients.
- Trial name
- SCORES (NCT06109324)
- Testing
- Robotic Rehabilitation of the upper limb, Conventional Rehabilitation of the upper limb
- Where
- 3 sites in Italy
- Volunteers
- 126 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Lateral Epicondylitis
Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia
The purpose of this research is to compare two different approaches for treating patients with lateral epicondylalgia: electric dry needling, thrust manipulation and stretching versus impairment-based manual therapy, exercise and…
- Trial name
- NCT03167710
- Testing
- Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Hemiparetic Stroke
Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments
Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over the past two decades.
- Trial name
- NCT07599774
- Testing
- High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Carle Foundation Hospital