Clinical trials: Upper Extremity Motor Function
Cerebral Palsy
Development of a Remote Therapy Protocol for Upper Limb Function Enhancement in Children With Cerebral Palsy
The perpose of this study: Development and demonstration of a teletherapy protocol to improve upper limb function in children with cerebral palsy.
- Trial name
- NCT06272760
- Testing
- Home-based hand-arm bimanual intensive training (Tele-HABIT)
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Peripheral Nerve Injury, Peripheral Nerve Discontinuity
Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction
This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity.
- Conditions
- Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury
- Trial name
- Nerve-RESTORE℠ (NCT07657182)
- Testing
- Avance Nerve Graft, Sural nerve autograft
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Axogen Corporation
Stroke, Acute, Hemiplegia
Effects of High Frequency rTMS Combined Motor Learning on Upper Limb Motor Function in Subacute Stroke
This study is to present the effect of a program combining high frequency repetitive transcranial magnetic stimulation with motor learning on upper limb motor function and grip strength and activities of daily motion in patients…
- Trial name
- NCT05176613
- Testing
- HF-rTMS, ML
- Volunteers
- 30 people
- Sponsor
- Chungnam National University Sejong Hospital
Stroke, Brain Disease
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
The goal of this study is to verify whether the use of deep brain stimulation can improve motor function of the hand and arm and speech abilities for people following a stroke.
- Conditions
- Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- NCT06303869
- Testing
- Deep Brain Stimulation (DBS) of the Motor Thalamus
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jorge Gonzalez-Martinez
Stroke
Effects of Upper Limb Motor and Robotic Training Over Neuroplasticity and Function Capacity
The purpose of this study is to evaluate and compare the effects of upper limb training with Induced Constraint Therapy (ICT) or robotic therapy. No placebo therapy is used.
- Trial name
- NARLE1 (NCT02700061)
- Testing
- Robotic occupational therapy, Induced Constraint Therapy - ICT
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Sao Paulo General Hospital
Breast Cancer Survivor, Breast Cancer
Effects of Two Strength Exercise Programs on Upper Limb Functionality in Breast Cancer
The goal of this experimental study is to evaluate the effect of a therapeutic exercise program based on upper limb plyometric exercises in breast cancer patients and breast cancer survivors to determine changes in upper limb…
- Conditions
- Breast Cancer Survivor, Breast Cancer, Breast Cancer Patients, Breast Cancer - Female
- Trial name
- NCT06952270
- Testing
- plyometric exercise, Strength training exercise
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Vigo
Spinal Muscular Atrophy
Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam
This was a Phase IIIb open-label, single arm, multi-center study to evaluate the safety, tolerability and efficacy of OAV101B in participants with SMA aged 2 to <18 years after the discontinuation of treatment with nusinersen or…
- Trial name
- STRENGTH (NCT05386680)
- Testing
- OAV101
- Where
- 13 sites in United States, Australia and 7 more
- Volunteers
- 27 people
- Sponsor
- Novartis Pharmaceuticals
Stroke
Brain Stimulation and Tailored Interventions to Promote Recovery in Stroke Survivors
A substantial proportion of individuals are left with poor residual functioning of the affected arm after a stroke. This has a tremendous impact on the quality of life and the ability for stroke survivors to live independently.
- Trial name
- NCT02915185
- Testing
- strength training intervention, tDCS
- Where
- 3 sites in Canada
- Volunteers
- 90 people
- Sponsor
- Université de Sherbrooke