Clinical trials: Upper Extremity Weakness, open to volunteers
Post-Intensive Care Syndrome, ICU Acquired Weakness
Hand and Arm Rehabilitation Using VR
Patients admitted to the ICU due to critical illness often experience physical, mental, cognitive, or social issues. Research indicates that inadequate physical recovery is associated with lower handgrip strength, and hand…
- Trial name
- HANDQUEST (NCT06373341)
- Testing
- VR training for arm and hand rehabilitation
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- Frisius Medisch Centrum
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Stroke, Stroke Patients
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke.
- Conditions
- Stroke, Stroke Patients, Arm Weakness as a Consequence of Stroke, Brain Stimulation
- Trial name
- REALISE (NCT06765642)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Stroke, Chronic Stroke
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Texas Biomedical Device Center (TxBDC) has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT).
- Conditions
- Stroke, Chronic Stroke, Upper Extremity Paresis, Ischemic Stroke
- Trial name
- NCT04534556
- Testing
- Active Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Baylor Research Institute
Stroke, Upper Extremity Paresis
Sensory Mechanisms of Manual Dexterity Recovery After Stroke: a Prospective Cohort Study of Prediction and Cerebral Correlates
In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation.
- Conditions
- Stroke, Upper Extremity Paresis, Manual Dexterity, Sensory Integration Dysfunction
- Trial name
- HapticS 2 (NCT07340736)
- Testing
- Haptic stimulation device, Brain MRI
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke, Upper Extremity Paresis
Deep Brain Stimulation of the Dentate Nucleus for Motor Rehabilitation After Stroke
The goal of this clinical trial is to learn if deep brain stimulation of the dentate nucleus (DN-DBS) works to promote chronic post-stroke upper limb motor function in adults. It will also learn about the safety of DN-DBS.
- Trial name
- NCT06498934
- Testing
- deep brain stimulation, Rehabilitation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Beijing Municipal Administration of Hospitals
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
Constraint-Induced Therapy (CI Therapy) is a behavioral approach to neurorehabilitation and consists of multi-components that have been applied in a systematic method to improve the use of the limb or function addressed in the…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05492513
- Testing
- Grade 1 CI Therapy +Sensory Components
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Stroke
Passive Robots for Stroke Rehabilitation: A Feasibility Study
The purpose of this study is to examine the feasibility and effectiveness of a novel, multimodal approach that combines passive devices with noninvasive neuromuscular stimulation for upper extremity rehabilitation after stroke.
- Trial name
- NCT07218276
- Testing
- Functional Training with SepaRRo and NeuRRoFES
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Stroke, Upper Extremity Paresis
BCI-FES for Upper Limb Rehabilitation in Chronic Stroke
The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulation therapy coupled to P-300…
- Conditions
- Stroke, Upper Extremity Paresis, Neuronal Plasticity
- Trial name
- BCI-FES (NCT06409754)
- Testing
- Functional Electrical Stimulation Therapy coupled to a P-300 based Brain-Computer Interface, Conventional Physical Therapy
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Critical Illness
Effectiveness of Virtual Reality in Improving Upper Limb Function in Critically Ill Patients
Millions of people are hospitalized every year in Intensive Care Units (ICUs) with severe health conditions due to various causes and categories of diseases, such as stroke, Traumatic Brain Injuries (TBI), polytrauma, sepsis, and…
- Trial name
- EVOLUTION (NCT07901855)
- Testing
- Conventional Physiotherapy and Occupational Therapy, Fully Immersive Virtual Reality Training
- Where
- Greece
- Volunteers
- 48 people
- Sponsor
- National and Kapodistrian University of Athens
Moderate Arm Paresis, Ischemic Stroke
Comparison of Four-Channel Functional Electrical Stimulation vs. One-Channel Electrical Stimulation on Moderate Arm/Hand Paresis in Subacute Stroke Patients
This study will compare two treatments that may help participants recover after having suffered from stroke. Persons who experience weakness or paralysis of their arms/hands will be randomly placed in one of two groups.
- Trial name
- MKES2 (NCT07098572)
- Testing
- Cyclic single channel neuromuscular stimulation, Electromyogram-triggered 4 channel neuromuscular stimulation
- Where
- 3 sites in Austria
- Volunteers
- 44 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Stroke
Telerehabilitation for Post-Stroke Hand Function
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke.
- Trial name
- NCT07792655
- Testing
- Technology-Supported Hand Training, Pamphlet-Supported Hand Activity
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Stroke
At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.
The goal of this clinical trial is to learn if wearable sensor data visualization on smartphones can improve the use of the stroke-affected limb during everyday activities.
- Trial name
- NCT06787729
- Testing
- mHealth
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spaulding Rehabilitation Hospital