Clinical trials: Upper Extremity Wound
Distal Radius Fracture
Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures
The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures.
- Trial name
- NCT03898154
- Testing
- Dexamethasone, Methylprednisolone
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- C. Liam Dwyer
Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury
Investigating the Effectiveness of Graded Motor Imagery Training in Children With Obstetric Brachial Plexus Injury
The aim of this study is to investigate the effect of graded motor imagery training on upper extremity motor function, proprioception, functional mobility, balance and quality of life in patients with obstetric brachial plexus…
- Conditions
- Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury, Neonatal Brachial Plexus Palsy
- Trial name
- NCT06966544
- Testing
- Conventional Physiotherapy, Graded Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Bakircay University
Child
Treatment of Displaced Radial Neck Combined With Olecranon Fractures
This study aimed to evaluate the outcomes of using absorbable rods and Kirschner Wires technique for severe displaced radial neck fractures combined with olecranon fractures in children.
- Trial name
- NCT04424498
- Testing
- Absorbable Rods and Kirschner Wires
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Pain, Postoperative, Pain, Acute
Dexamethasone Versus Dexmedetomidine as Adjuvants for Nerve Blocks
When used as perineural (PN) adjuvants to local anesthetics (LAs), dexamethasone (DX) and dexmedetomidine (DXD) have been well documented to prolong the duration of peripheral nerve blocks.
- Conditions
- Pain, Postoperative, Pain, Acute, Upper Extremity Injury
- Trial name
- NCT03610893
- Testing
- Dexamethasone, Dexmedetomidine
- Where
- Chile
- Volunteers
- 120 people
- Sponsor
- University of Chile
Distal Radius Fracture
Mini-C-Arm for Distal Radius Fractures in Adults
Determine efficacy of the use of mini-c-arm fluoroscopy for the closed reduction of isolated distal radius fractures in adult patients in the emergency department setting.
- Trial name
- NCT03396965
- Testing
- Mini-c-arm
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Spinal Cord Injury
Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury
The objective of this research program is to conduct a multi-site clinical randomized control trial that will evaluate the efficacy of functional electrical stimulation based upper limb intervention for people with tetraplegia.
- Trial name
- MCRCT (NCT01292811)
- Testing
- Functional Electrical Stimulation (Compex Motion Stimulator), Conventional Occupational therapy
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Toronto Rehabilitation Institute
Forearm Fracture, Radius Fractures
Pain Palliation in Forearm Fractures in the Emergency Department
The aim is to evaluate the success of reduction procedures and pain palliation in patients with forearm fractures undergoing reduction under procedural sedation-analgesia (PSA) and ultrasound (US)-guided infraclavicular nerve…
- Conditions
- Forearm Fracture, Radius Fractures, Ulnar Fracture
- Trial name
- NCT06588907
- Testing
- Bupivacaine Hydrochloride, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ankara Etlik City Hospital
Multiple Myeloma, Newly Diagnosed
ASCT Combined With BCMA CAR-T and GPRC5D/CD3 BiTEs Maintenance for Transplant-Eligible Ultra-High-Risk Multiple Myeloma
This is a prospective, single-arm, phase II study to evaluate the efficacy and safety of autologous stem cell transplantation combined with BCMA CAR-T therapy followed by GPRC5D/CD3 bispecific antibody maintenance in…
- Trial name
- CAREMM-005 (NCT07106710)
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, BCMA CAR-T, GPRC5D/CD3 BiTEs
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Alzheimer's Disease, Amyotrophic Lateral Sclerosis
Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases.
This is a prospective investigation of the effects of Laughter therapy (LT) on perceived stress, self-efficacy, mood and other wellness measures in people with the following neurological conditions: Alzheimer's disease…
- Conditions
- Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Brain Injury, Huntington's Disease
- Trial name
- NCT02750982
- Testing
- Laughter Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brown, Theodore R., M.D., MPH
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Epicondylitis, Lateral
Feasibility and Efficacy of Bone Marrow PRP Injection in Refractory Fissure Tendinopathies of the Lateral Epicondylar Tendons
Lateral epicondylitis with tendon tear resistant to conservative treatment remains a common clinical condition with limited therapeutic options before surgery is considered.
- Trial name
- EPI-PRP (NCT07717203)
- Testing
- Bone Marrow-Derived PRP, Peripheral Blood-Derived PRP
- Volunteers
- 24 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Magnetotherapy, Carpal Tunnel Syndrome (CTS)
Magnetotherapy in Carpal Tunnel Syndrome: Randomized Controlled Study
This study is designed to investigate the effectiveness of low-frequency pulsed electromagnetic field therapy in individuals diagnosed with mild-to-moderate carpal tunnel syndrome (CTS).
- Conditions
- Magnetotherapy, Carpal Tunnel Syndrome (CTS), Median Nerve Compression
- Trial name
- NCT07435961
- Testing
- Arm 1: Active Magnetotherapy Group, Arm 3: Conservative Treatment (Wait-List Control) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abdominal Surgery, Colon Surgery
D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Subjects who are planned to undergo an abdominal (colon) surgery and who will meet the study entry criteria will be randomly divided into 2 groups: for half D-PLEX will be administered concomitantly with the standard of care…
- Conditions
- Abdominal Surgery, Colon Surgery, Post-Op Infection
- Trial name
- NCT03633123
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 8 sites in Israel
- Volunteers
- 202 people
- Sponsor
- PolyPid Ltd.
Wrist Injuries, Postoperative Pain Control
Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery
The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to local infiltration done in adult patients having wrist arthroscopy surgery.
- Trial name
- NCT02970097
- Testing
- 20ml bolus of 0.5% ropivicaine, 10 ml of 0.5% ropivicaine, Midazolam
- Where
- United States
- Sponsor
- University of Pennsylvania
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Distal Radius Fracture
Novel Exercises to Facilitate Recovery of Supination and Pronation for Distal Radius Fractures Managed With a Volar Plate
The primary objective of this study is to evaluate the influence of elbow position on achieving forearm supination and pronation and wrist ROM postoperatively.
- Trial name
- NCT05850325
- Testing
- Group 1 Elbow Flexed at 90 Degrees, Group 2 Elbow Fully Flexed
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Indiana Hand to Shoulder Center
Spinal Fusion, Spinal Deformity
Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation
Background: Throughout the history of spinal deformity there have been continuous advances in the surgical treatment. Although many techniques have been successfully developed despite the anatomy complex, screw placement still…
- Conditions
- Spinal Fusion, Spinal Deformity, Spine Injury
- Trial name
- NoHARM (NCT06020417)
- Testing
- O-ARM (Medtronic, Inc, Louisville, CO), Conventional corrective surgery for arthrodesis
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Federal University of Piaui
Scapula Fracture, Glenoid; Fracture
Clinical Outcomes Following Glenoid Neck Fracture as Correlated With Quantitative Assessment of Osseous Injury
A significant subset of patients with scapula fractures also involves the glenoid neck (bone joining the shoulder joint the scapular body).
- Trial name
- NCT00644813
- Testing
- Scapular with glenoid neck fractures
- Where
- 13 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- Boston Medical Center
Rotator Cuff Tears, Rheumatoid Arthritis Shoulder
Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study
The goal of the Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study is to collect safety and performance data on the commercially available Shoulder iD™ Primary Reversed Glenoid device.
- Conditions
- Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus
- Trial name
- SiD (NCT05868148)
- Testing
- Shoulder iD™ Primary Reversed Glenoid
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
Spinal Cord Injuries
Effects of Activity Based Therapy on Upper Limb Strength and Transfer in Spinal Cord Injury Patients
In our society spinal cord injury is a major problem.activity based therapy and conventional therapy has a potentional to improve upper limb strength and transfer in tetraplegic patients.
- Trial name
- NCT04823078
- Testing
- Activity base therapy, Strength training
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University