Clinical trials: Upper Gastrointestinal Bleeding
Upper Gastrointestinal Bleeding
Use of PillCam ESO2 in Triaging Patients Present With Upper GIB
Background Patients presented to hospital with coffee ground vomiting and black stool may not be actually having upper gastrointestinal bleeding (UGIB) Hospital admission can be avoided if serious UGIB can be excluded To date…
- Trial name
- NCT02446678
- Testing
- PillCam ESO2
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding
ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASA
Peptic ulcer bleeding associated with ASA or NSAIDs is a major cause of hospitalization in Hong Kong. The investigators previously showed that ASA or NSAIDs accounted for about half of all cases of hospitalizations for peptic…
- Trial name
- NCT01408186
- Testing
- Rabeprazole, Famotidine
- Where
- 8 sites in Hong Kong, Japan
- Volunteers
- 264 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding
Evaluation of Prognostic Scores in Patients With Upper Gastrointestinal Bleeding and Cancer
This is a prospective and observational study to evaluate oncologic patients that presented upper gastrointestinal bleeding with the use of some prognostic scores.
- Trial name
- NCT02508883
- Where
- Brazil
- Volunteers
- 243 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Upper Gastrointestinal Bleeding
Randomized Trial of Outpatient vs. Inpatient Management of Low-risk Patients With Upper Gastrointestinal Bleeding.
Patients presenting to the emergency room with upper gastrointestinal bleeding and a Glasgow Blatchford score of zero will be randomly assigned to further care in the inpatient vs. outpatient setting.
- Trial name
- NCT02005705
- Testing
- Outpatient Management of Low-risk Patients, Inpatient Management of Low-risk Patients
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Upper Gastrointestinal Bleeding
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
The non-variceal upper gastrointestinal bleeding is defined as gastrointestinal bleeding located proximal to the angle of Treitz, whose cause is not related to esophagogastric varices or gastropathy of portal hypertension.
- Trial name
- NCT02537353
- Testing
- Metal clips, Hemospray, Endoscopy Exam
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Non-variceal Upper Gastrointestinal Bleeding
Surgicel® (Fibrillar) in Non-variceal UGI Bleeding
The aim of this study is to assess of effect of Surgicel® (Fibrillar) for preventing delayed bleeding after endoscopic hemostasis in non-variceal upper gastrointestinal bleeding
- Trial name
- NCT02054260
- Testing
- Surgicel
- Where
- South Korea
- Sponsor
- Soonchunhyang University Hospital
Upper Gastrointestinal Bleeding, Hexacapron
The Use of Hexacapron in Upper Gastrointestinal Bleeding
The purpose of this study is to conduct a randomized control trial, double-blind study to compare Hexacapron with standard of care treatment to standard of care alone to evaluate the efficacy of adding effect of Hexacapron to…
- Conditions
- Upper Gastrointestinal Bleeding, Hexacapron, Hemostasis, Rebleeding
- Trial name
- HEXUGI (NCT02071316)
- Testing
- Hexacapron( Tranexamic acid), esomeprazole
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Shaare Zedek Medical Center
Schistosomiasis Mansoni, Portal Hypertension
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery
Upper gastrointestinal bleeding (UGIB) is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni.
- Conditions
- Schistosomiasis Mansoni, Portal Hypertension, Upper Gastrointestinal Bleeding
- Trial name
- NCT01931826
- Testing
- Endoscopic treatment, Total EGDS+ endoscopy
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
Upper Gastrointestinal Bleeding
Study of Incidence of Drug-induced Upper Gastrointestinal Bleeding
The purpose of this study is to determine and analyse the incidence, severity, risk factors and routine management of acute drug-induced upper gastrointestinal bleeding (UGIB) in the population of Russian patients
- Trial name
- NCT01155401
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Upper Gastrointestinal Bleeding
A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01275937
- Testing
- Esomeprazole
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Taipei Medical University
Upper Gastrointestinal Bleeding, Cirrhosis
Transfusion Requirements in Gastrointestinal (GI) Bleeding
Recently it has been suggested that a restrictive transfusion of units of Red Cells (URC) may improve the outcome of ICU patients with anemia.
- Conditions
- Upper Gastrointestinal Bleeding, Cirrhosis, Portal Hypertension
- Trial name
- NCT00414713
- Testing
- red blood cell transfusion
- Where
- Spain
- Volunteers
- 860 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Non-variceal Upper Gastrointestinal Bleeding, Gastrointestinal Ulcer
European Survey of Non-Variceal Upper Gastro Intestinal Bleeding (NVUGIB)
The aim of this study is to assess the current management strategies in a pan-European "real-life" setting to uncover the unmet need in this area: non-variceal gastrointestinal bleedings.
- Conditions
- Non-variceal Upper Gastrointestinal Bleeding, Gastrointestinal Ulcer, Gastrointestinal Hemorrhage
- Trial name
- ENERGIB (NCT00797641)
- Where
- 97 sites in Belgium, Greece and 5 more
- Volunteers
- 2,500 people
- Sponsor
- AstraZeneca
Nonvariceal Upper Gastrointestinal Bleeding
Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding
Introduction: Proton pump inhibitor (PPI) is the drug of choice used in patients with non-variceal upper gastrointestinal tract bleeding (UGIB).
- Trial name
- NCT00861640
- Testing
- Intravenous Omeprazole, Oral Rabeprazole
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Upper Gastrointestinal Bleeding
HDUPE 2004: Gastro-Oesophageal Haemorrhage in Emergency : Gastric Préparation to Endoscopy
Gastric lavage is usually used for gastric preparation before endoscopy in patients with upper gastrointestinal bleeding. However, the benefit-risk balance of putting a nasogastric tube in these patients is not clearly defined.
- Trial name
- NCT00259220
- Testing
- erythomycin, gastric lavage alone, erythromycine and gastric lavage
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Peptic Ulcers, Upper Gastrointestinal Bleeding
High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding
High intravenous dosage of Proton Pump Inhibitors is not better than standard dosage in bleeding peptic ulcers successfully treated by endoscopic therapy
- Trial name
- NCT00374101
- Testing
- omeprazole, pantoprazole
- Where
- 10 sites in Italy
- Volunteers
- 450 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS