Clinical trials: Upper Limb Nerve Block
Postoperative Pain
Phase 2B Upper Extremity Nerve Block Study
This is a Phase 2B, randomized, assessor-blind, active- and saline placebo-controlled, multicenter study in subjects undergoing augmentation mammoplasty to evaluate the analgesic efficacy, safety, and pharmacokinetics (PK) of…
- Trial name
- NCT03011333
- Testing
- HTX-011, Bupivacaine HCl without epinephrine
- Where
- 2 sites in United States
- Volunteers
- 243 people
- Sponsor
- Heron Therapeutics
Upper Limb Injury, Intracranial Pressure Increase
Evaluation of Supraclavicular Brachial Plexus Blocks at Various Volumes: Impact on Optic Nerve Sheath Diameter
This study aimed to evaluate the anesthesia adequacy, side effects, and complication rates, as well as the postoperative pain relief effectiveness of supraclavicular brachial plexus blocks administered at different volumes under…
- Trial name
- NCT06428461
- Testing
- Supraclavicular brachial plexus block, Measurement of Optic Nerve Sheath Diameter (ONSD) Using B-Mode Ultrasound, Assessment of Peripheral Nerve Block Success Using Perfusion Index Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Pamukkale University
Anaesthesia
Ultrasound Guided Intercostobrachial Nerve Block
The intercostobrachial nerve underlies many anatomical variations. For surgery of the upper arm the axilla is usually not anaesthetized by a brachial plexus block, which therefore needs to be completed by an intercostobrachial…
- Trial name
- NCT02805582
- Testing
- 10ml ropivacain 0.5%
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Dr. Christoph Ilies
Anesthesia, Local
Oral Dexamethasone as an Adjunct to a Brachial Plexus Block in Patients Undergoing Orthopaedic Surgery of the Forearm and Hand
The investigators will assess the beneficial and harmful effects of oral dexamethasone (12 mg or 24 mg) versus placebo in patients undergoing orthopaedic surgery of their hand or forearm with a lateral infraclavicular brachial…
- Trial name
- ADJUNCT1 (NCT04853446)
- Testing
- Dexamethasone 12 mg, Dexamethasone 24 mg
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- Zealand University Hospital
Nerve Block
Continuous Infraclavicular Nerve Blocks: Needle Versus Catheter Local Anesthetic Bolus
The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset…
- Trial name
- NCT01377545
- Testing
- Local Anesthetic given via perineural catheter for infraclavicular nerve block., Local Anesthetic given via needle for infraclavicular nerve block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pain
Trial Comparing the Onset and Duration of Ultrasound Guided Supraclavicular Nerve Blocks Using Ropivacaine Versus Ropivacaine-Chloroprocaine Mixture
A double blinded randomized controlled trial comparing the onset and duration of the Onset and Duration of Ultrasound Guided Supraclavicular Nerve Blocks Using a long acting local anesthestic (Ropivacaine) with a mixture of a…
- Trial name
- NCT01719237
- Testing
- Ropivacine and Chloroprocaine mixture, Ropivacaine only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Fractures, Closed, Humeral Fractures
Regional Blocks for Lateral Condyle Fractures
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning.
- Conditions
- Fractures, Closed, Humeral Fractures, Pain
- Trial name
- NCT03796572
- Testing
- Ropivacaine, Puncture Wound and Dressing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Lower Extremity Surgery, Upper Extremity Surgery
Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks
This is a research study to determine if the effects of continuous peripheral nerve blocks are influenced by the distance of insertion past the needle tip of the perineural catheter.
- Conditions
- Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
- Trial name
- NCT00997867
- Testing
- Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of California, San Diego
Radius Fractures
Comparison 1 Plane-1 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block
Ultrasound-guided supraclavicular brachial plexus block (US-SCBPB) has been a generalized regional anesthesia in upper extremity surgery.
- Trial name
- US-SCBPB (NCT02505633)
- Testing
- Stimuplex insulated needle, lidocaine mixed with epinephrine
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Shoulder Pain
Intravenous Versus Perineural Effect Dexamethasone in Interscalene Nerve Block With Levobupivacaine
Interscalene brachial plexus block can be used as an additive to general anaesthesia or as the primary anaesthetic for shoulder surgeries for pain management.
- Trial name
- NCT04284007
- Testing
- Perineural levobupivacaine, Perineural dexamethasone in addition to levobupivacaine, Intravenous dexamethasone with perineural levobupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Pelvic Organ Prolapse, Surgery
Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery
To test the hypothesis that preoperative injections along the levator ani muscles and pudendal nerve with bupivacaine and dexamethasone improve pain control after vaginal apical reconstructive surgery.
- Conditions
- Pelvic Organ Prolapse, Surgery, Postoperative Pain
- Trial name
- NCT03040011
- Testing
- Dexamethasone, Bupivacaine, Bilateral Pudendal Nerve Block
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Lauren Giugale, MD
Radius Fracture Distal, Rebound Pain
Ropivacaine Concentration and Rebound Pain
The goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults.
- Trial name
- NCT06950372
- Testing
- Ropivacaine concentration low, Ropivacaine concentration high
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Regional Anesthesia, Regional Anesthesia Block
Neurological Events and Unforeseen Risks After Locoregional-anesthesia
This is a multicenter, prospective, observational study aimed at determining the incidence of neurological and non-neurological complications following locoregional anesthesia procedures.
- Trial name
- NEURAL (NCT07238933)
- Testing
- Observational assessment after regional anesthesia
- Where
- 4 sites in Italy
- Volunteers
- 3,396 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Nerve Block, Upper Extremity Surgery
Ropiclobet for Regional Anesthesia and Post-Operative Pain Control in Upper Extremity Surgery
This is a national, single-center, single-arm, open-label Phase II clinical trial designed to evaluate the efficacy and safety of Ropiclobet, a fixed-dose injectable solution containing Ropivacaine HCl, Betamethasone Sodium…
- Trial name
- NCT07131657
- Testing
- Ropivacaine + Clonidine + Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- PHARMAFINA