Clinical trials: Upper Limb Paresis
Upper Extremity Weakness, Stroke
A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis
The primary purpose of this study is to establish that application of a Sequential Compression Device (SCD) and lower extremity (LE) sleeve applied to a hemi-paretic upper extremity is safe.
- Trial name
- NCT05535257
- Testing
- Sequential Compression Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Stroke, Weakness, Muscle
EMG Training for Altering Activation Patterns After Stroke
Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.
- Conditions
- Stroke, Weakness, Muscle, Coordination Lack
- Trial name
- NCT03619772
- Testing
- Bilateral, Unilateral
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Hand Function, Stroke
TheraBracelet Phase I
This project aims to test a new technology that may improve hand function impaired from a stroke, thereby improving independence and quality of life.
- Conditions
- Hand Function, Stroke, Upper Extremity, Hemiparesis
- Trial name
- NCT03318341
- Testing
- Real Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- TheraBracelet, Inc.
Spasticity, Muscle, Spinal Cord Injuries
Long-term Efficacy of Spasticity-correcting Surgery and Botulinum Toxin Injections for Upper Limb Spasticity Treatment
Spasticity - a variety of motor over-activity and part of the upper motor neuron syndrome - is a common cause of impaired motor function after brain injuries of different etiologies.
- Conditions
- Spasticity, Muscle, Spinal Cord Injuries, Traumatic Brain Injury, Stroke
- Trial name
- NCT03910101
- Testing
- Hand surgery and intensive rehabilitation
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Vastra Gotaland Region
Hemiparesis, Cerebral Palsy
Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study)
What is the CHAMP Study? The CHAMP Study is a multisite clinical trial funded by the National Institutes of Health that is comparing the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy…
- Conditions
- Hemiparesis, Cerebral Palsy, Brain Injury
- Trial name
- CHAMP (NCT01895660)
- Testing
- Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Virginia Polytechnic Institute and State University
Stroke, Upper Extremity Dysfunction
Implementing Outcome Measures in Stroke Rehabilitation
The primary objective of this study is to tailor and test implementation strategies to support the adoption of two upper extremity motor outcome measures for stroke: the Fugl-Meyer Assessment and the Action Research Arm Test.
- Conditions
- Stroke, Upper Extremity Dysfunction, Hemiplegia, Hemiparesis
- Trial name
- I-STROM (NCT04888416)
- Testing
- I-STROM
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Stroke, Hemiparesis
Efficacy of a Combined Transcranial Direct Current Stimulation and Virtual Reality Intervention
Rehabilitation options for stroke survivors who present severe hemiparesis in chronic stages are limited and may end in compensation techniques that involve the use of the less affected arm to achieve some degree of functional…
- Conditions
- Stroke, Hemiparesis, Chronic Stroke, Upper Limb Injury
- Trial name
- REACT01 (NCT03528018)
- Testing
- REACt system, Physical therapy
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Hospitales Nisa
Cerebral Palsy, Hemiplegia
Adaptive Arm Training for Children With Hemiplegia
The goal of this research is to provide limb training in children with hemiplegia using a bimanual-to-unimanual training approach.
- Conditions
- Cerebral Palsy, Hemiplegia, Hemiparesis, Acquired Brain Injury
- Trial name
- NCT03387449
- Testing
- Bimanual Arm Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Blythedale Children's Hospital
Pediatric Hemiparesis
INFLUENCE OF VOJTA THERAPY IN CEREBRAL PALSY. INFANTILE HEMIPARESIS
This study describes a single pediatric case with hemiparesis who received a specialized physiotherapy intervention based on the Vojta method.
- Trial name
- NCT07331948
- Testing
- Vojta therapy session
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Centro Integral Kaplan
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Upper Limb Weakness Due to Central Neurologic Injury, Upper Limb Weakness Due to Peripheral Neurologic Injury
mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation
The purpose of this Phase I study is to conduct a pilot clinical trial using a mobile app-connected, wire-free surface electromyography (sEMG) system, called mGain, that provides biofeedback-based therapy in individuals with…
- Conditions
- Upper Limb Weakness Due to Central Neurologic Injury, Upper Limb Weakness Due to Peripheral Neurologic Injury, Upper Limb Weakness Due to Nerve Reconstruction, Upper Limb Weakness Due to Tendon Transfer Surgery
- Trial name
- NCT06023316
- Testing
- mGain system
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Orthocare Innovations, LLC
Stroke, Cerebrovascular Disorders
Dose Optimization for Stroke Evaluation
This study is about rehabilitation of arm function after a stroke. The investigators are testing the dosage of therapy that is needed for meaningful recovery of arm and hand function.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Ischemia, Infarction
- Trial name
- DOSE (NCT01749358)
- Testing
- Accelerated Skill Acquisition Program (ASAP), Active Monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Stroke, Upper Limb Paresis
Effects of High-Frequency rTMS on Cortical Motor Mapping in Stroke Patients With Severe Upper Limb Impairment (MAP2024SJD)
The goal of this clinical trial is to learn if a single session of high-frequency repetitive transcranial magnetic stimulation (rTMS) can increase cortical motor activity in stroke patients with severe upper limb impairment.
- Trial name
- MAP2024SJD (NCT07787793)
- Testing
- High-frequency repetitive transcranial magnetic stimulation
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Ancor Rebassa Cabrera
Spinal Cord Injury, Spinal Cord Injury at C5-C7 Level
Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury
The goal of this prospective, open-label cohort study is to assess functional outcomes in individuals with cervical spinal cord injury who have undergone nerve transfer surgery to restore upper limb function.
- Conditions
- Spinal Cord Injury, Spinal Cord Injury at C5-C7 Level, SCI - Spinal Cord Injury, Upper Extremity Paralysis
- Trial name
- NCT05638191
- Testing
- Nerve transfer surgery
- Where
- 4 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Stroke, Stroke Patients
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke.
- Conditions
- Stroke, Stroke Patients, Arm Weakness as a Consequence of Stroke, Brain Stimulation
- Trial name
- REALISE (NCT06765642)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke), Age Between 18-75 Years
Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
The purpose of this study is to evaluate changes in strategies of hemiparetic upper limb movement in chronic stroke patients following rehabilitation using the "Nintendo Wii".
- Trial name
- WII (NCT01806883)
- Testing
- WII Rehabilitation, Traditional rehabilitation
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
CVA (Cerebrovascular Accident), Paresis
Robotic Enhanced Error Training of Upper Limb Function in Post-stroke Patients
Background: Stroke is a common cause of morbidity, including paresis, and stroke survivors often have reduced function in their paretic arm.
- Trial name
- NCT05174676
- Testing
- Dextreme
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Reuth Rehabilitation Hospital
Cerebrovascular Stroke
Fast Arm Motor Skill Training in Chronic Stroke Survivors
Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation.
- Trial name
- FAST (NCT05013762)
- Testing
- Fast intervention, Active Monitoring
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Southern California
Stroke, Upper Extremity Paresis
Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke
This study will evaluate the safety and effectiveness of Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) for improving motor recovery after stroke.
- Trial name
- NCT03292159
- Testing
- Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital